Evidence Question

Does Metformin improve Insulin sensitivity?

Related to: Insulin Resistance

Short answer

Metformin may improve Insulin sensitivity.

How the evidence connects

Each connection shows the published evidence classification for that intervention and outcome relationship.

Intervention

Metformin

Intervention

Strong
Positive
Mixed

4 studies · 4 RCTs

Outcome

Insulin sensitivity

Outcome

Why do we say this?

Some supporting studies report the observed direction, while others do not show the same pattern.

Explore the evidence