Última actualización 3 de julio de 2026
Key finding
Vitamin D supplementation could inhibit the decrease in the ankle-brachial index (mean ± SD: EX + VD and VD, -0.001 ± 0.058; p = 0.03).
Moderate and vigorous exercise program with or without vitamin D supplementation in adults with type 2 diabetes.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
Moderate and vigorous exercise program with or without vitamin D supplementation in adults with type 2 diabetes.
This study evaluated Moderate and vigorous exercise program with or without vitamin D supplementation in adults with type 2 diabetes.
Limitations were not clearly described in the extracted text.
Published in
Publication details and source links for this paper.
Jiaju H, Zhongying L, Rui L, et al. Effects of a 12-Week Moderate and Vigorous Exercise Program with or without Vitamin D Supplementation on Arterial Stiffness in Patients with Type 2 Diabetes. Nutrients. 2024;16(21):3618. doi:10.3390/nu16213618
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Vitamin D supplementation and Ankle-brachial index (ABI), Brachial-ankle pulse wave velocity (baPWV), Diastolic blood pressure, and 2 more.
This study contributes evidence to
Primary intervention
Vitamin D supplementation
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
5
Evidence pairs
149
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
matched_outcome
Evidencia relacionada
Tema de evidencia
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Core evidence
The primary outcomes reported in this study.
Vitamin D supplementation → Ankle-brachial index (ABI)
Vitamin D supplementation → Ankle-brachial index (ABI)
Vitamin D supplementation → Brachial-ankle pulse wave velocity (baPWV)
Vitamin D supplementation → Brachial-ankle pulse wave velocity (baPWV)
Vitamin D supplementation → Diastolic blood pressure
Vitamin D supplementation → Diastolic blood pressure
Vitamin D supplementation → Plasma lipidome changes
Vitamin D supplementation → Plasma lipidome changes
Vitamin D supplementation → Systolic blood pressure
Vitamin D supplementation → Systolic blood pressure
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Vitamin D supplementation and Left Ventricular Structure, Vitamin D supplementation and Cardiovascular Outcomes.
This study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Curated evidence collections and hubs this study is part of.
All studies measuring Left Ventricular Structure
Measures Left Ventricular Structure as a key outcome.
All studies on Vitamin D supplementation
Contributes to Vitamin D supplementation evidence base.
All studies measuring Blood Pressure
Measures Blood Pressure as a key outcome.
All studies measuring Cardiovascular Outcomes
Measures Cardiovascular Outcomes as a key outcome.
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Published within the last 2 years.
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2 results
1 results
2 results
2 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Vitamin D supplementation appears to improve Ankle-brachial index (ABI).
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Ankle-brachial index (ABI)
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Vitamin D supplementation appears to improve Plasma lipidome changes.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Plasma lipidome changes
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Vitamin D supplementation for Brachial-ankle pulse wave velocity (baPWV).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Brachial-ankle pulse wave velocity (baPWV)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Vitamin D supplementation for Diastolic blood pressure.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Diastolic blood pressure
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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