Research Summary
Analyzed using Evidence Intelligence™

Aerobic and resistance exercise improve blood glucose control in pre-diabetes

Last updated September 12, 2026

Key finding

FPG decreased by 6.17% (P = 0.001)

This randomized controlled trial examined the effects of aerobic and resistance exercise interventions on pre-diabetes outcomes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This randomized controlled trial examined the effects of aerobic and resistance exercise interventions on pre-diabetes outcomes.

Clinical relevance

With the rising prevalence of pre-diabetes, understanding effective interventions is crucial. This study highlights how structured exercise programs can significantly reduce risk factors associated with diabetes, suggesting that healthcare providers should consider recommending these interventions to at-risk populations.

Keep in mind

The study did not assess long-term effects beyond the intervention period. Sample size and demographic diversity may limit generalizability. Potential confounding factors were not fully controlled.

Published in

Journal Reference

Publication details and source links for this paper.

Xijuan L, Zhengzhen W, Bowen L, Xianbo Z, Xin L. Different impacts of aerobic and resistance exercise intervention on pre-diabetes: a randomized controlled trial. Trials. 2023;24:110. doi:10.1186/s13063-023-07116-3

Main Effects

Fasting plasma glucose decreased by 6.17% (P = 0.001) in the aerobic group.

2-hour glucose following OGTT decreased by 20.39% (P < 0.001) in the resistance group.

HOMA2-IR decreased by 18.31% (P = 0.001) in the resistance exercise group.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Aerobic exercise, Control Group Usual Activity, Taichi plus resistance band training and 2-hour plasma glucose, BMI, Fasting Plasma Glucose (FPG), and 3 more.

Primary intervention

Aerobic exercise

Primary outcomes

  • 2-hour plasma glucose
  • BMI
  • Fasting Plasma Glucose (FPG)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

10
Evidence pairs
10
Relationships
7
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

7

Related topics

10

Evidence pairs

1604

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 10 evidence relationships
  • Includes primary outcome data
  • Linked to 7 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Aerobic Exercise and Body Composition

Related evidence

Evidence relationship

Aerobic Exercise and Fasting Glucose

Save evidence

Evidence relationship

Aerobic Exercise and Postprandial and OGTT Glucose

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

2-hour plasma glucose

Aerobic exercise → 2-hour plasma glucose

Aerobic exercise → 2-hour plasma glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

BMI

Aerobic exercise → BMI

Aerobic exercise → BMI

Evidence Intelligence™
EvidenceScore™
83
Strong
ImpactScore™
92
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 6 studies
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Aerobic exercise → Fasting Plasma Glucose (FPG)

Aerobic exercise → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
83
Strong
ImpactScore™
86
Very Positive
ConsistencyScore™
86
consistent
Supporting studies: Based on 7 studies
Add to Evidence Tracker

HOMA-IR (Supplement)

Aerobic exercise → HOMA-IR (Supplement)

Aerobic exercise → HOMA-IR (Supplement)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Waist circumference

Aerobic exercise → Waist circumference

Aerobic exercise → Waist circumference

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Control Group Usual Activity → Fasting Plasma Glucose (FPG)

Control Group Usual Activity → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 4 studies
ImpactScore™
50
Neutral
ConsistencyScore™
100
consistent
Supporting studies: Based on 4 studies
Add to Evidence Tracker

2-hour plasma glucose

Taichi plus resistance band training → 2-hour plasma glucose

Taichi plus resistance band training → 2-hour plasma glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Taichi plus resistance band training → Fasting Plasma Glucose (FPG)

Taichi plus resistance band training → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 4 studies
ImpactScore™
88
Very Positive
ConsistencyScore™
75
consistent
Supporting studies: Based on 4 studies
Add to Evidence Tracker

Glycated serum protein (GSP) levels

Taichi plus resistance band training → Glycated serum protein (GSP) levels

Taichi plus resistance band training → Glycated serum protein (GSP) levels

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HOMA-IR (Supplement)

Taichi plus resistance band training → HOMA-IR (Supplement)

Taichi plus resistance band training → HOMA-IR (Supplement)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Aerobic exercise led to a significant 6.17% decrease in fasting plasma glucose.
  • Resistance exercise resulted in an 18.31% reduction in insulin resistance (HOMA2-IR).
  • Glycosylated serum protein decreased by 65.2% compared to the control group.
who this applies

Who this applies to

  • Adults diagnosed with pre-diabetes.
  • Individuals at risk for developing type 2 diabetes.
keep in mind

Keep in Mind

  • Results may not apply to populations outside the study's demographic.
  • The study focused on short-term outcomes; long-term effects remain unclear.
  • Exercise adherence and individual variations in response to interventions were not fully explored.
between the lines

Between the Lines

  • The study did not assess long-term effects beyond the intervention period.
  • Sample size and demographic diversity may limit generalizability.
  • Potential confounding factors were not fully controlled.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Aerobic Exercise and Body Mass Index, Aerobic Exercise and Fasting Glucose.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Aerobic Exercise improve body composition?

Strong Evidence

Aerobic Exercise appears to improve body composition.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Waist circumference

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 9 supporting studies with consistent results and a positive effect signal.

9 supporting studies

Does Aerobic Exercise improve fasting glucose?

Strong Evidence

Aerobic Exercise appears to improve fasting glucose.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Strong | EvidenceScore™ 83.2 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 14 supporting studies with consistent results and a positive effect signal.

14 supporting studies

Does Aerobic Exercise improve postprandial and ogtt glucose?

Strong Evidence

Aerobic Exercise may improve postprandial and ogtt glucose.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    2-hour plasma glucose

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 8 supporting studies with generally consistent results and a positive effect signal.

8 supporting studies

Does Aerobic Exercise affect body mass index?

Strong Evidence

Aerobic Exercise appears to affect body mass index.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    BMI

    EvidenceScore™ Strong | EvidenceScore™ 83.4 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 7 supporting studies with consistent results and a positive effect signal.

7 supporting studies
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