Última actualización 4 de julio de 2026
Key finding
FBS decreased from 150.18 ± 34.78 mg/dL at baseline to 134.24 ± 39.91 mg/dL by the end of the study.
This study evaluated the effectiveness, safety, and tolerability of F-Biotic™ in patients with Type 2 Diabetes Mellitus, finding significant improvements in fasting and postprandial blood sugar levels.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
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Study focus
This study evaluated the effectiveness, safety, and tolerability of F-Biotic™ in patients with Type 2 Diabetes Mellitus, finding significant improvements in fasting and postprandial blood sugar levels.
These findings suggest that F-Biotic™ could be a beneficial addition to the management of Type 2 Diabetes Mellitus, particularly in controlling blood sugar levels and enhancing patients' quality of life. Such improvements could lead to better overall diabetes management and potentially reduce the risk of diabetes-related complications.
No significant changes in HbA1c, fasting insulin, or insulin resistance were observed. The study may have limited generalizability due to specific population characteristics. Effectiveness of F-Biotic™ remains unclear for some outcomes.
Published in
Publication details and source links for this paper.
Alexander M, John RA, Smiju D, Sheejamol S, Santhosh KAK, Balprakash N. Effectiveness, Safety, and Tolerability of F-Biotic™ in Patients with Type 2 Diabetes Mellitus. Cureus. 2024;16(12):e76053. doi:10.7759/cureus.76053
Fasting Blood Sugar decreased by 15.94 mg/dL (p=0.037).
Postprandial Blood Sugar decreased by 32.97 mg/dL (p=0).
Quality of Life improved significantly in the F-Biotic group.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to F-Biotic Arishina and Fasting blood sugar (FBS), Fasting insulin levels, GLP-1, and 5 more.
This study contributes evidence to
Primary intervention
F-Biotic Arishina
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
8
Evidence pairs
319
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
matched_outcome
Evidencia relacionada
Tema de evidencia
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Core evidence
The primary outcomes reported in this study.
F-Biotic Arishina → Fasting blood sugar (FBS)
F-Biotic Arishina → Fasting blood sugar (FBS)
F-Biotic Arishina → Fasting insulin levels
F-Biotic Arishina → Fasting insulin levels
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Evidence Tracker
12 tracked topics
Saved Studies
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on F-Biotic Arishina and Fasting Glucose, F-Biotic Arishina and Insulin Resistance.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies on F-Biotic Arishina
Contributes to F-Biotic Arishina evidence base.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies measuring Insulin Resistance
Measures Insulin Resistance as a key outcome.
All studies measuring lipid profiles
Measures lipid profiles as a key outcome.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
F-Biotic Arishina appears to improve Fasting blood sugar (FBS).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fasting blood sugar (FBS)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
F-Biotic Arishina appears to improve GLP-1.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
GLP-1
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
F-Biotic Arishina appears to improve Glucose iAUC (OGTT).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Glucose iAUC (OGTT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
F-Biotic Arishina appears to improve Quality of life.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Quality of life
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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