Research Summary
Analyzed using Evidence Intelligence™

Mindfulness intervention may reduce depression and insulin resistance in at-risk adolescents

Last updated August 16, 2026

Key finding

Depression decreased from baseline-to-1-year within MBI with a Cohen's d = 0.68.

This pilot trial evaluated a mindfulness-based intervention for adolescents at risk for type 2 diabetes, finding significant reductions in depression symptoms and insulin resistance.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Long-Term (1–5 y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This pilot trial evaluated a mindfulness-based intervention for adolescents at risk for type 2 diabetes, finding significant reductions in depression symptoms and insulin resistance.

Clinical relevance

These findings are significant as they suggest that mindfulness-based interventions could be a valuable tool in managing mental health and metabolic risk factors in adolescents, potentially preventing the onset of type 2 diabetes. Addressing both psychological and physiological aspects of health is crucial in this vulnerable population.

Keep in mind

Small sample size limits generalizability. Short follow-up period may not capture long-term effects. No significant differences in some key health measures.

Published in

Journal Reference

Publication details and source links for this paper.

Lauren BS, Bernadette P, Shelly KA, et al. Mindfulness-Based Intervention for Adolescents at Risk for Type 2 Diabetes: A Randomized Controlled Pilot Trial. Frontiers in Psychology. 2019;10:1040. doi:10.3389/fpsyg.2019.01040

Main Effects

Depression symptoms decreased significantly in the MBI group with a Cohen's d of 0.68.

Insulin resistance decreased significantly in the MBI group with a Cohen's d of 0.73.

No significant differences were found between groups for mindfulness, adiposity, or BMI.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Digital storytelling behavioral intervention and Adiposity indices, BMI, Depression symptoms reduction, and 2 more.

Primary intervention

Digital storytelling behavioral intervention

Primary outcomes

  • Adiposity indices
  • BMI
  • Depression symptoms reduction

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

5
Evidence pairs
5
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 60

2

Related topics

5

Evidence pairs

425

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 5 evidence relationships
  • Includes primary outcome data
  • Linked to 1 direct semantic evidence topic

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Digital Lifestyle Interventions and Body Mass Index

Related evidence

Evidence relationship

Digital Lifestyle Interventions and Insulin Resistance

Save evidence

Evidence topic

Weight Loss

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Adiposity indices

Digital storytelling behavioral intervention → Adiposity indices

Digital storytelling behavioral intervention → Adiposity indices

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

BMI

Digital storytelling behavioral intervention → BMI

Digital storytelling behavioral intervention → BMI

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Depression symptoms reduction

Digital storytelling behavioral intervention → Depression symptoms reduction

Digital storytelling behavioral intervention → Depression symptoms reduction

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Insulin resistance

Digital storytelling behavioral intervention → Insulin resistance

Digital storytelling behavioral intervention → Insulin resistance

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Mindfulness

Digital storytelling behavioral intervention → Mindfulness

Digital storytelling behavioral intervention → Mindfulness

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Depression symptoms decreased by 14.17 points in the MBI group (p=0.03).
  • Insulin resistance decreased by 1.26 units in the MBI group (p<0.01).
  • No significant changes were observed in mindfulness, adiposity, or BMI.
who this applies

Who this applies to

  • Adolescents aged 12-18 at risk for type 2 diabetes.
  • Individuals experiencing depressive symptoms.
keep in mind

Keep in Mind

  • Results are based on a pilot study and require further validation.
  • Findings may not be applicable to all adolescents or those with different health conditions.
  • The study did not measure long-term outcomes beyond one year.
between the lines

Between the Lines

  • Small sample size limits generalizability.
  • Short follow-up period may not capture long-term effects.
  • No significant differences in some key health measures.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Digital Lifestyle Interventions and Body Mass Index, Digital Lifestyle Interventions and Adiposity indices.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Digital Lifestyle Interventions affect body mass index?

Strong Evidence

Digital Lifestyle Interventions may improve Body Mass Index.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    BMI

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is based on 5 supporting studies with generally consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
5 supporting studiesUpdated: Aug 2026

Does Digital Lifestyle Interventions improve insulin resistance?

Strong Evidence

Digital Lifestyle Interventions may improve Insulin Resistance.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    Insulin resistance

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
3 supporting studiesUpdated: Aug 2026

Does Digital storytelling behavioral intervention improve depression symptoms reduction?

Emerging Evidence

Digital storytelling behavioral intervention appears to improve Depression symptoms reduction.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Depression symptoms reduction

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026

Does Digital storytelling behavioral intervention improve adiposity indices?

Emerging Evidence

Current evidence does not show a clear benefit of Digital storytelling behavioral intervention for Adiposity indices.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Adiposity indices

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026
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