Resumen de Investigación
Analyzed using Evidence Intelligence™

Artificial pancreas may improve glucose control in type 1 diabetes

Última actualización 18 de agosto de 2026

Key finding

HCL had a lower mean blood glucose of 6.93 ± 0.99 mmol/L compared to MDI's 8.03 ± 2.17 mmol/L.

Android‐HCL therapy compared to insulin multi‐injection therapy in patients with type 1 diabetes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

Android‐HCL therapy compared to insulin multi‐injection therapy in patients with type 1 diabetes.

Clinical relevance

This study evaluated Android‐HCL therapy compared to insulin multi‐injection therapy in patients with type 1 diabetes.

Keep in mind

Limitations were not clearly described in the extracted text.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Shaohua L, Pin L, Haosi L, et al. Efficacy and Safety of Artificial Pancreas in Patients with Type 1 Diabetes Mellitus. Case Reports in Endocrinology. 2026;2026. doi:10.1155/crie/8925266

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Hybrid closed-loop system, Insulin therapy and Blood glucose, Hypoglycemia events, Time above range, and 2 more.

Primary intervention

Hybrid closed-loop system

Primary outcomes

  • Blood glucose
  • Hypoglycemia events
  • Time above range

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

10
Evidence pairs
10
Relationships
4
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

4

Related topics

10

Evidence pairs

599

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 10 evidence relationships
  • Includes primary outcome data
  • Linked to 4 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Relación de evidencia

Insulin Delivery Systems and CGM Time in Range

Evidencia relacionada

Relación de evidencia

Insulin Delivery Systems and Hypoglycemia

Guardar evidencia

Relación de evidencia

Insulin Therapies and Fasting Glucose

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Blood glucose

Hybrid closed-loop system → Blood glucose

Hybrid closed-loop system → Blood glucose

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 3 studies
ImpactScore™
83
Positive
ConsistencyScore™
100
consistent
Estudios de apoyo: Basado en 3 estudios
Add to Evidence Tracker

Hypoglycemia events

Hybrid closed-loop system → Hypoglycemia events

Hybrid closed-loop system → Hypoglycemia events

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 4 studies
ImpactScore™
50
Neutral
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 4 estudios
Add to Evidence Tracker

Time above range

Hybrid closed-loop system → Time above range

Hybrid closed-loop system → Time above range

Evidence Intelligence™
EvidenceScore™
78
Strong
ImpactScore™
83
Positive
ConsistencyScore™
100
consistent
Estudios de apoyo: Basado en 3 estudios
Add to Evidence Tracker

Time below range

Hybrid closed-loop system → Time below range

Hybrid closed-loop system → Time below range

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 2 estudios
Add to Evidence Tracker

Time in range

Hybrid closed-loop system → Time in range

Hybrid closed-loop system → Time in range

Evidence Intelligence™
EvidenceScore™
86
Strong
ImpactScore™
79
Positive
ConsistencyScore™
70
generally_consistent
Estudios de apoyo: Basado en 12 estudios
Add to Evidence Tracker

Blood glucose

Insulin therapy → Blood glucose

Insulin therapy → Blood glucose

Evidence Intelligence™
EvidenceScore™
77
Strong
ImpactScore™
67
Slightly Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 3 estudios
Add to Evidence Tracker

Hypoglycemia events

Insulin therapy → Hypoglycemia events

Insulin therapy → Hypoglycemia events

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 3 studies
ImpactScore™
67
Slightly Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 3 estudios
Add to Evidence Tracker

Time above range

Insulin therapy → Time above range

Insulin therapy → Time above range

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 2 estudios
Add to Evidence Tracker

Time below range

Insulin therapy → Time below range

Insulin therapy → Time below range

Evidence Intelligence™
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Time in range

Insulin therapy → Time in range

Insulin therapy → Time in range

Evidence Intelligence™
EvidenceScore™
82
Strong
ImpactScore™
70
Positive
ConsistencyScore™
60
generally_consistent
Estudios de apoyo: Basado en 5 estudios
Add to Evidence Tracker

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Insulin Delivery Systems and CGM Time in Range, Insulin Therapies and CGM Time in Range.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Insulin Delivery Systems improve cgm time in range?

Strong Evidence

Insulin Delivery Systems may improve CGM Time in Range.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    Time in range

    EvidenceScore™ Strong | EvidenceScore™ 86.0 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study

  2. 2

    Time above range

    EvidenceScore™ Strong | EvidenceScore™ 78.3 | moderate positive | ConsistencyScore™ Consistent | 1 study

  3. 3

    Time below range

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is based on 20 supporting studies with generally consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
20 supporting studiesUpdated: Aug 2026

Does Insulin Delivery Systems affect hypoglycemia?

Strong Evidence

Insulin Delivery Systems may improve Hypoglycemia.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Hypoglycemia events

    EvidenceScore™ Strong | EvidenceScore™ 79.0 | neutral | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Population details are unavailable.
8 supporting studiesUpdated: Aug 2026

Does Insulin Therapies improve fasting glucose?

Strong Evidence

Insulin Therapies may improve Fasting Glucose.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Blood glucose

    EvidenceScore™ Strong | EvidenceScore™ 77.4 | weak positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is based on 8 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
8 supporting studiesUpdated: Aug 2026

Does Insulin Therapies improve cgm time in range?

Strong Evidence

Insulin Therapies appears to improve CGM Time in Range.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Time below range

    EvidenceScore™ Strong | EvidenceScore™ 85.1 | neutral | ConsistencyScore™ Unclear | 1 study

  2. 2

    Time in range

    EvidenceScore™ Strong | EvidenceScore™ 81.8 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study

  3. 3

    Time above range

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is based on 10 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
10 supporting studiesUpdated: Aug 2026
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