Resumen de Investigación
Analyzed using Evidence Intelligence™

Natural products may improve glycemic control in type 2 diabetes

Última actualización 12 de junio de 2026

Key finding

Blood glucose decreased by 0.71 mmol/L

This study investigated the potential of natural product-based treatments for type 2 diabetes and cardiovascular disease, finding significant reductions in various health markers.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study investigated the potential of natural product-based treatments for type 2 diabetes and cardiovascular disease, finding significant reductions in various health markers.

Clinical relevance

These findings are significant as they suggest that natural supplements could be effective adjuncts to traditional diabetes treatments. By potentially lowering blood glucose and cholesterol levels, these interventions may help reduce the risk of complications associated with type 2 diabetes and cardiovascular disease, offering new avenues for patient care.

Keep in mind

Effectiveness of individual interventions remains unclear. Lack of detailed p-values for many outcomes. Potential variability in participant responses.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Dharmsheel S, Satyam KK, Shivangi S, Desh DS. Natural Products for Glycemic Control and Cardiovascular Health in Type 2 Diabetes: A Systematic Review. World Journal of Diabetes. 2024. doi:10.4239/wjd.v15.i7.1603

Efectos Principales

Blood glucose levels decreased by 0.71 mmol/L.

HbA1c levels decreased significantly.

Systolic blood pressure decreased significantly.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to American ginseng, Bilberry extract, Flavanol-rich cocoa, and 5 more and Blood glucose, HbA1c, Systolic blood pressure, and 6 more.

Primary intervention

American ginseng

Primary outcomes

  • Blood glucose
  • HbA1c
  • Systolic blood pressure

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

14
Evidence pairs
14
Relationships
4
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

4

Related topics

14

Evidence pairs

979

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 14 evidence relationships
  • Includes primary outcome data
  • Linked to 4 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Relación de evidencia

Fish Oil Supplements and Adipokine and Angiogenic Markers

Evidencia relacionada

Relación de evidencia

Fish Oil Supplements and Fasting Glucose

Guardar evidencia

Relación de evidencia

Fish Oil Supplements and Inflammatory Markers

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Blood glucose

American ginseng → Blood glucose

American ginseng → Blood glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

HbA1c

American ginseng → HbA1c

American ginseng → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Systolic blood pressure

American ginseng → Systolic blood pressure

American ginseng → Systolic blood pressure

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

HbA1c

Bilberry extract → HbA1c

Bilberry extract → HbA1c

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 2 estudios
Add to Evidence Tracker

Insulin resistance

Flavanol-rich cocoa → Insulin resistance

Flavanol-rich cocoa → Insulin resistance

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Total cholesterol

Flavanol-rich cocoa → Total cholesterol

Flavanol-rich cocoa → Total cholesterol

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

C-reactive protein

Flaxseed oil and fish oil → C-reactive protein

Flaxseed oil and fish oil → C-reactive protein

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Fasting blood sugar (FBS)

Melissa officinalis capsules → Fasting blood sugar (FBS)

Melissa officinalis capsules → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 2 estudios
Add to Evidence Tracker

HbA1c

Melissa officinalis capsules → HbA1c

Melissa officinalis capsules → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Fasting blood sugar (FBS)

Nigella sativa oil → Fasting blood sugar (FBS)

Nigella sativa oil → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Triglycerides

Nigella sativa oil → Triglycerides

Nigella sativa oil → Triglycerides

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Endothelial function

Terminalia chebula → Endothelial function

Terminalia chebula → Endothelial function

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Total cholesterol

Vitamin E supplementation → Total cholesterol

Vitamin E supplementation → Total cholesterol

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Triglycerides

Vitamin E supplementation → Triglycerides

Vitamin E supplementation → Triglycerides

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

evidence suggest

La Evidencia Sugiere

  • Blood glucose levels decreased by 0.71 mmol/L.
  • HbA1c levels decreased significantly.
  • Systolic blood pressure decreased significantly.
keep in mind

Tener en Cuenta

  • Effectiveness of individual interventions remains unclear.
  • Lack of detailed p-values for many outcomes.
  • Potential variability in participant responses.
between the lines

Entre Líneas

  • Effectiveness of individual interventions remains unclear.
  • Lack of detailed p-values for many outcomes.
  • Potential variability in participant responses.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Bilberry extract and HbA1c, Melissa officinalis capsules and Fasting Glucose.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Fish Oil Supplements improve fasting glucose?

Moderate Evidence

Fish Oil Supplements appears to improve Fasting Glucose.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Fasting blood sugar (FBS)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only a small number of supporting studies are available.
  • Population details are unavailable.
2 supporting studiesUpdated: Jul 2026

Does Fish Oil Supplements improve adipokine and angiogenic markers?

Moderate Evidence

Fish Oil Supplements may improve Adipokine and Angiogenic Markers.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Triglycerides

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only a small number of supporting studies are available.
  • Population details are unavailable.
2 supporting studiesUpdated: Jul 2026

Does Fish Oil Supplements improve inflammatory markers?

Emerging Evidence

Fish Oil Supplements appears to improve Inflammatory Markers.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    C-reactive protein

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Bilberry extract improve HbA1c?

Moderate Evidence

Bilberry extract may improve HbA1c.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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