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Research Summary
Analyzed using Evidence Intelligence™

ICM improves quality of life in cancer patients without diabetes

Powered by the Dediabetes Evidence Intelligence™ framework

Last updated July 11, 2026

Key finding

DM patients (vs. non-DM) responded significantly less on drowsiness on ESAS (P = 0.047).

This study examined the impact of an Integrative Complementary Medicine (ICM) program on the quality of life in cancer patients with diabetes, revealing significant differences in drowsiness and emotional functioning.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study examined the impact of an Integrative Complementary Medicine (ICM) program on the quality of life in cancer patients with diabetes, revealing significant differences in drowsiness and emotional functioning.

Clinical relevance

Understanding how complementary medicine affects quality of life in cancer patients with diabetes is crucial for developing holistic treatment plans. These findings can guide healthcare providers in integrating supportive therapies to enhance patient well-being.

Keep in mind

Study design limitations may affect the generalizability of findings. Sample size and characteristics were not detailed, limiting broader applicability. Unmeasured confounders could influence the outcomes.

Published in

Journal Reference

Publication details and source links for this paper.

Sameer K, Orit G, Noah S, Nili S, Benjamin G, Eran B. Impact of Integrative Complementary Medicine on Quality of Life in Cancer Patients with Diabetes. Supportive Care in Cancer. 2026;34(4):335. doi:10.1007/s00520-026-10511-6

View DOIView on PubMedView on PMC

Main Effects

Diabetic patients reported significantly less drowsiness on the ESAS (P = 0.047).

Emotional functioning was significantly lower in diabetic patients on the EORTC (P = 0.017).

No improvement in fatigue was observed in the diabetic group.

Sleep quality concerns showed no improvement in the diabetic group.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Integrative Complementary Medicine (ICM) Program and Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS), Emotional Functioning as Measured by EORTC QLQ-C30, Fatigue on ESAS, and 1 more.

This study contributes evidence to

Intervention

Integrative Complementary Medicine (ICM) Program

Outcome

Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

Primary intervention

Integrative Complementary Medicine (ICM) Program

Primary outcomes

  • Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)
  • Emotional Functioning as Measured by EORTC QLQ-C30
  • Fatigue on ESAS

Primary intervention

Integrative Complementary Medicine (ICM) Program

Primary outcomes

Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)Emotional Functioning as Measured by EORTC QLQ-C30Fatigue on ESAS

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

4
Evidence pairs
4
Relationships
0
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 54

0

Related topics

4

Evidence pairs

0

Related studies

Why it is useful

  • Contributes to 4 evidence relationships
  • Includes primary outcome data
  • Linked to 0 direct semantic evidence topics

Core evidence

Study findings

The primary outcomes reported in this study.

Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

Integrative Complementary Medicine (ICM) Program → Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

Integrative Complementary Medicine (ICM) Program → Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Emotional Functioning as Measured by EORTC QLQ-C30

Integrative Complementary Medicine (ICM) Program → Emotional Functioning as Measured by EORTC QLQ-C30

Integrative Complementary Medicine (ICM) Program → Emotional Functioning as Measured by EORTC QLQ-C30

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fatigue on ESAS

Integrative Complementary Medicine (ICM) Program → Fatigue on ESAS

Integrative Complementary Medicine (ICM) Program → Fatigue on ESAS

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Sleep quality

Integrative Complementary Medicine (ICM) Program → Sleep quality

Integrative Complementary Medicine (ICM) Program → Sleep quality

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Diabetic patients had significantly lower drowsiness scores (P = 0.047).
  • Emotional functioning was significantly impacted in diabetic patients (P = 0.017).
  • No improvements in fatigue or sleep quality were found.
who this applies

Who this applies to

  • Cancer patients diagnosed with diabetes.
  • Individuals undergoing treatment for cancer.
  • Patients seeking complementary medicine options.
keep in mind

Keep in Mind

  • Results are based on a cohort study design, which may limit causal inferences.
  • Findings are specific to the population studied and may not apply to all cancer patients.
  • The lack of improvement in fatigue and sleep quality suggests the need for further research.
between the lines

