Research Summary
Analyzed using Evidence Intelligence™

Digital intervention improves medication adherence in Type 2 Diabetes patients

Last updated August 29, 2026

Key finding

Intervention effectiveness was significantly associated with positive changes in the underlying mechanisms of behaviour change (R² = 0.26, SE = 0.98, P = 0.00).

This study evaluated the effectiveness of the MAPS intervention on medication adherence in patients with Type 2 Diabetes, showing significant positive changes in adherence-related behaviors.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the effectiveness of the MAPS intervention on medication adherence in patients with Type 2 Diabetes, showing significant positive changes in adherence-related behaviors.

Clinical relevance

Improving medication adherence is crucial for managing Type 2 Diabetes effectively, as it can lead to better health outcomes and reduce the risk of complications. This study highlights a successful intervention that can be implemented in clinical settings to support patients in their treatment regimens.

Keep in mind

Effectiveness of the intervention remains unclear due to unspecified limitations in data interpretation. Potential biases in self-reported adherence behaviors could affect the validity of outcomes. Generalizability may be limited as the study focused on a specific population.

Published in

Journal Reference

Publication details and source links for this paper.

Aikaterini K, Charlotte AC, Venus M, James B, Simon E, Stephen S. Post-Trial Process Evaluation of a Digital Intervention to Improve Medication Adherence in Patients with Type 2 Diabetes. Frontiers in Public Health. 2021;9:806168. doi:10.3389/fpubh.2021.806168

Main Effects

Medication adherence behavior improved significantly, with a positive association to behavior change mechanisms.

Motivation to adhere to medication was supported and enhanced by the intervention.

Beliefs about the ability to adhere to medication improved, despite perceived burdens.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Medication Adherence for Patients Support (MAPS) and Improvement in ability to adhere to medication, Improvement in beliefs about ability to adhere to medication, Increased motivation to adhere to medication, and 2 more.

Primary intervention

Medication Adherence for Patients Support (MAPS)

Primary outcomes

  • Improvement in ability to adhere to medication
  • Improvement in beliefs about ability to adhere to medication
  • Increased motivation to adhere to medication

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

5
Evidence pairs
5
Relationships
0
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 50

0

Related topics

5

Evidence pairs

0

Related studies

Why it is useful

  • Contributes to 5 evidence relationships
  • Includes primary outcome data
  • Linked to 0 direct semantic evidence topics

Core evidence

Study findings

The primary outcomes reported in this study.

Improvement in ability to adhere to medication

Medication Adherence for Patients Support (MAPS) → Improvement in ability to adhere to medication

Medication Adherence for Patients Support (MAPS) → Improvement in ability to adhere to medication

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Improvement in beliefs about ability to adhere to medication

Medication Adherence for Patients Support (MAPS) → Improvement in beliefs about ability to adhere to medication

Medication Adherence for Patients Support (MAPS) → Improvement in beliefs about ability to adhere to medication

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Increased motivation to adhere to medication

Medication Adherence for Patients Support (MAPS) → Increased motivation to adhere to medication

Medication Adherence for Patients Support (MAPS) → Increased motivation to adhere to medication

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Pain measured using the Von Korff scale

Medication Adherence for Patients Support (MAPS) → Pain measured using the Von Korff scale

Medication Adherence for Patients Support (MAPS) → Pain measured using the Von Korff scale

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Self-reported medication adherence at 12 months

Medication Adherence for Patients Support (MAPS) → Self-reported medication adherence at 12 months

Medication Adherence for Patients Support (MAPS) → Self-reported medication adherence at 12 months

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • R² values of 0.26 and 0.59 indicate significant increases in adherence-related behaviors.
  • Participants reported improved motivation and ability to adhere to their medication.
  • Perceived risks of health complications decreased with enhanced medication adherence.
who this applies

Who this applies to

  • Adults diagnosed with Type 2 Diabetes.
  • Patients currently prescribed medication for diabetes management.
keep in mind

Keep in Mind

  • The study's findings may not be applicable to all demographics of diabetes patients.
  • Results are based on self-reported data, which may introduce bias.
  • Further research is needed to confirm long-term effectiveness and applicability in diverse populations.
between the lines

Between the Lines

  • Effectiveness of the intervention remains unclear due to unspecified limitations in data interpretation.
  • Potential biases in self-reported adherence behaviors could affect the validity of outcomes.
  • Generalizability may be limited as the study focused on a specific population.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Medication Adherence for Patients Support (MAPS) and Improvement in ability to adhere to medication, Medication Adherence for Patients Support (MAPS) and Improvement in beliefs about ability to adhere to medication.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Included in these evidence collections

Curated evidence collections and hubs this study is part of.

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Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

What evidence is available on Medication Adherence for Patients Support (MAPS) and improvement in ability to adhere to medication?

Emerging Evidence

Medication Adherence for Patients Support (MAPS) appears to improve improvement in ability to adhere to medication.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Improvement in ability to adhere to medication

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

What evidence is available on Medication Adherence for Patients Support (MAPS) and improvement in beliefs about ability to adhere to medication?

Emerging Evidence

Medication Adherence for Patients Support (MAPS) appears to improve improvement in beliefs about ability to adhere to medication.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Improvement in beliefs about ability to adhere to medication

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Medication Adherence for Patients Support (MAPS) improve increased motivation to adhere to medication?

Emerging Evidence

Medication Adherence for Patients Support (MAPS) appears to improve increased motivation to adhere to medication.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Increased motivation to adhere to medication

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Medication Adherence for Patients Support (MAPS) improve self-reported medication adherence at 12 months?

Emerging Evidence

Medication Adherence for Patients Support (MAPS) appears to improve self-reported medication adherence at 12 months.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Self-reported medication adherence at 12 months

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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