Evidence Question

Does Metformin improve triglycerides?

Related to: Cardiometabolic Risk

Short answer

Metformin may worsen triglycerides or be associated with harm.

Evidence at a glance

Evidence strength
Moderate Evidence
Supporting research
2 studys
Randomized trials
2 trials

Why do we say this?

Across 2 randomized trials, findings are mixed and showed an effect on triglycerides with Metformin.

Context and limitations

Some evidence reported worsening or harm while other evidence found little or no effect.

  • Only a small number of supporting studies are available.

Explore the evidence

Supporting research

2 published studys