Research Summary
Analyzed using Evidence Intelligence™

Boscisucrophage improves glycemic control in resistant type 2 diabetes patients

Last updated July 18, 2026

Key finding

BSP significantly reduced fasting blood glucose concentration (p < 0.001).

The study evaluated the efficacy of Boscisucrophage in patients with Type 2 Diabetes who were resistant to oral antihyperglycemic drugs, finding significant reductions in fasting plasma glucose and HbA1c levels.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

The study evaluated the efficacy of Boscisucrophage in patients with Type 2 Diabetes who were resistant to oral antihyperglycemic drugs, finding significant reductions in fasting plasma glucose and HbA1c levels.

Clinical relevance

This study highlights a potential new treatment option for patients with Type 2 Diabetes who do not respond to conventional oral medications. By demonstrating significant improvements in key glycemic indicators, Boscisucrophage could offer a valuable alternative for managing blood sugar levels, ultimately improving patient outcomes and quality of life.

Keep in mind

The study design was observational, limiting causal inferences. Sample size and demographic details were not provided. Long-term effects and safety of Boscisucrophage remain unclear.

Published in

Journal Reference

Publication details and source links for this paper.

Bruno E, Amal E, Fahd AN, et al. Efficacy of Boscisucrophage in Type 2 Diabetes Patients Resistant to Oral Antihyperglycemic Drugs. Food Science & Nutrition. 2026;14(3):e71621. doi:10.1002/fsn3.71621

Main Effects

Boscisucrophage reduced fasting plasma glucose by 219.5 mg/dL (p < 0.001).

Boscisucrophage decreased HbA1c levels by 2.5% (p < 0.0001).

Boscisucrophage increased urinary glucose excretion.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Boscisucrophage (Boscia senegalensis extract) and AST, Alanine Aminotransferase (ALT), Change in functional symptoms of T2DM, and 4 more.

Primary intervention

Boscisucrophage (Boscia senegalensis extract)

Primary outcomes

  • AST
  • Alanine Aminotransferase (ALT)
  • Change in functional symptoms of T2DM

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

2

Related topics

7

Evidence pairs

555

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence topic

Glycemic Control

matched_outcome

Related evidence

Evidence topic

HbA1c Reduction

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Alanine Aminotransferase (ALT)

Boscisucrophage (Boscia senegalensis extract) → Alanine Aminotransferase (ALT)

Boscisucrophage (Boscia senegalensis extract) → Alanine Aminotransferase (ALT)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

AST

Boscisucrophage (Boscia senegalensis extract) → AST

Boscisucrophage (Boscia senegalensis extract) → AST

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Change in functional symptoms of T2DM

Boscisucrophage (Boscia senegalensis extract) → Change in functional symptoms of T2DM

Boscisucrophage (Boscia senegalensis extract) → Change in functional symptoms of T2DM

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Boscisucrophage (Boscia senegalensis extract) → Fasting Plasma Glucose (FPG)

Boscisucrophage (Boscia senegalensis extract) → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Boscisucrophage (Boscia senegalensis extract) → HbA1c

Boscisucrophage (Boscia senegalensis extract) → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Serum creatinine

Boscisucrophage (Boscia senegalensis extract) → Serum creatinine

Boscisucrophage (Boscia senegalensis extract) → Serum creatinine

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Urine glucose excretion (UGE)

Boscisucrophage (Boscia senegalensis extract) → Urine glucose excretion (UGE)

Boscisucrophage (Boscia senegalensis extract) → Urine glucose excretion (UGE)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Significant reduction in fasting plasma glucose by 219.5 mg/dL.
  • HbA1c levels decreased by 2.5%, indicating better long-term glucose control.
  • Increased urinary glucose excretion suggests enhanced glucose disposal.
who this applies

Who this applies to

  • Adults with Type 2 Diabetes resistant to oral antihyperglycemic drugs.
  • Patients seeking alternative treatments for glycemic control.
keep in mind

Keep in Mind

  • Results are based on a cohort study, which may not establish causality.
  • Findings may not be generalizable to all populations with diabetes.
  • Further research is needed to assess long-term safety and efficacy.
between the lines

Between the Lines

  • The study design was observational, limiting causal inferences.
  • Sample size and demographic details were not provided.
  • Long-term effects and safety of Boscisucrophage remain unclear.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Boscisucrophage (Boscia senegalensis extract) and Adipokine and Angiogenic Markers, Boscisucrophage (Boscia senegalensis extract) and AST.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Boscisucrophage (Boscia senegalensis extract) improve change in functional symptoms of t2dm?

Emerging Evidence

Boscisucrophage (Boscia senegalensis extract) appears to improve Change in functional symptoms of T2DM.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Change in functional symptoms of T2DM

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Boscisucrophage (Boscia senegalensis extract) improve fasting plasma glucose (fpg)?

Emerging Evidence

Boscisucrophage (Boscia senegalensis extract) appears to improve Fasting Plasma Glucose (FPG).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Boscisucrophage (Boscia senegalensis extract) improve HbA1c?

Emerging Evidence

Boscisucrophage (Boscia senegalensis extract) appears to improve HbA1c.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Boscisucrophage (Boscia senegalensis extract) improve ast?

Emerging Evidence

Current evidence does not show a clear benefit of Boscisucrophage (Boscia senegalensis extract) for AST.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    AST

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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