Research Summary
Analyzed using Evidence Intelligence™

Intermittent fasting improves glycemic control.

Last updated July 14, 2026

Key finding

HbA1c decreased from 8.2% ± 1.0% to 7.4% ± 0.8% (P < 0.001)

This study investigated the effects of intermittent fasting on glycemic control in adults with type 2 diabetes, finding significant improvements in several metabolic markers.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study investigated the effects of intermittent fasting on glycemic control in adults with type 2 diabetes, finding significant improvements in several metabolic markers.

Clinical relevance

These findings are clinically significant as they suggest that intermittent fasting could be a viable dietary intervention for improving glycemic control in individuals with type 2 diabetes. By effectively reducing key metabolic markers, this approach may help in managing diabetes and reducing the risk of complications associated with the disease.

Keep in mind

Limited sample size may affect generalizability. Short duration of the study may not capture long-term effects. Lack of diversity in the participant population.

Published in

Journal Reference

Publication details and source links for this paper.

Maarya MS, Muneza MF, Moosa MS, Mohammed ASA, Amaarah AF, Afeefa S. Intermittent fasting improves glycemic control in adults with type 2 diabetes. Journal of Pharmacy & Bioallied Sciences. 2025;17(Suppl 3):S2410-S2412. doi:10.4103/jpbs.jpbs_1582_24

Main Effects

HbA1c decreased from 8.2% to 7.4% (P < 0.001)

Fasting plasma glucose decreased from 160 mg/dL to 130 mg/dL (P < 0.001)

BMI decreased from 28.5 kg/m² to 26.9 kg/m² (P < 0.01)

Waist circumference decreased from 96.2 cm to 90.8 cm (P < 0.01)

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Intermittent Fasting (IF) and BMI, Fasting Plasma Glucose (FPG), HbA1c, and 2 more.

Primary intervention

Intermittent Fasting (IF)

Primary outcomes

  • BMI
  • Fasting Plasma Glucose (FPG)
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

5
Evidence pairs
5
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

3

Related topics

5

Evidence pairs

700

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 5 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

Weight Loss

matched_outcome

Related evidence

Evidence topic

Glycemic Control

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

BMI

Intermittent Fasting (IF) → BMI

Intermittent Fasting (IF) → BMI

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Intermittent Fasting (IF) → Fasting Plasma Glucose (FPG)

Intermittent Fasting (IF) → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

HbA1c

Intermittent Fasting (IF) → HbA1c

Intermittent Fasting (IF) → HbA1c

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 3 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 3 studies
Add to Evidence Tracker

Insulin resistance

Intermittent Fasting (IF) → Insulin resistance

Intermittent Fasting (IF) → Insulin resistance

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Waist circumference

Intermittent Fasting (IF) → Waist circumference

Intermittent Fasting (IF) → Waist circumference

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • HbA1c decreased by 0.8% (P < 0.001).
  • Fasting plasma glucose decreased by 30 mg/dL (P < 0.001).
  • BMI decreased by 1.6 kg/m² (P < 0.01).
who this applies

Who this applies to

  • Adults aged 18-65 with type 2 diabetes.
  • Individuals seeking dietary interventions for glycemic control.
keep in mind

Keep in Mind

  • Results may not apply to older adults or those with other health conditions.
  • Further research is needed to confirm long-term effects.
  • Individual responses to intermittent fasting may vary.
between the lines

Between the Lines

  • Limited sample size may affect generalizability.
  • Short duration of the study may not capture long-term effects.
  • Lack of diversity in the participant population.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Intermittent Fasting (IF) and HbA1c, Intermittent Fasting (IF) and Fasting Glucose.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Intermittent Fasting (IF) improve HbA1c?

Strong Evidence

Intermittent Fasting (IF) appears to improve HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 79.0 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Intermittent Fasting (IF) improve fasting plasma glucose (fpg)?

Moderate Evidence

Intermittent Fasting (IF) appears to improve Fasting Plasma Glucose (FPG).

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Intermittent Fasting (IF) affect bmi?

Emerging Evidence

Intermittent Fasting (IF) appears to improve BMI.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    BMI

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Intermittent Fasting (IF) improve insulin resistance?

Emerging Evidence

Intermittent Fasting (IF) appears to improve Insulin resistance.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Insulin resistance

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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