Resumen de Investigación
Analyzed using Evidence Intelligence™

Probiotics show no significant effect on glycemic control in diabetes

Última actualización 12 de julio de 2026

Key finding

HbA1c decreased by -0.44 (-0.66 to -0.22)

This study investigated the effects of probiotic supplementation on glycemic control in adults with type 2 diabetes. Results showed no statistically significant improvements in key glycemic markers.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Low Risk

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study investigated the effects of probiotic supplementation on glycemic control in adults with type 2 diabetes. Results showed no statistically significant improvements in key glycemic markers.

Clinical relevance

Understanding the potential role of probiotics in managing diabetes is important for developing effective dietary interventions. However, this study indicates that probiotic supplementation alone may not be sufficient to improve glycemic control in adults with type 2 diabetes, highlighting the need for comprehensive treatment strategies that include lifestyle changes and medication.

Keep in mind

No statistically significant changes in primary outcomes. Small sample size may limit generalizability. Short duration of the intervention may not capture long-term effects.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Xuchao P, Hong X, Ning G, et al. Probiotic Supplementation and Glycemic Control in Adults with Type 2 Diabetes: A Randomized Controlled Trial. Frontiers in Endocrinology. 2024;15:1440286. doi:10.3389/fendo.2024.1440286

Efectos Principales

HbA1c decreased by -0.44% in the probiotic group, but not statistically significant (P>0.05).

Fasting blood glucose decreased by -0.97 mmol/L in the probiotic group, but not statistically significant (P>0.05).

Body weight decreased by -3.43 kg in the probiotic group, but not statistically significant (P>0.05).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Probiotic beverage containing Lactobacillus and Body weight, Fasting blood sugar (FBS), Fasting insulin levels, and 4 more.

Primary intervention

Probiotic beverage containing Lactobacillus

Primary outcomes

  • Body weight
  • Fasting blood sugar (FBS)
  • Fasting insulin levels

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

3

Related topics

7

Evidence pairs

732

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Tema de evidencia

Glycemic Control

matched_outcome

Evidencia relacionada

Tema de evidencia

HbA1c Reduction

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Body weight

Probiotic beverage containing Lactobacillus → Body weight

Probiotic beverage containing Lactobacillus → Body weight

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Fasting blood sugar (FBS)

Probiotic beverage containing Lactobacillus → Fasting blood sugar (FBS)

Probiotic beverage containing Lactobacillus → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Fasting insulin levels

Probiotic beverage containing Lactobacillus → Fasting insulin levels

Probiotic beverage containing Lactobacillus → Fasting insulin levels

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

HbA1c

Probiotic beverage containing Lactobacillus → HbA1c

Probiotic beverage containing Lactobacillus → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Insulin resistance

Probiotic beverage containing Lactobacillus → Insulin resistance

Probiotic beverage containing Lactobacillus → Insulin resistance

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Total cholesterol

Probiotic beverage containing Lactobacillus → Total cholesterol

Probiotic beverage containing Lactobacillus → Total cholesterol

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Triglycerides

Probiotic beverage containing Lactobacillus → Triglycerides

Probiotic beverage containing Lactobacillus → Triglycerides

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Evidence Library

Build your evidence library

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evidence suggest

La Evidencia Sugiere

  • HbA1c decreased by -0.44% in the probiotic group, but not statistically significant.
  • Fasting blood glucose decreased by -0.97 mmol/L in the probiotic group, but not statistically significant.
  • Body weight decreased by -3.43 kg in the probiotic group, but not statistically significant.
who this applies

A quién se aplica

  • Adults diagnosed with type 2 diabetes.
  • Individuals seeking dietary interventions for glycemic control.
keep in mind

Tener en Cuenta

  • Results may not apply to all populations with diabetes.
  • The study did not measure long-term effects of probiotics.
  • Further research is needed to explore the role of probiotics in diabetes management.
between the lines

Entre Líneas

  • No statistically significant changes in primary outcomes.
  • Small sample size may limit generalizability.
  • Short duration of the intervention may not capture long-term effects.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Probiotic beverage containing Lactobacillus and Body Weight, Probiotic beverage containing Lactobacillus and Fasting Glucose.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Incluido en estas colecciones de evidencia

Curated evidence collections and hubs this study is part of.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Probiotic beverage containing Lactobacillus affect body weight?

Emerging Evidence

Current evidence does not show a clear benefit of Probiotic beverage containing Lactobacillus for Body weight.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Body weight

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Probiotic beverage containing Lactobacillus improve fasting blood sugar (fbs)?

Emerging Evidence

Current evidence does not show a clear benefit of Probiotic beverage containing Lactobacillus for Fasting blood sugar (FBS).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting blood sugar (FBS)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Probiotic beverage containing Lactobacillus improve fasting insulin levels?

Emerging Evidence

Current evidence does not show a clear benefit of Probiotic beverage containing Lactobacillus for Fasting insulin levels.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting insulin levels

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Probiotic beverage containing Lactobacillus improve HbA1c?

Emerging Evidence

Current evidence does not show a clear benefit of Probiotic beverage containing Lactobacillus for HbA1c.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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