Research Summary
Analyzed using Evidence Intelligence™

Very-low-energy diet may improve Type 2 diabetes remission.

Last updated August 22, 2026

Key finding

Weight fell from 98.0 ± 2.6 to 83.8 ± 2.4 kg.

This study evaluated the feasibility and acceptability of a very-low-energy diet for reversing Type 2 diabetes in motivated participants.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the feasibility and acceptability of a very-low-energy diet for reversing Type 2 diabetes in motivated participants.

Clinical relevance

This study highlights the potential of dietary interventions in managing Type 2 diabetes, particularly for individuals who are motivated to change their lifestyle. The findings suggest that with appropriate support, significant weight loss and improvements in health markers can be achieved, which may lead to better long-term outcomes for diabetes management.

Keep in mind

The sample size was limited to 30 participants. The study only included motivated individuals, which may affect generalizability. Effectiveness of the diet remains unclear due to lack of statistical significance.

Published in

Journal Reference

Publication details and source links for this paper.

L. R, V. A, A. JA, S. S, R. T, F. FS. Dietary treatment for reversal of Type 2 diabetes is acceptable and feasible in motivated participants. Diabetic Medicine. 2017;34(11):1554-1567. doi:10.1111/dme.13426

Main Effects

Participants experienced a weight reduction of 14.2 kg.

12 out of 30 participants achieved fasting plasma glucose levels below 7 mmol/l.

Participants reported improved psychological and physical well-being.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Very-low-energy diet and Acceptability of the very-low-energy diet, Diabetes social support, Fasting Plasma Glucose (FPG), and 2 more.

Primary intervention

Very-low-energy diet

Primary outcomes

  • Acceptability of the very-low-energy diet
  • Diabetes social support
  • Fasting Plasma Glucose (FPG)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

5
Evidence pairs
5
Relationships
4
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

4

Related topics

5

Evidence pairs

1275

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 5 evidence relationships
  • Includes primary outcome data
  • Linked to 4 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

Diabetes Social Support

matched_outcome

Related evidence

Evidence topic

Fasting Blood Glucose

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Acceptability of the very-low-energy diet

Very-low-energy diet → Acceptability of the very-low-energy diet

Very-low-energy diet → Acceptability of the very-low-energy diet

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Diabetes social support

Very-low-energy diet → Diabetes social support

Very-low-energy diet → Diabetes social support

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Very-low-energy diet → Fasting Plasma Glucose (FPG)

Very-low-energy diet → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Improvement in Well-Being

Very-low-energy diet → Improvement in Well-Being

Very-low-energy diet → Improvement in Well-Being

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Weight change

Very-low-energy diet → Weight change

Very-low-energy diet → Weight change

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Weight decreased by an average of 14.2 kg.
  • 12 participants achieved fasting plasma glucose < 7 mmol/l.
  • Participants found adherence to the diet easier than expected.
who this applies

Who this applies to

  • Adults with Type 2 diabetes.
  • Individuals motivated to change their dietary habits.
keep in mind

Keep in Mind

  • Results may not apply to less motivated individuals.
  • The study did not assess long-term sustainability of the diet.
  • Further research is needed to confirm effectiveness across diverse populations.
between the lines

Between the Lines

  • The sample size was limited to 30 participants.
  • The study only included motivated individuals, which may affect generalizability.
  • Effectiveness of the diet remains unclear due to lack of statistical significance.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Very-low-energy diet and Acceptability of the very-low-energy diet, Very-low-energy diet and Social Support in Diabetes.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Very-low-energy diet improve acceptability of the very-low-energy diet?

Emerging Evidence

Very-low-energy diet appears to improve acceptability of the very-low-energy diet.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Acceptability of the very-low-energy diet

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Very-low-energy diet improve fasting plasma glucose (FPG)?

Emerging Evidence

Very-low-energy diet appears to improve fasting plasma glucose (FPG).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

What evidence is available on Very-low-energy diet and improvement in well-being?

Emerging Evidence

Very-low-energy diet appears to improve improvement in well-being.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Improvement in Well-Being

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Very-low-energy diet improve weight change?

Emerging Evidence

Very-low-energy diet appears to improve weight change.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Weight change

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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