Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Digital therapy shows comparable effectiveness to in-person weight loss programs
Última actualización 8 de julio de 2026
Key finding
The intervention group experienced an average weight decrease of -7.25 kg (p < 0.001).
This study compared the effectiveness of Vitadio digital therapy and an intensive in-person weight loss program. Both interventions resulted in significant weight loss and improvements in various health metrics.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study compared the effectiveness of Vitadio digital therapy and an intensive in-person weight loss program. Both interventions resulted in significant weight loss and improvements in various health metrics.
Clinical relevance
The findings highlight the potential of digital health interventions like Vitadio to provide effective weight loss solutions, especially for individuals who may have difficulty accessing in-person programs. These results are significant for public health as they suggest that digital therapies can achieve similar health outcomes, making weight loss support more accessible.
Keep in mind
Limited generalizability due to specific participant characteristics Potential for self-reporting bias in weight and health metrics Short duration of follow-up may not capture long-term effects
Published in
Referencia de la Revista
Publication details and source links for this paper.
Katarína M, Markéta S, Jaromír O, et al. Digital Weight Loss Interventions: A Randomized Controlled Non-Inferiority Trial Comparing Vitadio Digital Therapy and In-Person Programs. Nutrients. 2024;16(10):1510. doi:10.3390/nu16101510
Efectos Principales
Average weight loss of -7.25 kg (p < 0.001)
BMI decreased by -2.54 kg/m² (p < 0.001)
Waist circumference reduced by -6.12 cm (p < 0.001)
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Vitadio digital therapy and AST, BMI, Body fat mass, and 6 more.
This study contributes evidence to
Primary intervention
Vitadio digital therapy
Primary outcomes
- AST
- BMI
- Body fat mass
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
9
Evidence pairs
9
Relationships
2
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 64
2
Related topics
9
Evidence pairs
487
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 9 evidence relationships
- Includes primary outcome data
- Linked to 2 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Relación de evidencia
Digital Lifestyle Interventions and Body Weight
Evidencia relacionada
Relación de evidencia
Digital Lifestyle Interventions and Body Mass Index
Guardar evidencia
Relación de evidencia
Digital Lifestyle Interventions and HbA1c
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerChange in liver enzymes (GGT)
Vitadio digital therapy → Change in liver enzymes (GGT)
Vitadio digital therapy → Change in liver enzymes (GGT)
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerTotal cholesterol
Vitadio digital therapy → Total cholesterol
Vitadio digital therapy → Total cholesterol
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerWaist circumference
Vitadio digital therapy → Waist circumference
Vitadio digital therapy → Waist circumference
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
La Evidencia Sugiere
- Weight decreased by an average of -7.25 kg with digital therapy.
- BMI reduced by -2.54 kg/m², indicating significant health improvement.
- Waist circumference decreased by -6.12 cm, reflecting fat loss.
A quién se aplica
- Adults seeking weight loss solutions
- Individuals with limited access to in-person weight loss programs
Tener en Cuenta
- Results may not apply to populations outside the study demographics.
- The study's short duration limits understanding of long-term sustainability.
- Further research is needed to confirm these findings across diverse populations.
Entre Líneas
- Limited generalizability due to specific participant characteristics
- Potential for self-reporting bias in weight and health metrics
- Short duration of follow-up may not capture long-term effects
Evidence Library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Digital Lifestyle Interventions and AST, Digital Lifestyle Interventions and Body Mass Index.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Devices & Technology
Digital Lifestyle Interventions → AST
Devices & Technology
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceDevices & Technology
Digital Lifestyle Interventions → Body Mass Index
Devices & Technology
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceDevices & Technology
Digital Lifestyle Interventions → Adipokine and Angiogenic Markers
Devices & Technology
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Adipokine and Angiogenic Markers Evidence Hub
All studies measuring Adipokine and Angiogenic Markers
1 studies
outcome_hubMeasures Adipokine and Angiogenic Markers as a key outcome.
AST Evidence Hub
All studies measuring AST
1 studies
outcome_hubMeasures AST as a key outcome.
Body Mass Index Evidence Hub
All studies measuring Body Mass Index
1 studies
outcome_hubMeasures Body Mass Index as a key outcome.
Digital Lifestyle Interventions Evidence Hub
All studies on Digital Lifestyle Interventions
1 studies
intervention_hubContributes to Digital Lifestyle Interventions evidence base.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Vitadio digital therapy and AST
Intervention: Vitadio digital therapyOutcome: AST
1 results
All studies on Vitadio digital therapy and BMI
Intervention: Vitadio digital therapyOutcome: BMI
1 results
All studies on Vitadio digital therapy
Intervention: Vitadio digital therapy
1 results
All studies measuring AST
Outcome: AST
1 results
All studies measuring BMI
Outcome: BMI
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Digital Lifestyle Interventions affect body weight?
Strong Evidence
Digital Lifestyle Interventions appears to improve Body Weight.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Weight change
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 4 supporting studies with consistent results and a positive effect signal.
Limitations
- Population details are unavailable.
Does Digital Lifestyle Interventions improve HbA1c?
Strong Evidence
Digital Lifestyle Interventions appears to improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies with consistent results and a positive effect signal.
Limitations
- Population details are unavailable.
Does Digital Lifestyle Interventions affect body mass index?
Strong Evidence
Digital Lifestyle Interventions may improve Body Mass Index.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
BMI
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Limitations
- Population details are unavailable.
Does Digital Lifestyle Interventions improve body composition?
Moderate Evidence
Digital Lifestyle Interventions may improve Body Composition.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
Body fat mass
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
- 2
Waist circumference
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only a small number of supporting studies are available.
- Population details are unavailable.
Next steps
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Evidence topics
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