Research Summary

Analyzed using Evidence Intelligence™

Vitadio app improves glycemic control in type 2 diabetes patients

Key finding

Adjusted mean difference: -0.53%, SD 0.15, 95% CI -0.24 to -0.82; P <.001

This study evaluated the impact of the Vitadio digital health application on glycemic control in patients with Type 2 Diabetes Mellitus, finding significant improvements in several health metrics.

Evidence strength

Moderate confidence

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Some Concerns bias

Last updated July 8, 2026

Quick read

Study at a glance

The essential study design details in one scan.

Population

Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes

Intervention

Vitadio digital health application

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Primary outcome

Glycated hemoglobin (HbA1c)

Comparator

Control Group (CG)

Plain-language summary

What this paper says

A plain-language read of the study's main message and where it applies.

Study focus

This study evaluated the impact of the Vitadio digital health application on glycemic control in patients with Type 2 Diabetes Mellitus, finding significant improvements in several health metrics.

Clinical relevance

Effective management of Type 2 Diabetes is crucial for preventing complications. The significant improvements observed in HbA1c, weight, and self-care behaviors suggest that digital health applications like Vitadio could be valuable tools in diabetes management, potentially enhancing patient outcomes and quality of life.

Keep in mind

Limited generalizability due to specific population characteristics. Potential biases in self-reported data. Short duration of follow-up may not capture long-term effects.

Published in

Journal Reference

Publication details and source links for this paper.

Amaryllis M, Timm R, Tommy A, et al. Impact of the Digital Health Application Vitadio on Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial. Journal of Medical Internet Research. 2025;27:e68648. doi:10.2196/68648

View DOI View on PubMed View on PMC

Save this study and add notes to your research library.

Main Effects

HbA1c decreased by 0.8% in the intervention group (p = 0.001).

Body weight decreased significantly by 2.2 kg in the intervention group (p = 0.002).

BMI decreased significantly by 0.47 kg/m² in the intervention group (p = 0.001).

Systolic blood pressure decreased by 7.23 mmHg in the intervention group (p < 0.03).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Digital storytelling behavioral intervention and BMI, Body weight, Change in General Diet Self-Care Score, and 4 more.

This study contributes evidence to

Intervention

Digital storytelling behavioral intervention

Outcome

BMI

Evidence topic

Weight Loss

Primary intervention

Digital storytelling behavioral intervention

Primary outcomes

BMI
Body weight
Change in General Diet Self-Care Score

Evidence topics

Weight Loss HbA1c Reduction

Primary intervention

Digital storytelling behavioral intervention

Primary outcomes

BMI Body weight Change in General Diet Self-Care Score

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

Evidence pairs

Relationships

Evidence topics

contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 69

Why it is useful

Contributes to 7 evidence relationships
Includes primary outcome data
Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Digital storytelling behavioral intervention → Systolic blood pressure

Evidence profile

StrongDecreaseMetabolic Health

Unlock full evidence details

Unlock full evidence analysis

Create a free account to access effectiveness ratings, evidence strength and depth scores, consistency analysis, and direct links to all supporting studies.

Evidence Suggest

HbA1c levels decreased by 0.8% in the intervention group.
Participants lost an average of 2.2 kg with the app.
Self-care scores for diet improved significantly.

Who this applies to

Adults diagnosed with Type 2 Diabetes Mellitus.
Individuals seeking to improve glycemic control through digital health solutions.

Keep in Mind

Results may not apply to all demographics or diabetes types.
Further research is needed to confirm long-term benefits.
Self-reported measures may introduce variability in data accuracy.

Between the Lines

Limited generalizability due to specific population characteristics.
Potential biases in self-reported data.
Short duration of follow-up may not capture long-term effects.

Unlock Full Analysis

Create a free account to unlock the bias score, detailed effectiveness analysis, and clinical outcomes for this study.

Already have an account?

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Digital storytelling behavioral intervention and Stress, Digital storytelling behavioral intervention and Body Mass Index.

Related evidence relationships

Explore in Evidence Archive

This study contributes to the evidence on the following intervention-outcome relationships.

Digital storytelling behavioral interventionStress

Behavioral & Lifestyle

2 studies

Detailed evidence

Digital storytelling behavioral interventionBody Mass Index

Behavioral & Lifestyle

1 studies

Detailed evidence

Digital storytelling behavioral interventionBody Weight

Behavioral & Lifestyle

1 studies

Detailed evidence

Included in these evidence collections

Curated evidence collections and hubs this study is part of.

Digital storytelling behavioral intervention Evidence Hub

All studies on Digital storytelling behavioral intervention

2 studies

intervention_hub

Contributes to Digital storytelling behavioral intervention evidence base.

Stress Evidence Hub

All studies measuring Stress

2 studies

outcome_hub

Measures Stress as a key outcome.

Body Mass Index Evidence Hub

All studies measuring Body Mass Index

1 studies

outcome_hub

Measures Body Mass Index as a key outcome.

Body Weight Evidence Hub

All studies measuring Body Weight

1 studies

outcome_hub

Measures Body Weight as a key outcome.

Recent Diabetes Research

Latest published studies

recency_collection

Published within the last 2 years.

Generated from the study's connected evidence using Evidence Intelligence™.

Does Digital storytelling behavioral intervention improve stress?

Emerging Evidence

Digital storytelling behavioral intervention appears to improve Stress.

ConsensusScore™: Results are consistent across studies.

Ranked evidence signals

1
Stress
EvidenceScore™ Emerging | EvidenceScore™ 55.3 | strong positive | ConsensusScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

Only one supporting study is available.
Population details are unavailable.

View Full Evidence

Does Digital storytelling behavioral intervention improve change in general diet self-care score?

Emerging Evidence

Digital storytelling behavioral intervention appears to improve Change in General Diet Self-Care Score.

ConsensusScore™: Results are consistent across studies.

Ranked evidence signals

1
Change in General Diet Self-Care Score
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

Only one supporting study is available.
Population details are unavailable.

View Full Evidence

Does Digital storytelling behavioral intervention affect bmi?

Emerging Evidence

Digital storytelling behavioral intervention appears to improve BMI.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

1
BMI
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

Only one supporting study is available.
Consistency cannot yet be determined.
Population details are unavailable.

View Full Evidence

Does Digital storytelling behavioral intervention affect body weight?

Emerging Evidence

Digital storytelling behavioral intervention appears to improve Body weight.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

1
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

Only one supporting study is available.
Consistency cannot yet be determined.
Population details are unavailable.

View Full Evidence

Learn how Evidence Intelligence™ works

Next steps

Continue your research

Choose a next path through related evidence topics, archive views, and research summaries.

Evidence topics

Follow the topics this study contributes to.

Weight Loss Evidence Hub HbA1c Reduction Evidence Hub Diabetes Technology Evidence Hub

Explore in archive

Open broader archive views for this relationship.

All studies on Digital storytelling behavioral intervention and HbA1c All studies on Digital storytelling behavioral intervention and Stress All studies on Digital storytelling behavioral intervention and BMI All studies on Digital storytelling behavioral intervention and Body weight

Related research

Read related research summaries.

Newer diabetes drugs show stronger weight and blood sugar benefits in prediabetes AI virtual trials match real trial results for GLP-1 vs insulin in type 2 diabetes Dietary supplements may lower diabetes risk in prediabetes GLP-1 agonists reduce heart fat thickness in diabetes.Mediterranean ketogenic eating matched VLCKD for weight loss over 3 months

No ads. No tracking.

Focused on evidence, not advertising.

Secure & private

Your data is always protected.

Always up to date

New studies added every day.