Last updated August 24, 2026
Key finding
After 3 months of lifestyle intervention, obese women with OSA reduced their weight by 4.8±2.7% (p<0.0001).
This study evaluated the effects of a lifestyle intervention on obese women with obstructive sleep apnea, finding significant weight reduction and improvements in metabolic parameters.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the effects of a lifestyle intervention on obese women with obstructive sleep apnea, finding significant weight reduction and improvements in metabolic parameters.
These findings highlight the potential of lifestyle interventions in managing obesity and metabolic health in women with obstructive sleep apnea. Effective weight management can lead to improved health outcomes and may reduce the severity of sleep apnea, enhancing overall quality of life.
Single-arm study limits generalizability Non-significant changes in AHI and ODI Potential unmeasured confounders affecting outcomes
Published in
Publication details and source links for this paper.
Luisa G, Carolina L, Gabriella R, et al. Effects of Lifestyle Intervention in Obese Women with Obstructive Sleep Apnea. PLoS ONE. 2013;8(4):e61382. doi:10.1371/journal.pone.0061382
Weight reduction of 4.8% (p<0.0001)
Significant increase in insulin sensitivity
Significant improvement in beta cell function
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Digital-based lifestyle intervention and Apnea Hypopnea Index (AHI), Beta-cell function, Fasting Plasma Glucose (FPG), and 4 more.
This study contributes evidence to
Primary intervention
Digital-based lifestyle intervention
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
3
Related topics
7
Evidence pairs
792
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence relationship
Related evidence
Evidence relationship
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Evidence relationship
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Core evidence
The primary outcomes reported in this study.
Digital-based lifestyle intervention → Apnea Hypopnea Index (AHI)
Digital-based lifestyle intervention → Apnea Hypopnea Index (AHI)
Digital-based lifestyle intervention → Beta-cell function
Digital-based lifestyle intervention → Beta-cell function
Digital-based lifestyle intervention → Fasting Plasma Glucose (FPG)
Digital-based lifestyle intervention → Fasting Plasma Glucose (FPG)
Digital-based lifestyle intervention → Initial weight reduction in non-achievers
Digital-based lifestyle intervention → Initial weight reduction in non-achievers
Digital-based lifestyle intervention → Insulin sensitivity
Digital-based lifestyle intervention → Insulin sensitivity
Digital-based lifestyle intervention → Minimum Oxygen Saturation Improvement
Digital-based lifestyle intervention → Minimum Oxygen Saturation Improvement
Digital-based lifestyle intervention → Oxygen Desaturation Index
Digital-based lifestyle intervention → Oxygen Desaturation Index
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Digital Lifestyle Interventions and Fasting Glucose, Digital Lifestyle Interventions and Apnea Hypopnea Index (AHI).
This study contributes to the evidence on the following intervention-outcome relationships.
Devices & Technology
Devices & Technology
Devices & Technology
Curated evidence collections and hubs this study is part of.
All studies on Digital Lifestyle Interventions
Contributes to Digital Lifestyle Interventions evidence base.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies measuring Apnea Hypopnea Index (AHI)
Measures Apnea Hypopnea Index (AHI) as a key outcome.
All studies measuring Initial weight reduction in non-achievers
Measures Initial weight reduction in non-achievers as a key outcome.
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2 results
1 results
2 results
2 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Digital Lifestyle Interventions may improve Fasting Glucose.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Limitations
Digital Lifestyle Interventions may improve Insulin Resistance.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Insulin sensitivity
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Limitations
Current evidence does not show a clear benefit of Digital Lifestyle Interventions for Beta-cell Function.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Beta-cell function
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Digital-based lifestyle intervention appears to improve Initial weight reduction in non-achievers.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Initial weight reduction in non-achievers
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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