July 2026
Added to Dediabetes Jul 12, 2026RCTs
This study compared the effectiveness of Vitadio digital therapy and an intensive in-person weight loss program. Both interventions resulted in significant weight loss and improvements in various health metrics.
Interventions
Vitadio digital therapy
Outcomes
ASTBMIBody fat mass+6 more
Added to Dediabetes Jul 12, 2026RCTs
The J-DOIT3 trial analyzed the effects of intensified multifactorial intervention on glycemic management in type 2 diabetes, finding that intensive therapy reduced the risk of retinopathy onset.
Interventions
Telephone-based lifestyle education for gestational diabetes prevention
Outcomes
Diabetic retinopathy incidenceLoss of vision likely due to retinopathyRetinopathy progression
Added to Dediabetes Jul 12, 2026Pooled IPD Analysis Of Three Randomised Controlled Trials
This study combined data from three European trials of lifestyle programmes for people with prediabetes. The lifestyle programme cut diabetes risk by 57% overall, and those who lost 5% or more of their body weight in the first year had a 65% lower risk. Keeping the weight off for longer led to even greater protection.
Interventions
Lifestyle intervention for prediabetes
Outcomes
Body weightType 2 diabetes incidence
Added to Dediabetes Jul 12, 2026RCTs
This study investigated the effects of interval walking on postprandial glycemic control in individuals with type 2 diabetes, finding significant improvements with one of the walking interventions.
Interventions
Interval walking
Outcomes
Postprandial blood glucose
Added to Dediabetes Jul 12, 2026RCTs
Traditional lifestyle interventions, including low carbohydrate and Mediterranean diets, showed improvements in continuous glucose monitoring metrics within four days.
Interventions
Active dayInterval walkingLow-carbohydrate diet+1 more
Outcomes
Mean amplitude of glycemic excursions (MAGE)Pre-meal mean glucoseTime above range
Added to Dediabetes Jul 12, 2026RCTs
The study evaluated the effect of Finerenone on hypokalaemia in patients with chronic kidney disease and type 2 diabetes, finding a significant reduction in incidence compared to placebo.
Interventions
Finerenone (nonsteroidal mineralocorticoid receptor antagonist)
Outcomes
Arrhythmia composite outcomeComposite cardiovascular events (CV death, MI, stroke, HF hospitalization)Hypokalaemia incidence
Added to Dediabetes Jul 12, 2026RCTs
This study evaluated the addition of glargine, glimepiride, liraglutide, or sitagliptin to metformin in type 2 diabetes. It found varying rates of hypoglycemia among the different treatments.
Interventions
Glargine U100GlimepirideLiraglutide+1 more
Outcomes
Hypoglycemic symptomsSevere hypoglycemia
Added to Dediabetes Jul 12, 2026RCTs
Semaglutide and dulaglutide administered weekly to adults with type 2 diabetes and obesity.
Interventions
DulaglutideMetforminSemaglutide
Outcomes
BMIEpicardial adipose tissue thicknessHbA1c
Added to Dediabetes Jul 12, 2026RCTs
This study investigated the effects of GLP-1 receptor agonists, liraglutide and semaglutide, on cardiovascular outcomes in diabetes, finding significant reductions in major adverse cardiovascular events.
Interventions
LiraglutideSemaglutide
Outcomes
Cardiovascular deathComposite cardiovascular events (CV death, MI, stroke, HF hospitalization)Incidence of myocardial infarction+1 more
Added to Dediabetes Jul 12, 2026Non Randomized CT
This case report examined the effects of high-dose vitamin D therapy on partial clinical remission in a participant with Type 1 Diabetes.
Interventions
Vitamin D supplementation
Outcomes
HbA1cInsulin-dose adjusted A1c (IDAA1c)Serum 25-hydroxyvitamin D+2 more