Evidence on outcomes studied for Insulin Therapies
Evidence related to insulin therapies in diabetes studies.
Research documents analyzed
Intervention-outcome relationships
Avg. Evidence: 51/100
Qualitative overview of the evidence landscape
Based on 8 studies, moderate evidence suggests Total daily insulin dose, Body Mass Index (BMI) change, Glycemia risk index are the strongest-supported outcomes for insulin therapies.
A structured summary of where the evidence is strongest, mixed, or still emerging.
Use these signals to quickly spot the clearest findings, unsettled areas, and promising gaps.
These entities combine positive direction, stronger evidence, and consistent results.
These entities include mixed, neutral, or conflicting result patterns.
These entities show a positive signal but have limited study volume, RCT depth, or evidence strength.
Total daily insulin dose, Fasting Plasma Glucose (FPG), and Urinary albumin-to-creatinine ratio are among the most studied areas in relation to Insulin Therapies.
Consistency: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Total daily insulin dose
Moderate | score 60.0 | strong positive | Consistent | 2 studies
24-Hour Urinary Protein (24hUpr)
Emerging | score 57.0 | strong positive | Unclear | 1 study
Endothelin-1 (ET-1)
Emerging | score 57.0 | strong positive | Unclear | 1 study
Why this answer: This answer is based on 8 supporting studies and existing graph evidence signals.
Limitations
Insulin Therapies may improve HbA1c.
Consistency: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
HbA1c
Emerging | score 52.3 | weak positive | Generally Consistent | 7 studies
Why this answer: This answer is based on 7 supporting studies and existing graph evidence signals.
Limitations
Total daily insulin dose, Fasting Plasma Glucose (FPG), and Urinary albumin-to-creatinine ratio have the strongest available evidence signals for Insulin Therapies.
Consistency: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Total daily insulin dose
Moderate | score 60.0 | strong positive | Consistent | 2 studies
24-Hour Urinary Protein (24hUpr)
Emerging | score 57.0 | strong positive | Unclear | 1 study
Endothelin-1 (ET-1)
Emerging | score 57.0 | strong positive | Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies and existing graph evidence signals.
Limitations
Total daily insulin dose, Fasting Plasma Glucose (FPG), and Urinary albumin-to-creatinine ratio need more research in relation to Insulin Therapies.
Consistency: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Total daily insulin dose
Moderate | score 60.0 | strong positive | Consistent | 2 studies
24-Hour Urinary Protein (24hUpr)
Emerging | score 57.0 | strong positive | Unclear | 1 study
Endothelin-1 (ET-1)
Emerging | score 57.0 | strong positive | Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies and existing graph evidence signals.
Limitations
Total daily insulin dose, Fasting Plasma Glucose (FPG), and Urinary albumin-to-creatinine ratio have available evidence for Insulin Therapies, but the comparison requires review of the underlying studies.
Consistency: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Total daily insulin dose
Moderate | score 60.0 | strong positive | Consistent | 2 studies
24-Hour Urinary Protein (24hUpr)
Emerging | score 57.0 | strong positive | Unclear | 1 study
Endothelin-1 (ET-1)
Emerging | score 57.0 | strong positive | Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies and existing graph evidence signals.
Limitations
Outcome areas reported in the evidence summary.
Key patterns and insights identified across the research landscape
Across 2 studies, Insulin glargine/lixisenatide fixed-ratio combination (iGlarLixi) shows a consistent strong positive signal for Total daily insulin dose.
Across 1 study, Insulin therapy shows a strong positive signal for 24-Hour Urinary Protein (24hUpr).
Across 1 study, Insulin therapy shows a strong positive signal for Endothelin-1 (ET-1).
Across 1 study, Insulin therapy shows a strong positive signal for Estimated glomerular filtration rate.
Across 1 study, Insulin therapy shows a strong positive signal for Fasting Plasma Glucose (FPG).
Studies connected to this intervention in the evidence record.
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