Evidence Intelligence™
- EvidenceScore™
- 84
- Strong
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 5 estudios
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Intermittent fasting aids weight loss in type 2 diabetes
Última actualización 15 de julio de 2026
Key finding
The IF group exhibited a significant decline in HbA1c levels (p < 0.05).
This study investigated the effects of intermittent fasting on glycaemic control and weight management in insulin-treated type 2 diabetes, finding significant improvements in the fasting group.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of intermittent fasting on glycaemic control and weight management in insulin-treated type 2 diabetes, finding significant improvements in the fasting group.
Clinical relevance
These findings are clinically significant as they suggest that intermittent fasting can be an effective dietary strategy for improving glycaemic control and aiding weight management in patients with insulin-treated type 2 diabetes. This could lead to better overall health outcomes and reduced reliance on insulin therapy for some patients.
Keep in mind
The study's sample size may limit the generalizability of the findings. The duration of the intervention may not reflect long-term effects. Potential confounding factors were not fully controlled.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Kehkishan A, Anna R, Caren S, et al. Intermittent Fasting Improves Glycaemic Control and Weight Management in Insulin-Treated Type 2 Diabetes: A Randomised Controlled Trial. Diabetes, Obesity & Metabolism. 2025;27(3):1605-1608. doi:10.1111/dom.16158
Efectos Principales
The IF group demonstrated a significant decline in HbA1c levels by -2.1 mmol/mol (p < 0.05).
Weight reduction was significantly greater in the IF group, with 4 more participants achieving the composite outcome (p < 0.05).
The control group showed an increase in HbA1c levels by 2.3 mmol/mol (p = 0.317).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Intermittent Fasting (IF) and HbA1c, Total daily insulin dose, Weight change.
This study contributes evidence to
Primary intervention
Intermittent Fasting (IF)
Primary outcomes
- HbA1c
- Total daily insulin dose
- Weight change
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
3
Evidence pairs
3
Relationships
3
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 72
3
Related topics
3
Evidence pairs
1787
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 3 evidence relationships
- Includes primary outcome data
- Linked to 3 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
Dietary Patterns
matched_intervention_and_outcome
Evidencia relacionada
Tema de evidencia
HbA1c Reduction
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Total daily insulin dose
Intermittent Fasting (IF) → Total daily insulin dose
Intermittent Fasting (IF) → Total daily insulin dose
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 3 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 3 estudios
Add to Evidence TrackerEvidence Library
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La Evidencia Sugiere
- Intermittent fasting led to a significant decrease in HbA1c levels by -2.1 mmol/mol.
- Participants in the IF group achieved weight reduction more effectively, with 4 additional participants meeting the composite outcome.
- The control group experienced an increase in daily insulin dose.
A quién se aplica
- Adults with insulin-treated type 2 diabetes.
- Individuals seeking dietary strategies for better glycaemic control.
Tener en Cuenta
- Results may not be applicable to all populations with diabetes.
- Further research is needed to confirm long-term effects of intermittent fasting.
- The study did not explore the psychological effects of fasting on participants.
Entre Líneas
- The study's sample size may limit the generalizability of the findings.
- The duration of the intervention may not reflect long-term effects.
- Potential confounding factors were not fully controlled.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Intermittent Fasting (IF) and HbA1c, Intermittent Fasting (IF) and Body Weight.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Intermittent Fasting (IF) → HbA1c
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- 84
- Strong
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 5 estudios
View evidenceDiet and Nutrition
Intermittent Fasting (IF) → Body Weight
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 3 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 3 estudios
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
HbA1c Evidence Hub
All studies measuring HbA1c
5 studies
outcome_hubMeasures HbA1c as a key outcome.
Intermittent Fasting (IF) Evidence Hub
All studies on Intermittent Fasting (IF)
5 studies
intervention_hubContributes to Intermittent Fasting (IF) evidence base.
Body Weight Evidence Hub
All studies measuring Body Weight
3 studies
outcome_hubMeasures Body Weight as a key outcome.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Intermittent Fasting (IF) and HbA1c
Intervention: Intermittent Fasting (IF)Outcome: HbA1c
5 results
All studies on Intermittent Fasting (IF) and Weight change
Intervention: Intermittent Fasting (IF)Outcome: Weight change
3 results
All studies on Intermittent Fasting (IF)
Intervention: Intermittent Fasting (IF)
5 results
All studies measuring HbA1c
Outcome: HbA1c
5 results
All studies measuring Weight change
Outcome: Weight change
3 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Intermittent Fasting (IF) lower HbA1c?
Strong Evidence
Intermittent Fasting (IF) appears to lower HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 83.8 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Intermittent Fasting (IF) improve weight change?
Strong Evidence
Intermittent Fasting (IF) appears to improve weight change.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Weight change
EvidenceScore™ Strong | EvidenceScore™ 79.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Intermittent Fasting (IF) improve total daily insulin dose?
Moderate Evidence
Intermittent Fasting (IF) may improve total daily insulin dose.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Total daily insulin dose
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Next steps
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Evidence topics
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Related research
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