Research Summary
Analyzed using Evidence Intelligence™

isCGM use may decrease mean glucose in newly diagnosed T1DM adults

Last updated September 9, 2026

Key finding

The mean glucose levels changed from 7.03 mmol/l to 6.73 mmol/l in the intervention group, resulting in a significant glucose difference of −0.66 mmol/l.

This study evaluated the impact of intermittently scanned continuous glucose monitoring (isCGM) on glycemic control and fear of hypoglycemia in adults with newly diagnosed type 1 diabetes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Extended (5–20+ y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the impact of intermittently scanned continuous glucose monitoring (isCGM) on glycemic control and fear of hypoglycemia in adults with newly diagnosed type 1 diabetes.

Clinical relevance

Effective glycemic control is crucial for individuals with type 1 diabetes to prevent complications. The significant reduction in mean glucose levels with isCGM indicates its potential as a valuable tool for managing diabetes. However, the lack of impact on fear of hypoglycemia highlights the need for additional strategies to address psychological aspects of diabetes management.

Keep in mind

The study did not demonstrate significant changes in fear of hypoglycemia. The sample size and demographic details were not specified. The clinical significance of the findings may vary among individuals.

Published in

Journal Reference

Publication details and source links for this paper.

Jerzy H, Agata G, Marta W, et al. Impact of Initiating Intermittently Scanned Continuous Glucose Monitoring on Glycemic Control and Fear of Hypoglycemia in Adults with Newly Diagnosed Type 1 Diabetes. Frontiers in Endocrinology. 2025;15:1503891. doi:10.3389/fendo.2024.1503891

Main Effects

Mean glucose levels decreased significantly by -0.66 mmol/l (p=0.041) in the intervention group.

Time below 70 mg/dl changed insignificantly from 2.42% to 2.25% in the intervention group.

Fear of hypoglycemia showed no significant change between groups after 4 weeks.

Evidence network

How this study fits

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Evidence Context

This study contributes evidence to Continuous glucose monitoring and Fear of hypoglycemia (worry), Percentage of time spent below 70 mg/dL, Pre-meal mean glucose, and 1 more.

Primary intervention

Continuous glucose monitoring

Primary outcomes

  • Fear of hypoglycemia (worry)
  • Percentage of time spent below 70 mg/dL
  • Pre-meal mean glucose

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

4
Evidence pairs
4
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

3

Related topics

4

Evidence pairs

825

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 4 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Insulin Delivery Systems and CGM Time in Range

Related evidence

Evidence topic

Diabetes Technology

Save evidence

Evidence topic

CGM Time in Range

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Fear of hypoglycemia (worry)

Continuous glucose monitoring → Fear of hypoglycemia (worry)

Continuous glucose monitoring → Fear of hypoglycemia (worry)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Percentage of time spent below 70 mg/dL

Continuous glucose monitoring → Percentage of time spent below 70 mg/dL

Continuous glucose monitoring → Percentage of time spent below 70 mg/dL

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Pre-meal mean glucose

Continuous glucose monitoring → Pre-meal mean glucose

Continuous glucose monitoring → Pre-meal mean glucose

Evidence Intelligence™
EvidenceScore™
79
Strong
ImpactScore™
69
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 4 studies
Add to Evidence Tracker

Time in range

Continuous glucose monitoring → Time in range

Continuous glucose monitoring → Time in range

Evidence Intelligence™
EvidenceScore™
85
Strong
ImpactScore™
77
Positive
ConsistencyScore™
62
generally_consistent
Supporting studies: Based on 13 studies
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Mean glucose levels decreased by -0.66 mmol/l with isCGM (p=0.041).
  • Time below 70 mg/dl was not significantly different between groups.
  • Fear of hypoglycemia did not change significantly after 4 weeks.
who this applies

Who this applies to

  • Adults with newly diagnosed type 1 diabetes.
  • Individuals seeking to improve glycemic control.
keep in mind

Keep in Mind

  • Results may not be generalizable to all diabetes populations.
  • The psychological impact of diabetes management was not addressed.
  • Further research is needed to explore long-term effects of isCGM.
between the lines

Between the Lines

  • The study did not demonstrate significant changes in fear of hypoglycemia.
  • The sample size and demographic details were not specified.
  • The clinical significance of the findings may vary among individuals.

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Insulin Delivery Systems and CGM Time in Range, Insulin Delivery Systems and CGM Time in Range.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Insulin Delivery Systems improve CGM Time in Range?

Strong Evidence

Insulin Delivery Systems may improve CGM Time in Range.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Time in range

    EvidenceScore™ Strong | EvidenceScore™ 85.2 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study

  2. 2

    Pre-meal mean glucose

    EvidenceScore™ Strong | EvidenceScore™ 78.8 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

35 supporting studies

Does Continuous glucose monitoring affect fear of hypoglycemia (WORRY)?

Emerging Evidence

Current evidence does not show a clear effect of Continuous glucose monitoring on fear of hypoglycemia (WORRY).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fear of hypoglycemia (worry)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Continuous glucose monitoring improve percentage of time spent below 70 mg/dl?

Emerging Evidence

Current evidence does not show a clear benefit of Continuous glucose monitoring for percentage of time spent below 70 mg/dl.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Percentage of time spent below 70 mg/dL

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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