Last updated September 12, 2026
Key finding
The SUGAR Handshake was shown to reduce the rate and incidence of hypoglycaemia significantly.
The SUGAR Handshake intervention effectively reduced hypoglycaemic episodes in elderly individuals with type 2 diabetes mellitus.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
Save research, organize studies, and quickly find important evidence again.
Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
The SUGAR Handshake intervention effectively reduced hypoglycaemic episodes in elderly individuals with type 2 diabetes mellitus.
Hypoglycaemia is a serious concern for elderly patients with diabetes, as it can lead to severe health complications and decreased quality of life. By demonstrating that the SUGAR Handshake intervention can significantly reduce the incidence of hypoglycaemia, this study highlights a practical approach to improving the safety and management of diabetes in this vulnerable population.
Effectiveness data were unclear for some outcomes. The study's generalizability may be limited due to the specific population studied. Sample size and duration of follow-up may affect the robustness of findings.
Published in
Publication details and source links for this paper.
Huda YA, Helen MA, Richard AP, Keivan A. The SUGAR Handshake: A pharmacist-led educational intervention to prevent hypoglycaemia in elderly people with type 2 diabetes mellitus (T2DM). BMC Geriatrics. 2025;25:753. doi:10.1186/s12877-025-06361-2
The SUGAR Handshake reduced the total number of hypoglycaemic episodes by 1.5 episodes (p=0.002).
The intervention decreased the incidence of any hypoglycaemia by 0.8 episodes (p=0.01).
Hypoglycaemia-free survival improved by 30 days (p=0.005).
There was no change in fasting hyperglycaemia incidence (0 episodes, p=0.45).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to SUGAR Handshake and Fasting hyperglycaemia requiring therapy adjustment, Hypoglycemia Fear Survey Score, Incidence of hypoglycaemia, and 1 more.
This study contributes evidence to
Primary intervention
SUGAR Handshake
Primary outcomes
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
0
Related topics
4
Evidence pairs
0
Related studies
Core evidence
The primary outcomes reported in this study.
SUGAR Handshake → Fasting hyperglycaemia requiring therapy adjustment
SUGAR Handshake → Fasting hyperglycaemia requiring therapy adjustment
SUGAR Handshake → Hypoglycemia Fear Survey Score
SUGAR Handshake → Hypoglycemia Fear Survey Score
SUGAR Handshake → Incidence of hypoglycaemia
SUGAR Handshake → Incidence of hypoglycaemia
SUGAR Handshake → Number of hypoglycaemic episodes
SUGAR Handshake → Number of hypoglycaemic episodes
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on SUGAR Handshake and Fasting hyperglycaemia requiring therapy adjustment, SUGAR Handshake and Number of hypoglycaemic episodes.
This study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Behavioral & Lifestyle
Curated evidence collections and hubs this study is part of.
All studies measuring Fasting hyperglycaemia requiring therapy adjustment
Measures Fasting hyperglycaemia requiring therapy adjustment as a key outcome.
All studies measuring Number of hypoglycaemic episodes
Measures Number of hypoglycaemic episodes as a key outcome.
All studies on SUGAR Handshake
Contributes to SUGAR Handshake evidence base.
Latest published studies
Published within the last 2 years.
Jump to pre-filtered views in Evidence Explorer.
1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
SUGAR Handshake appears to reduce incidence of hypoglycaemia.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Incidence of hypoglycaemia
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
SUGAR Handshake appears to affect number of hypoglycaemic episodes.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Number of hypoglycaemic episodes
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of SUGAR Handshake for fasting hyperglycaemia requiring therapy adjustment.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fasting hyperglycaemia requiring therapy adjustment
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
SUGAR Handshake may have an unfavorable effect on hypoglycemia fear survey score or be associated with harm.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Hypoglycemia Fear Survey Score
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | moderate negative | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Next steps
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Open broader Evidence Explorer views for this relationship.
Read related research summaries.
Focused on evidence, not advertising.
Your data is always protected.
New studies added every day.