Between the Lines

  • Study design limitations may affect the generalizability of findings.
  • Sample size and characteristics were not detailed, limiting broader applicability.
  • Unmeasured confounders could influence the outcomes.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

Powered by the Dediabetes Evidence Intelligence™ framework

This study contributes to evidence on Integrative Complementary Medicine (ICM) Program and Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS), Integrative Complementary Medicine (ICM) Program and Emotional Functioning as Measured by EORTC QLQ-C30.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Included in these evidence collections

Curated evidence collections and hubs this study is part of.

Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS) Evidence Hub

All studies measuring Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

1 studies
outcome_hub

Measures Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS) as a key outcome.

Emotional Functioning as Measured by EORTC QLQ-C30 Evidence Hub

All studies measuring Emotional Functioning as Measured by EORTC QLQ-C30

1 studies
outcome_hub

Measures Emotional Functioning as Measured by EORTC QLQ-C30 as a key outcome.

Integrative Complementary Medicine (ICM) Program Evidence Hub

All studies on Integrative Complementary Medicine (ICM) Program

1 studies
intervention_hub

Contributes to Integrative Complementary Medicine (ICM) Program evidence base.

Quality of Life Outcomes Evidence Hub

All studies measuring Quality of Life Outcomes

1 studies
outcome_hub

Measures Quality of Life Outcomes as a key outcome.

Recent Diabetes Research

Latest published studies

recency_collection

Published within the last 2 years.

Explore more in Evidence Explorer

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All studies on Integrative Complementary Medicine (ICM) Program and Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

Intervention: Integrative Complementary Medicine (ICM) ProgramOutcome: Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

1 results

All studies on Integrative Complementary Medicine (ICM) Program and Emotional Functioning as Measured by EORTC QLQ-C30

Intervention: Integrative Complementary Medicine (ICM) ProgramOutcome: Emotional Functioning as Measured by EORTC QLQ-C30

1 results

All studies on Integrative Complementary Medicine (ICM) Program

Intervention: Integrative Complementary Medicine (ICM) Program

1 results

All studies measuring Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

Outcome: Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

1 results

All studies measuring Emotional Functioning as Measured by EORTC QLQ-C30

Outcome: Emotional Functioning as Measured by EORTC QLQ-C30

1 results

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Integrative Complementary Medicine (ICM) Program improve fatigue on esas?

Emerging Evidence

Current evidence does not show a clear benefit of Integrative Complementary Medicine (ICM) Program for Fatigue on ESAS.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fatigue on ESAS

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
View Full Evidence

Does Integrative Complementary Medicine (ICM) Program improve sleep quality?

Emerging Evidence

Current evidence does not show a clear benefit of Integrative Complementary Medicine (ICM) Program for Sleep quality.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Sleep quality

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
View Full Evidence

Does Integrative Complementary Medicine (ICM) Program improve drowsiness measured using the edmonton symptom assessment scale (esas)?

Emerging Evidence

Integrative Complementary Medicine (ICM) Program may worsen Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS) or be associated with harm.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | moderate negative | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
View Full Evidence

Does Integrative Complementary Medicine (ICM) Program improve emotional functioning as measured by eortc qlq-c30?

Emerging Evidence

Integrative Complementary Medicine (ICM) Program may worsen Emotional Functioning as Measured by EORTC QLQ-C30 or be associated with harm.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Emotional Functioning as Measured by EORTC QLQ-C30

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | moderate negative | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
View Full Evidence
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All studies on Integrative Complementary Medicine (ICM) Program and Drowsiness measured using the Edmonton Symptom Assessment Scale (ESAS)All studies on Integrative Complementary Medicine (ICM) Program and Emotional Functioning as Measured by EORTC QLQ-C30All studies on Integrative Complementary Medicine (ICM) Program and Fatigue on ESASAll studies on Integrative Complementary Medicine (ICM) Program and Sleep quality

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