Resumen de Investigación
Analyzed using Evidence Intelligence™

Green tea extract may improve insulin resistance in type 2 diabetes patients

Última actualización 5 de julio de 2026

Key finding

Triglyceride decreased significantly from baseline.

This study evaluated the impact of green tea extract on glycemic and lipid profiles in patients with type 2 diabetes, finding significant improvements in several metabolic markers.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study's main message and where it applies.

Study focus

This study evaluated the impact of green tea extract on glycemic and lipid profiles in patients with type 2 diabetes, finding significant improvements in several metabolic markers.

Clinical relevance

The findings suggest that green tea extract could be a beneficial adjunct therapy for patients with type 2 diabetes, potentially aiding in the management of lipid levels and insulin resistance. This could lead to improved overall health outcomes and reduced risk of diabetes-related complications.

Keep in mind

The sample size and demographic diversity were not specified. The study did not assess long-term effects of green tea extract. Results may not be generalizable to all populations with type 2 diabetes.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Chia-Yu L, Chien-Jung H, Lin-Huang H, et al. The Effect of Green Tea Extract on Glycemic and Lipid Profiles in Patients with Type 2 Diabetes: A Randomized, Double-Blinded, Placebo-Controlled Trial. PLoS ONE. 2014;9(3):e91163. doi:10.1371/journal.pone.0091163

Efectos Principales

Triglycerides decreased significantly by 18.9 mg/dL in the green tea extract group.

HOMA-IR decreased from 5.4±3.9 to 3.5±2.0 in the therapeutic arm.

HDL-C increased significantly by 2.7 mg/dL in the green tea extract group.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Green tea extract and Adiponectin, Apolipoprotein A1, Apolipoprotein B100, and 4 more.

This study contributes evidence to

Primary intervention

Green tea extract

Primary outcomes

  • Adiponectin
  • Apolipoprotein A1
  • Apolipoprotein B100

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
0
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 50

0

Related topics

7

Evidence pairs

0

Related studies

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 0 direct semantic evidence topics

Core evidence

Study findings

The primary outcomes reported in this study.

Adiponectin

Green tea extract → Adiponectin

Green tea extract → Adiponectin

Evidence Intelligence™
ImpactScore™
100
Very Positive
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Apolipoprotein A1

Green tea extract → Apolipoprotein A1

Green tea extract → Apolipoprotein A1

Evidence Intelligence™
ImpactScore™
100
Very Positive
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Apolipoprotein B100

Green tea extract → Apolipoprotein B100

Green tea extract → Apolipoprotein B100

Evidence Intelligence™
ImpactScore™
100
Very Positive
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

GLP-1

Green tea extract → GLP-1

Green tea extract → GLP-1

Evidence Intelligence™
ImpactScore™
100
Very Positive
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HDL cholesterol

Green tea extract → HDL cholesterol

Green tea extract → HDL cholesterol

Evidence Intelligence™
ImpactScore™
100
Very Positive
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Insulin resistance

Green tea extract → Insulin resistance

Green tea extract → Insulin resistance

Evidence Intelligence™
ImpactScore™
100
Very Positive
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Triglycerides

Green tea extract → Triglycerides

Green tea extract → Triglycerides

Evidence Intelligence™
ImpactScore™
100
Very Positive
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

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Today's Activity

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Evidence Tracker

12 tracked topics

Saved Studies

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Research Notes

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Weekly Evidence Digest

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evidence suggest

La Evidencia Sugiere

  • Green tea extract led to a significant decrease in triglycerides.
  • HOMA-IR improved significantly in the therapeutic group.
  • HDL-C levels increased notably in patients taking green tea extract.
who this applies

A quién se aplica

  • Adults diagnosed with type 2 diabetes.
  • Patients looking for adjunct therapies to manage diabetes.
keep in mind

Tener en Cuenta

  • The study's findings are based on a specific population and may not apply universally.
  • Further research is needed to confirm long-term benefits and safety.
  • The placebo group did not show significant changes, indicating the need for careful interpretation of results.
between the lines

Entre Líneas

  • The sample size and demographic diversity were not specified.
  • The study did not assess long-term effects of green tea extract.
  • Results may not be generalizable to all populations with type 2 diabetes.

Save this study

Keep this study in your Evidence Tracker so you can easily find it again whenever you need it.

Today's Activity

Your Evidence Workspace

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Saved this study

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Evidence Tracker

12 tracked topics

Saved Studies

48 studies

Research Notes

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Coming Soon

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Green tea extract and Adipokine and Angiogenic Markers, Green tea extract and Apolipoprotein A1.

Relaciones de evidencia relacionadas

Explore in Evidence Archive

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Green tea extract improve adiponectin?

Emerging Evidence

Green tea extract appears to improve Adiponectin.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Adiponectin

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Green tea extract improve apolipoprotein a1?

Emerging Evidence

Green tea extract appears to improve Apolipoprotein A1.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Apolipoprotein A1

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Green tea extract improve apolipoprotein b100?

Emerging Evidence

Green tea extract appears to improve Apolipoprotein B100.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Apolipoprotein B100

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Green tea extract improve glp-1?

Emerging Evidence

Green tea extract appears to improve GLP-1.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    GLP-1

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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