Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerResearch Summary
Analyzed using Evidence Intelligence™
Replacing Sucrose with Sucralose Shows Little Effect on Glycemia
Last updated September 12, 2026
Key finding
There was a small but significant reduction in BW (−0.5 kg [95% CI −1.0, −0.1]; p = 0.02)
This study evaluated the impact of substituting sucrose with sucralose in coffee/tea on glycemic control in individuals with type 2 diabetes. It found significant reductions in body weight, BMI, and waist circumference.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the impact of substituting sucrose with sucralose in coffee/tea on glycemic control in individuals with type 2 diabetes. It found significant reductions in body weight, BMI, and waist circumference.
Clinical relevance
These findings suggest that dietary modifications, such as using sucralose instead of sucrose, could be beneficial for weight management in people with type 2 diabetes. While glycemic control remained stable, the reduction in body weight and waist circumference may lead to improved overall health and reduced risk of diabetes-related complications.
Keep in mind
The study did not observe changes in HbA1c levels. Results may not be generalizable to all populations with diabetes. The sample size and duration of the study were not specified.
Published in
Journal Reference
Publication details and source links for this paper.
Viswanathan M, Valangaiman SM, Kuzhandaivelu A, et al. Effect of Replacing Sucrose with Sucralose in Coffee/Tea on Glycemic Control in Type 2 Diabetes: A Randomized Controlled Trial. Diabetes Therapy. 2024;15(9):2061-2077. doi:10.1007/s13300-024-01622-6
Main Effects
Body weight decreased by −0.5 kg (p = 0.02).
BMI decreased by −0.2 kg/m² (p = 0.03).
Waist circumference decreased by −0.8 cm (p = 0.002).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Sucralose substitution in coffee/tea and BMI, Body weight, Carbohydrate intake, and 6 more.
This study contributes evidence to
Primary intervention
Sucralose substitution in coffee/tea
Primary outcomes
- BMI
- Body weight
- Carbohydrate intake
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
9
Evidence pairs
9
Relationships
5
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
5
Related topics
9
Evidence pairs
1765
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 9 evidence relationships
- Includes primary outcome data
- Linked to 5 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
Weight Loss
matched_outcome
Related evidence
Evidence topic
Body Composition
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Body weight
Sucralose substitution in coffee/tea → Body weight
Sucralose substitution in coffee/tea → Body weight
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerChange in Visceral Adiposity Index
Sucralose substitution in coffee/tea → Change in Visceral Adiposity Index
Sucralose substitution in coffee/tea → Change in Visceral Adiposity Index
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerGlycemia risk index
Sucralose substitution in coffee/tea → Glycemia risk index
Sucralose substitution in coffee/tea → Glycemia risk index
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Trackerlipid accumulation product
Sucralose substitution in coffee/tea → lipid accumulation product
Sucralose substitution in coffee/tea → lipid accumulation product
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerUPF percentage contribution to total energy intake at follow-up
Sucralose substitution in coffee/tea → UPF percentage contribution to total energy intake at follow-up
Sucralose substitution in coffee/tea → UPF percentage contribution to total energy intake at follow-up
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerWaist circumference
Sucralose substitution in coffee/tea → Waist circumference
Sucralose substitution in coffee/tea → Waist circumference
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerCarbohydrate intake
Sucralose substitution in coffee/tea → Carbohydrate intake
Sucralose substitution in coffee/tea → Carbohydrate intake
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Library
Build your evidence library
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Evidence Suggest
- Significant weight loss of −0.5 kg was observed (p = 0.02).
- Waist circumference reduced by −0.8 cm (p = 0.002).
- Improvements in dietary intake metrics were noted (p < 0.0001).
Who this applies to
- Adults diagnosed with type 2 diabetes.
- Individuals seeking to manage weight through dietary changes.
Keep in Mind
- The study's findings are limited to the specific population studied.
- Long-term effects of sucralose substitution were not evaluated.
- Further research is needed to explore the implications for glycemic control.
Between the Lines
- The study did not observe changes in HbA1c levels.
- Results may not be generalizable to all populations with diabetes.
- The sample size and duration of the study were not specified.
Evidence Library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Sucralose substitution in coffee/tea and Body Mass Index, Sucralose substitution in coffee/tea and Body Weight.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Sucralose substitution in coffee/tea → Body Mass Index
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceDiet and Nutrition
Sucralose substitution in coffee/tea → Body Weight
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceDiet and Nutrition
Sucralose substitution in coffee/tea → lipid accumulation product
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Body Mass Index Evidence Hub
All studies measuring Body Mass Index
1 studies
outcome_hubMeasures Body Mass Index as a key outcome.
Body Weight Evidence Hub
All studies measuring Body Weight
1 studies
outcome_hubMeasures Body Weight as a key outcome.
lipid accumulation product Evidence Hub
All studies measuring lipid accumulation product
1 studies
outcome_hubMeasures lipid accumulation product as a key outcome.
Sucralose substitution in coffee/tea Evidence Hub
All studies on Sucralose substitution in coffee/tea
1 studies
intervention_hubContributes to Sucralose substitution in coffee/tea evidence base.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Sucralose substitution in coffee/tea and BMI
Intervention: Sucralose substitution in coffee/teaOutcome: BMI
1 results
All studies on Sucralose substitution in coffee/tea and Body weight
Intervention: Sucralose substitution in coffee/teaOutcome: Body weight
1 results
All studies on Sucralose substitution in coffee/tea
Intervention: Sucralose substitution in coffee/tea
1 results
All studies measuring BMI
Outcome: BMI
1 results
All studies measuring Body weight
Outcome: Body weight
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Sucralose substitution in coffee/tea affect BMI?
Emerging Evidence
Sucralose substitution in coffee/tea appears to affect BMI.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
BMI
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Sucralose substitution in coffee/tea affect body weight?
Emerging Evidence
Sucralose substitution in coffee/tea appears to affect body weight.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Sucralose substitution in coffee/tea improve carbohydrate intake?
Emerging Evidence
Sucralose substitution in coffee/tea appears to improve carbohydrate intake.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Carbohydrate intake
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Sucralose substitution in coffee/tea improve change in visceral adiposity index?
Emerging Evidence
Sucralose substitution in coffee/tea appears to improve change in visceral adiposity index.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Change in Visceral Adiposity Index
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
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