Research Summary
Analyzed using Evidence Intelligence™

Probiotic supplement improves glycemic control in type 2 diabetes

Key finding

HbA1c decreased by 0.3%.

This study investigated the effects of a probiotic nutritional supplement on glycemic control in type 2 diabetes patients, revealing mixed results.

Evidence strength

Moderate confidence

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Some Concerns bias
Last updated July 6, 2026

Quick read

Study at a glance

The essential study design details in one scan.

Population

Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes

Intervention

BeaT-2/Sugarburner, Placebo

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Primary outcome

HbA1c

Comparator

Placebo

Plain-language summary

What this paper says

A plain-language read of the study's main message and where it applies.

Study focus

This study investigated the effects of a probiotic nutritional supplement on glycemic control in type 2 diabetes patients, revealing mixed results.

Clinical relevance

Understanding the role of probiotics in managing type 2 diabetes could offer new therapeutic options for patients struggling with glycemic control. If proven effective, such supplements could enhance existing treatment strategies, potentially leading to better health outcomes.

Keep in mind

Limited sample size may affect generalizability. Inconsistent results across different outcomes. Lack of long-term follow-up data.

Published in

Journal Reference

Publication details and source links for this paper.

Andreas P, Pamela C, Mina RH, et al. The impact of a probiotic nutritional supplement on glycemic control in patients with type 2 diabetes: A randomized controlled trial. Nutrition and Metabolic Insights. 2026;19:11786388251413658. doi:10.1177/11786388251413658

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Main Effects

HbA1c decreased by 0.3% (p=0.05)

Fasting plasma glucose decreased by 14% (p=0.05)

Insulin decreased by 17% (p=0.05)

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to BeaT-2/Sugarburner and Adiponectin, C-reactive protein, Fasting Plasma Glucose (FPG), and 4 more.

Primary intervention

BeaT-2/Sugarburner

Primary outcomes

  • Adiponectin
  • C-reactive protein
  • Fasting Plasma Glucose (FPG)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

3

Related topics

7

Evidence pairs

298

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Core evidence

Study findings

The primary outcomes reported in this study.

StrongIncrease

Adiponectin

BeaT-2/Sugarburner → Adiponectin

BeaT-2/Sugarburner → Adiponectin

Evidence profile

StrongIncreaseMetabolic Health
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StrongDecrease

C-reactive protein

BeaT-2/Sugarburner → C-reactive protein

BeaT-2/Sugarburner → C-reactive protein

Evidence profile

StrongDecreaseMetabolic Health
Unlock full evidence details
StrongDecrease

Fasting Plasma Glucose (FPG)

BeaT-2/Sugarburner → Fasting Plasma Glucose (FPG)

BeaT-2/Sugarburner → Fasting Plasma Glucose (FPG)

Evidence profile

StrongDecreaseGlycemic Control
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StrongDecrease

HbA1c

BeaT-2/Sugarburner → HbA1c

BeaT-2/Sugarburner → HbA1c

Evidence profile

StrongDecreaseGlycemic Control
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StrongDecrease

Insulin

BeaT-2/Sugarburner → Insulin

BeaT-2/Sugarburner → Insulin

Evidence profile

StrongDecreaseGlycemic Control
Unlock full evidence details
StrongDecrease

Insulin resistance

BeaT-2/Sugarburner → Insulin resistance

BeaT-2/Sugarburner → Insulin resistance

Evidence profile

StrongDecreaseMetabolic Health
Unlock full evidence details
StrongDecrease

Intact proinsulin

BeaT-2/Sugarburner → Intact proinsulin

BeaT-2/Sugarburner → Intact proinsulin

Evidence profile

StrongDecreaseGlycemic Control
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evidence suggest

Evidence Suggest

  • HbA1c showed a significant decrease of 0.3%.
  • Fasting plasma glucose decreased by 14%.
  • Insulin levels decreased by 17%.
who this applies

Who this applies to

  • Adults diagnosed with type 2 diabetes.
  • Patients seeking alternative or complementary treatments.
keep in mind

Keep in Mind

  • Results may not apply to all diabetes patients.
  • Further research is needed to confirm findings.
  • Variability in outcomes suggests a complex relationship.
between the lines

Between the Lines

  • Limited sample size may affect generalizability.
  • Inconsistent results across different outcomes.
  • Lack of long-term follow-up data.

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on BeaT-2/Sugarburner and Adipokine and Angiogenic Markers, BeaT-2/Sugarburner and Inflammatory Markers.

Related evidence relationships

Explore in Evidence Archive

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does BeaT-2/Sugarburner improve adiponectin?

Emerging Evidence

BeaT-2/Sugarburner appears to improve Adiponectin.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Adiponectin

    EvidenceScore™ Emerging | EvidenceScore™ 50.5 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does BeaT-2/Sugarburner improve c-reactive protein?

Emerging Evidence

BeaT-2/Sugarburner appears to improve C-reactive protein.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    C-reactive protein

    EvidenceScore™ Emerging | EvidenceScore™ 50.5 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does BeaT-2/Sugarburner improve fasting plasma glucose (fpg)?

Emerging Evidence

BeaT-2/Sugarburner appears to improve Fasting Plasma Glucose (FPG).

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 50.5 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does BeaT-2/Sugarburner improve HbA1c?

Emerging Evidence

BeaT-2/Sugarburner appears to improve HbA1c.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 50.5 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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