Last updated September 4, 2026
Key finding
Prevalence of exclusive breastfeeding did not differ between neonates with and without hypoglycemia (p = 0.51).
This study examined the impact of neonatal hypoglycemia on breastfeeding outcomes in women with Type 2 diabetes, finding no significant differences in breastfeeding practices.
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EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
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Study focus
This study examined the impact of neonatal hypoglycemia on breastfeeding outcomes in women with Type 2 diabetes, finding no significant differences in breastfeeding practices.
Understanding the relationship between neonatal hypoglycemia and breastfeeding outcomes is crucial for healthcare providers managing women with Type 2 diabetes. These findings suggest that concerns about breastfeeding may not need to be heightened in cases of neonatal hypoglycemia, allowing for more focused support for mothers in this population.
Limited sample size may affect generalizability. Study focused only on women with Type 2 diabetes, limiting applicability to other populations. Potential unmeasured confounders could influence breastfeeding outcomes.
Published in
Publication details and source links for this paper.
Daniella R, Marni J, Minhazur S, et al. Impact of Neonatal Hypoglycemia on Breastfeeding Outcomes in Women with Type 2 Diabetes: A Secondary Analysis. American journal of perinatology. 2026:10.1055/a-2827-0515. doi:10.1055/a-2827-0515
Prevalence of exclusive breastfeeding did not differ between neonates with and without hypoglycemia (p = 0.51).
Prevalence of partial breastfeeding was similar for both groups (p = 0.51).
The prevalence of not breastfeeding showed no significant difference (p = 0.51).
Average time to breastfeeding cessation was 2.6 to 2.8 weeks, with no significant difference (p = 0.76).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Metformin and Prevalence of exclusive breastfeeding, Prevalence of not breastfeeding, Proportion of participants developing diabetes, and 1 more.
This study contributes evidence to
Primary intervention
Metformin
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
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3
Related topics
4
Evidence pairs
472
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
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Evidence topic
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Evidence topic
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Core evidence
The primary outcomes reported in this study.
Metformin → Prevalence of exclusive breastfeeding
Metformin → Prevalence of exclusive breastfeeding
Metformin → Prevalence of not breastfeeding
Metformin → Prevalence of not breastfeeding
Metformin → Proportion of participants developing diabetes
Metformin → Proportion of participants developing diabetes
Metformin → Time to breastfeeding cessation
Metformin → Time to breastfeeding cessation
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Metformin Therapies and Prevalence of exclusive breastfeeding, Metformin Therapies and Prevalence of not breastfeeding.
This study contributes to the evidence on the following intervention-outcome relationships.
Curated evidence collections and hubs this study is part of.
All studies on Metformin Therapies
Contributes to Metformin Therapies evidence base.
All studies measuring Prevalence of exclusive breastfeeding
Measures Prevalence of exclusive breastfeeding as a key outcome.
All studies measuring Prevalence of not breastfeeding
Measures Prevalence of not breastfeeding as a key outcome.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Metformin Therapies may reduce diabetes incidence and prevention.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Proportion of participants developing diabetes
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Current evidence does not show a clear benefit of Metformin for prevalence of exclusive breastfeeding.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Prevalence of exclusive breastfeeding
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Metformin for prevalence of not breastfeeding.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Prevalence of not breastfeeding
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Metformin for time to breastfeeding cessation.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Time to breastfeeding cessation
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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