Última actualización 6 de julio de 2026
Key finding
The mean FBG in the intervention group decreased by 21.52 mg/dL.
This study examined the effects of zinc supplementation on glycemic control and lipid profiles in newly diagnosed type 2 diabetes patients, finding significant reductions in fasting plasma glucose and cholesterol levels.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
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Plain-language summary
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Study focus
This study examined the effects of zinc supplementation on glycemic control and lipid profiles in newly diagnosed type 2 diabetes patients, finding significant reductions in fasting plasma glucose and cholesterol levels.
These findings suggest that zinc supplementation could be a beneficial adjunct therapy for managing glycemic control and lipid profiles in patients with newly diagnosed type 2 diabetes. Improved management of these parameters is crucial for reducing the risk of complications associated with diabetes, such as cardiovascular disease.
The study did not assess long-term effects of zinc supplementation. Sample size and demographic diversity may limit generalizability. No significant changes were observed in HDL, VLDL, or ESR.
Published in
Publication details and source links for this paper.
Alexander M, John RA, Gurpreet SC, et al. The Impact of Zinc Supplementation on Glycemic Control and Lipid Profiles in Newly Diagnosed Type 2 Diabetes Patients. Cureus. 2024;16(9):e69180. doi:10.7759/cureus.69180
Fasting Plasma Glucose decreased by 21.52 mg/dL
Postprandial blood glucose decreased by 47.53 mg/dL
LDL cholesterol decreased by 25.06 mg/dL
Triglycerides decreased by 22.2 mg/dL
Evidence network
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This study contributes evidence to Zinc supplementation and Fasting Plasma Glucose (FPG), Glucose iAUC (OGTT), HbA1c, and 3 more.
This study contributes evidence to
Primary intervention
Zinc supplementation
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
6
Evidence pairs
555
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
matched_outcome
Evidencia relacionada
Tema de evidencia
Guardar evidencia
Core evidence
The primary outcomes reported in this study.
Zinc supplementation → Fasting Plasma Glucose (FPG)
Zinc supplementation → Fasting Plasma Glucose (FPG)
Zinc supplementation → Glucose iAUC (OGTT)
Zinc supplementation → Glucose iAUC (OGTT)
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Zinc supplementation and Fasting Glucose, Zinc supplementation and Postprandial and OGTT Glucose.
This study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Curated evidence collections and hubs this study is part of.
All studies measuring Adipokine and Angiogenic Markers
Measures Adipokine and Angiogenic Markers as a key outcome.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies measuring Postprandial and OGTT Glucose
Measures Postprandial and OGTT Glucose as a key outcome.
All studies on Zinc supplementation
Contributes to Zinc supplementation evidence base.
Latest published studies
Published within the last 2 years.
Jump to pre-filtered views in Evidence Explorer.
1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Zinc supplementation appears to improve Fasting Plasma Glucose (FPG).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Zinc supplementation appears to improve Glucose iAUC (OGTT).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Glucose iAUC (OGTT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Zinc supplementation appears to improve HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Zinc supplementation appears to improve LDL cholesterol.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
LDL cholesterol
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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