Last updated September 2, 2026
Key finding
HbA1c decreased from 7.2% at baseline to 5.0% at the most recent follow-up.
This study explored the long-term medication-free remission of Type 2 diabetes in a South Asian male through a low-carbohydrate dietary intervention.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Extended (5–20+ y)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study explored the long-term medication-free remission of Type 2 diabetes in a South Asian male through a low-carbohydrate dietary intervention.
This study highlights the potential of dietary interventions in managing Type 2 diabetes, particularly in populations where traditional medication approaches may be less effective. It underscores the importance of personalized dietary strategies in achieving long-term health outcomes.
Single participant limits generalizability No control group for comparison Long-term effects beyond the study duration are unknown
Published in
Publication details and source links for this paper.
Shashikant I, Jasmeet K, Anup S, et al. Long-term Medication-Free Remission of Type 2 Diabetes in a South Asian Male: An N-of-1 Longitudinal Study. Frontiers in Nutrition. 2026;13:1718156. doi:10.3389/fnut.2026.1718156
HbA1c decreased from 7.2% to 5.0%
Lipoprotein(a) decreased from 43.4 mg/dL to 25.3 mg/dL
Continuous glucose monitoring showed >90% time-in-range
Evidence network
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This study contributes evidence to Low-carbohydrate dietary intervention and Bone mineral density (BMD), C-reactive protein, Coronary artery calcium score, and 4 more.
This study contributes evidence to
Primary intervention
Low-carbohydrate dietary intervention
Primary outcomes
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
5
Related topics
7
Evidence pairs
1348
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Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
Low-carbohydrate dietary intervention → Bone mineral density (BMD)
Low-carbohydrate dietary intervention → Bone mineral density (BMD)
Low-carbohydrate dietary intervention → C-reactive protein
Low-carbohydrate dietary intervention → C-reactive protein
Low-carbohydrate dietary intervention → Coronary artery calcium score
Low-carbohydrate dietary intervention → Coronary artery calcium score
Low-carbohydrate dietary intervention → lipoprotein(a)
Low-carbohydrate dietary intervention → lipoprotein(a)
Low-carbohydrate dietary intervention → Ophthalmic imaging
Low-carbohydrate dietary intervention → Ophthalmic imaging
Low-carbohydrate dietary intervention → Time in range
Low-carbohydrate dietary intervention → Time in range
Evidence Library
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Low-carbohydrate dietary intervention and Bone Mineral Density, Low-carbohydrate dietary intervention and Inflammatory Markers.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Bone Mineral Density
Measures Bone Mineral Density as a key outcome.
All studies measuring Inflammatory Markers
Measures Inflammatory Markers as a key outcome.
All studies on Low-carbohydrate dietary intervention
Contributes to Low-carbohydrate dietary intervention evidence base.
Latest published studies
Published within the last 2 years.
Jump to pre-filtered views in Evidence Explorer.
1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Low-carbohydrate dietary intervention appears to improve coronary artery calcium score.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Coronary artery calcium score
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Low-carbohydrate dietary intervention appears to lower HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Low-carbohydrate dietary intervention appears to improve ophthalmic imaging.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Ophthalmic imaging
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Low-carbohydrate dietary intervention appears to improve time in range.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Time in range
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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