Research Summary
Analyzed using Evidence Intelligence™

Dietary interventions improve glycemic control in pre-diabetic patients

Last updated July 18, 2026

Key finding

Weight decreased by 1.02 kg (95% CI: -1.96, -0.07; P = 0.017)

This randomized clinical trial assessed the impact of various dietary interventions on glycemic control in pre-diabetic patients, finding significant reductions in body weight, fasting blood sugar, and hemoglobin A1c.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This randomized clinical trial assessed the impact of various dietary interventions on glycemic control in pre-diabetic patients, finding significant reductions in body weight, fasting blood sugar, and hemoglobin A1c.

Clinical relevance

These findings are clinically significant as they demonstrate that specific dietary interventions can lead to meaningful improvements in glycemic control among pre-diabetic individuals. This could potentially reduce the risk of progressing to type 2 diabetes, highlighting the importance of dietary management in diabetes prevention strategies.

Keep in mind

Exact values for some outcomes were not provided. Effectiveness of all interventions remains unclear. Sample size and demographic details were not specified.

Published in

Journal Reference

Publication details and source links for this paper.

Yahya P, Amir S, Nayebali R, et al. The effects of dietary interventions on glycemic control in pre-diabetic patients: a randomized clinical trial. Diabetology & Metabolic Syndrome. 2025;17:319. doi:10.1186/s13098-025-01901-7

Main Effects

Body weight decreased by 1.02 kg (P = 0.017)

Fasting Blood Sugar decreased by 6.42 mg/dL (P = 0.026)

Hemoglobin A1c decreased by 0.27% (P = 0.028)

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Anti-Inflammatory Diet, Intermittent Fasting (IF), Low-carbohydrate diet and Body weight, Fasting blood sugar (FBS), HbA1c.

Primary intervention

Anti-Inflammatory Diet

Primary outcomes

  • Body weight
  • Fasting blood sugar (FBS)
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

9
Evidence pairs
9
Relationships
4
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

4

Related topics

9

Evidence pairs

1089

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 9 evidence relationships
  • Includes primary outcome data
  • Linked to 4 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Low-Carbohydrate Diet Education and HbA1c

Related evidence

Evidence relationship

Low-Carbohydrate Diet Education and Body Weight

Save evidence

Evidence relationship

Low-Carbohydrate Diet Education and Fasting Glucose

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Body weight

Anti-Inflammatory Diet → Body weight

Anti-Inflammatory Diet → Body weight

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting blood sugar (FBS)

Anti-Inflammatory Diet → Fasting blood sugar (FBS)

Anti-Inflammatory Diet → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Anti-Inflammatory Diet → HbA1c

Anti-Inflammatory Diet → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Body weight

Intermittent Fasting (IF) → Body weight

Intermittent Fasting (IF) → Body weight

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting blood sugar (FBS)

Intermittent Fasting (IF) → Fasting blood sugar (FBS)

Intermittent Fasting (IF) → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Intermittent Fasting (IF) → HbA1c

Intermittent Fasting (IF) → HbA1c

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 3 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 3 studies
Add to Evidence Tracker

Body weight

Low-carbohydrate diet → Body weight

Low-carbohydrate diet → Body weight

Evidence Intelligence™
EvidenceScore™
79
Strong
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 3 studies
Add to Evidence Tracker

Fasting blood sugar (FBS)

Low-carbohydrate diet → Fasting blood sugar (FBS)

Low-carbohydrate diet → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Low-carbohydrate diet → HbA1c

Low-carbohydrate diet → HbA1c

Evidence Intelligence™
EvidenceScore™
79
Strong
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 3 studies
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Body weight decreased significantly by 1.02 kg.
  • Fasting Blood Sugar levels reduced by 6.42 mg/dL.
  • Hemoglobin A1c decreased by 0.27%.
who this applies

Who this applies to

  • Adults diagnosed with pre-diabetes.
  • Individuals seeking dietary interventions for glycemic control.
keep in mind

Keep in Mind

  • Results may not be generalizable to all populations.
  • Long-term effects of dietary interventions were not assessed.
  • Further research is needed to clarify effectiveness across different diets.
between the lines

Between the Lines

  • Exact values for some outcomes were not provided.
  • Effectiveness of all interventions remains unclear.
  • Sample size and demographic details were not specified.

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Intermittent Fasting (IF) and HbA1c, Low-Carbohydrate Diet Education and Body Weight.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Low-Carbohydrate Diet Education improve HbA1c?

Strong Evidence

Low-Carbohydrate Diet Education appears to improve HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 78.6 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 4 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
4 supporting studiesUpdated: Jul 2026

Does Low-Carbohydrate Diet Education affect body weight?

Strong Evidence

Low-Carbohydrate Diet Education appears to improve Body Weight.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Body weight

    EvidenceScore™ Strong | EvidenceScore™ 78.6 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 3 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
3 supporting studiesUpdated: Jul 2026

Does Low-Carbohydrate Diet Education improve fasting glucose?

Moderate Evidence

Low-Carbohydrate Diet Education may improve Fasting Glucose.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Fasting blood sugar (FBS)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only a small number of supporting studies are available.
  • Population details are unavailable.
2 supporting studiesUpdated: Jul 2026

Does Intermittent Fasting (IF) improve HbA1c?

Strong Evidence

Intermittent Fasting (IF) appears to improve HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 79.0 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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