Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Probiotics Improve Metabolic Outcomes in Post-GDM Women
Última actualización 9 de septiembre de 2026
Key finding
Fasting blood glucose level significantly decreased (mean difference -0.20 mmol/L; p = 0.0021).
This study investigated the effects of probiotics on metabolic outcomes in women with a history of gestational diabetes, finding significant improvements in fasting plasma glucose and other metabolic markers.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of probiotics on metabolic outcomes in women with a history of gestational diabetes, finding significant improvements in fasting plasma glucose and other metabolic markers.
Clinical relevance
The findings highlight the potential role of probiotics in improving metabolic health among women with a history of gestational diabetes, a group at risk for developing type 2 diabetes. By addressing metabolic dysfunction early, probiotics may offer a preventive strategy to reduce long-term health risks.
Keep in mind
Unclear effectiveness for some outcomes. Limited generalizability due to specific population. Potential confounding factors not measured.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Zubaidah H, Raja ARA, Hajar FA, et al. Probiotics Improve Metabolic Outcomes in Women with a History of Gestational Diabetes. Nutrients. 2022;14(18):3878. doi:10.3390/nu14183878
Efectos Principales
Fasting plasma glucose decreased by 0.20 mmol/L (p = 0.0021).
HbA1c levels differed significantly between groups (p < 0.05).
Total cholesterol levels differed significantly between groups (p < 0.05).
Bifidobacterium adolescentis increased significantly after supplementation.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Probiotics and C-reactive protein, Fasting Plasma Glucose (FPG), HbA1c, and 3 more.
This study contributes evidence to
Primary intervention
Probiotics
Primary outcomes
- C-reactive protein
- Fasting Plasma Glucose (FPG)
- HbA1c
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
6
Evidence pairs
6
Relationships
6
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
6
Related topics
6
Evidence pairs
2311
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 6 evidence relationships
- Includes primary outcome data
- Linked to 6 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Relación de evidencia
Probiotics and Synbiotics and Adipokine and Angiogenic Markers
Evidencia relacionada
Relación de evidencia
Probiotics and Synbiotics and HbA1c
Guardar evidencia
Relación de evidencia
Probiotics and Synbiotics and Fasting Glucose
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Fasting Plasma Glucose (FPG)
Probiotics → Fasting Plasma Glucose (FPG)
Probiotics → Fasting Plasma Glucose (FPG)
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerTotal number of medications used
Probiotics → Total number of medications used
Probiotics → Total number of medications used
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
La Evidencia Sugiere
- Fasting plasma glucose decreased by 0.20 mmol/L.
- Significant differences in HbA1c and cholesterol levels.
- Increased levels of Bifidobacterium adolescentis after probiotics.
A quién se aplica
- Women with a history of gestational diabetes.
- Participants in a randomized controlled trial.
Tener en Cuenta
- Results may not apply to all women with diabetes.
- Further research needed to confirm long-term effects.
- Study design limits generalizability to broader populations.
Entre Líneas
- Unclear effectiveness for some outcomes.
- Limited generalizability due to specific population.
- Potential confounding factors not measured.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Probiotics and Synbiotics and Fasting Glucose, Probiotics and Synbiotics and HbA1c.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Probiotics and Synbiotics → Fasting Glucose
Supplements
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
View evidenceSupplements
Probiotics and Synbiotics → HbA1c
Supplements
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
View evidenceSupplements
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Fasting Glucose Evidence Hub
All studies measuring Fasting Glucose
2 studies
outcome_hubMeasures Fasting Glucose as a key outcome.
HbA1c Evidence Hub
All studies measuring HbA1c
2 studies
outcome_hubMeasures HbA1c as a key outcome.
Probiotics and Synbiotics Evidence Hub
All studies on Probiotics and Synbiotics
2 studies
intervention_hubContributes to Probiotics and Synbiotics evidence base.
Adipokine and Angiogenic Markers Evidence Hub
All studies measuring Adipokine and Angiogenic Markers
1 studies
outcome_hubMeasures Adipokine and Angiogenic Markers as a key outcome.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Probiotics and Fasting Plasma Glucose (FPG)
Intervention: ProbioticsOutcome: Fasting Plasma Glucose (FPG)
2 results
All studies on Probiotics and HbA1c
Intervention: ProbioticsOutcome: HbA1c
2 results
All studies on Probiotics
Intervention: Probiotics
2 results
All studies measuring Fasting Plasma Glucose (FPG)
Outcome: Fasting Plasma Glucose (FPG)
2 results
All studies measuring HbA1c
Outcome: HbA1c
2 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Do Probiotics and Synbiotics improve adipokine and angiogenic markers?
Strong Evidence
Probiotics and Synbiotics may improve adipokine and angiogenic markers.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
Total cholesterol
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
- 2
Triglycerides
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 11 supporting studies with generally consistent results and a positive effect signal.
Do Probiotics and Synbiotics lower HbA1c?
Strong Evidence
Probiotics and Synbiotics appear to lower HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 13 supporting studies with consistent results and a positive effect signal.
Do Probiotics and Synbiotics improve fasting glucose?
Strong Evidence
Probiotics and Synbiotics appear to improve fasting glucose.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
Fasting Plasma Glucose (FPG)
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 14 supporting studies with generally consistent results and a positive effect signal.
Do Probiotics and Synbiotics improve inflammatory markers?
Strong Evidence
Probiotics and Synbiotics may improve inflammatory markers.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
C-reactive protein
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 6 supporting studies with generally consistent results and a positive effect signal.
Next steps
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