Research Summary
Analyzed using Evidence Intelligence™

Digital Health Program Improves Glycemic Control and Weight Loss

Last updated August 23, 2026

Key finding

Mean HbA1c went from 58.8 mmol/mol at baseline to 54.0 mmol/mol, representing a mean reduction of 4.78 mmol/mol (SD 4.60; t 31 =5.87; P <.001).

Low Carb Program digital health intervention for glycemic control and weight loss in adults with type 2 diabetes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

Non-randomized CT

Follow-up

Long-Term (1–5 y)

Risk of bias

High Risk

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

Low Carb Program digital health intervention for glycemic control and weight loss in adults with type 2 diabetes.

Clinical relevance

This study evaluated Low Carb Program digital health intervention for glycemic control and weight loss in adults with type 2 diabetes.

Keep in mind

Limitations were not clearly described in the extracted text.

Published in

Journal Reference

Publication details and source links for this paper.

Dina G, Ralf S, Yvonne B, Charlotte S, Simon T, David U. Real-World Outcomes of a Digital Health Intervention for Type 2 Diabetes: The Low Carb Program. JMIR Diabetes. 2021;6(3):e25751. doi:10.2196/25751

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Remote nutrition education on low-carbohydrate diet and Body weight, Engagement in lifestyle change program at 12 months, HbA1c.

Primary intervention

Remote nutrition education on low-carbohydrate diet

Primary outcomes

  • Body weight
  • Engagement in lifestyle change program at 12 months
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

3
Evidence pairs
3
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

2

Related topics

3

Evidence pairs

707

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 3 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Low-Carbohydrate Diet Education and HbA1c

Related evidence

Evidence relationship

Low-Carbohydrate Diet Education and Body Weight

Save evidence

Evidence topic

HbA1c Reduction

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Core evidence

Study findings

The primary outcomes reported in this study.

Body weight

Remote nutrition education on low-carbohydrate diet → Body weight

Remote nutrition education on low-carbohydrate diet → Body weight

Evidence Intelligence™
EvidenceScore™
54
Emerging
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Engagement in lifestyle change program at 12 months

Remote nutrition education on low-carbohydrate diet → Engagement in lifestyle change program at 12 months

Remote nutrition education on low-carbohydrate diet → Engagement in lifestyle change program at 12 months

Evidence Intelligence™
EvidenceScore™
54
Emerging
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Remote nutrition education on low-carbohydrate diet → HbA1c

Remote nutrition education on low-carbohydrate diet → HbA1c

Evidence Intelligence™
EvidenceScore™
67
Moderate
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Low-Carbohydrate Diet Education and HbA1c, Low-Carbohydrate Diet Education and Body Weight.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Low-Carbohydrate Diet Education improve HbA1c?

Strong Evidence

Low-Carbohydrate Diet Education appears to improve HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Moderate | EvidenceScore™ 67.0 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 18 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
18 supporting studiesUpdated: Aug 2026

Does Low-Carbohydrate Diet Education affect body weight?

Strong Evidence

Low-Carbohydrate Diet Education appears to improve Body Weight.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Body weight

    EvidenceScore™ Emerging | EvidenceScore™ 54.4 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 10 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
10 supporting studiesUpdated: Aug 2026

Does Remote nutrition education on low-carbohydrate diet improve engagement in lifestyle change program at 12 months?

Emerging Evidence

Remote nutrition education on low-carbohydrate diet appears to improve Engagement in lifestyle change program at 12 months.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Engagement in lifestyle change program at 12 months

    EvidenceScore™ Emerging | EvidenceScore™ 54.4 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026
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