PrediabetesPreventionBehavioral Intervention
Research Summary
Analyzed using Evidence Intelligence™

Peer-support lifestyle program reduces diabetes risk factors but not diabetes incidence in high-risk Indians

Last updated June 3, 2026

Key finding

A low-cost peer-support lifestyle program improved dietary intake, alcohol use, and physical functioning but did not significantly reduce diabetes incidence at 24 months in high-risk Indians.

This cluster-randomized trial tested a community-based peer-support lifestyle program in 1,007 high-risk Indian adults. The program improved diet, reduced alcohol use, and enhanced physical functioning, but the 14.9% vs 17.1% reduction in diabetes incidence was not statistically significant.

Quick read

Study at a glance

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EvidenceScore™

Moderate

Study type

Randomized Controlled Trials (RCTs)

Follow-up

Long-Term (> 12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

A low-cost peer-support lifestyle program improved dietary intake, alcohol use, and physical functioning but did not significantly reduce diabetes incidence at 24 months in high-risk Indians.

Published in

Journal Reference

Publication details and source links for this paper.

Sathish T, Oldenburg B, et al. A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program. PLoS Med. 2018;15(6):e1002575.

Main Effects

Diabetes incidence: ↓ non-significant (14.9% vs 17.1%, RR 0.88, p=0.36)

IDRS score: ↓ -1.50 points (p=0.022)

Alcohol use: ↓ RR 0.77 (p=0.018)

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Peer-support lifestyle program and Alcohol use, Fruit and vegetable intake, Indian Diabetes Risk Score, and 2 more.

Primary intervention

Peer-support lifestyle program

Primary outcomes

  • Alcohol use
  • Fruit and vegetable intake
  • Indian Diabetes Risk Score

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

5
Evidence pairs
5
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

3

Related topics

5

Evidence pairs

290

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 5 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Diabetes Self-Management Education and Support (DSMES) Programs and Quality of Life Outcomes

Related evidence

Evidence relationship

Diabetes Self-Management Education and Support (DSMES) Programs and Diabetes Incidence and Prevention

Save evidence

Evidence topic

Prediabetes

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Alcohol use

Peer-support lifestyle program → Alcohol use

Peer-support lifestyle program → Alcohol use

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fruit and vegetable intake

Peer-support lifestyle program → Fruit and vegetable intake

Peer-support lifestyle program → Fruit and vegetable intake

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Indian Diabetes Risk Score

Peer-support lifestyle program → Indian Diabetes Risk Score

Peer-support lifestyle program → Indian Diabetes Risk Score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Quality of life

Peer-support lifestyle program → Quality of life

Peer-support lifestyle program → Quality of life

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Type 2 diabetes incidence

Peer-support lifestyle program → Type 2 diabetes incidence

Peer-support lifestyle program → Type 2 diabetes incidence

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
55
Slightly Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Peer-support lifestyle program improved diet quality and physical functioning at 24 months
  • Alcohol use was significantly reduced in the intervention group
  • Diabetes incidence was lower but the reduction was not statistically significant
who this applies

Who this applies to

Adults aged 30-60 years with elevated diabetes risk (IDRS ≥60) in LMIC settings

keep in mind

Keep in Mind

The primary outcome (diabetes incidence) did not reach statistical significance

between the lines

Between the Lines

  • Diabetes incidence reduction was not statistically significant
  • No adjustment for multiple comparisons (increases type I error risk)
  • 24-month follow-up may be insufficient to detect diabetes prevention effects

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Diabetes Self-Management Education and Support (DSMES) Programs improve quality of life outcomes?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs appears to improve Quality of Life Outcomes.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    Quality of life

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 10 supporting studies with generally consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
10 supporting studiesUpdated: Jul 2026

Does Diabetes Self-Management Education and Support (DSMES) Programs improve diabetes incidence and prevention?

Moderate Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve Diabetes Incidence and Prevention.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Type 2 diabetes incidence

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | weak positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a small number of supporting studies and should be interpreted cautiously.

Limitations

  • Only a small number of supporting studies are available.
  • Population details are unavailable.
2 supporting studiesUpdated: Jul 2026

Does Peer-support lifestyle program improve alcohol use?

Emerging Evidence

Peer-support lifestyle program appears to improve Alcohol use.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Alcohol use

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Peer-support lifestyle program improve fruit and vegetable intake?

Emerging Evidence

Peer-support lifestyle program appears to improve Fruit and vegetable intake.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fruit and vegetable intake

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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