Última actualización 2 de julio de 2026
Key finding
Serum fasting blood glucose (p = 0.039) was significantly lower in the fish oil intervention group than in the corn oil control group at three months.
This study examined the effects of fish oil-derived omega-3 fatty acids on gut microbiota and serum lipid metabolites in individuals with Type 2 Diabetes Mellitus (T2DM). The fish oil group showed significant improvements in various metabolic markers compared to the corn oil control group.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Extended (5–20+ y)
Risk of bias
Some Concerns
Guarda este estudio en tu Evidence Tracker para encontrarlo facilmente cuando lo necesites.
Plain-language summary
A plain-language read of the study's main message and where it applies.
Study focus
This study examined the effects of fish oil-derived omega-3 fatty acids on gut microbiota and serum lipid metabolites in individuals with Type 2 Diabetes Mellitus (T2DM). The fish oil group showed significant improvements in various metabolic markers compared to the corn oil control group.
These findings highlight the potential of fish oil-derived omega-3 fatty acids as a therapeutic option for improving metabolic health in individuals with T2DM. By reducing fasting blood glucose and improving lipid profiles, omega-3 supplementation may contribute to better diabetes management and reduce the risk of cardiovascular complications associated with the disease.
The study was limited to a specific population with T2DM, which may affect generalizability. The duration of the intervention was relatively short at three months. Potential confounding factors were not fully explored.
Published in
Publication details and source links for this paper.
Jiayue X, Shiyu Y, Junhui Y, et al. Effects of Fish Oil-Derived Omega-3 Fatty Acids on Gut Microbiota and Serum Lipid Metabolites in T2DM. Nutrients. 2024;16(21):3755. doi:10.3390/nu16213755
Serum fasting blood glucose was significantly lower in the fish oil group (p = 0.039).
Glycosylated hemoglobin levels were significantly reduced in the fish oil group (p = 0.048).
Total cholesterol levels were significantly lower in the fish oil group (p < 0.001).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Fish oil and Abundance of Colidextribacter, Abundance of Desulfobacterota, Abundance of Haemophilus, and 12 more.
This study contributes evidence to
Primary intervention
Fish oil
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
15
Evidence pairs
319
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Guarda estudios y paginas de evidencia, organiza tu Evidence Tracker y manten en un solo lugar la investigacion que te importa.
Evidencia principal
Tema de evidencia
matched_outcome
Evidencia relacionada
Tema de evidencia
Seguir evidencia
Core evidence
The primary outcomes reported in this study.
Fish oil → Abundance of Colidextribacter
Fish oil → Abundance of Colidextribacter
Fish oil → Abundance of Desulfobacterota
Fish oil → Abundance of Desulfobacterota
Fish oil → Abundance of Lactobacillus
Fish oil → Abundance of Lactobacillus
Fish oil → Abundance of Limosilactobacillus
Fish oil → Abundance of Limosilactobacillus
Fish oil → Fasting Plasma Glucose (FPG)
Fish oil → Fasting Plasma Glucose (FPG)
Create a free account to save studies and evidence pages, organize your personal Evidence Tracker, and keep the research you care about in one place.
Today's Activity
Saved this study
Your free account becomes your personal diabetes evidence workspace.
Evidence Tracker
12 tracked topics
Saved Studies
48 studies
Research Notes
Coming Soon
Weekly Evidence Digest
Coming Soon
Keep this study in your Evidence Tracker so you can easily find it again whenever you need it.
Today's Activity
Saved this study
Your free account becomes your personal diabetes evidence workspace.
Evidence Tracker
12 tracked topics
Saved Studies
48 studies
Research Notes
Coming Soon
Weekly Evidence Digest
Coming Soon
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Fish oil and Abundance of Colidextribacter, Fish oil and Abundance of Desulfobacterota.
This study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Supplements
Supplements
Curated evidence collections and hubs this study is part of.
All studies measuring Abundance of Colidextribacter
Measures Abundance of Colidextribacter as a key outcome.
All studies measuring Abundance of Desulfobacterota
Measures Abundance of Desulfobacterota as a key outcome.
All studies measuring Adipokine and Angiogenic Markers
Measures Adipokine and Angiogenic Markers as a key outcome.
All studies on Fish oil
Contributes to Fish oil evidence base.
Latest published studies
Published within the last 2 years.
Jump to pre-filtered views in the evidence archive.
1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Fish oil appears to improve Abundance of Colidextribacter.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Abundance of Colidextribacter
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Fish oil appears to improve Abundance of Desulfobacterota.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Abundance of Desulfobacterota
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Fish oil appears to improve Abundance of Haemophilus.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Abundance of Haemophilus
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Fish oil appears to improve Abundance of Klebsiella.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Abundance of Klebsiella
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Next steps
Choose a next path through related evidence topics, archive views, and research summaries.
Follow the topics this study contributes to.
Open broader archive views for this relationship.
Read related research summaries.
Focused on evidence, not advertising.
Your data is always protected.
New studies added every day.