Healthcare Delivery & EducationType 2 Diabetes (T2D)Complications
Research Summary
Analyzed using Evidence Intelligence™

Team-based diabetes care may improve blood sugar, blood pressure, and albuminuria

Last updated May 29, 2026

Key finding

In 355 people with type 2 diabetes and early diabetic kidney disease, a multidisciplinary care program was linked with improved HbA1c, blood pressure, lipids, and albuminuria.

This Taiwan study reviewed outcomes after people with type 2 diabetes and early diabetic kidney disease joined an integrated care program. The program included education, exercise support, diet counseling, multimedia tools, and team follow-up. Several markers improved from baseline, but the study had no concurrent comparison group.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Low

Study type

non-randomized clinical trial (non-RCT or NRCT)

Follow-up

Medium-Term (3–12 mo)

Risk of bias

High Risk

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

In 355 people with type 2 diabetes and early diabetic kidney disease, a multidisciplinary care program was linked with improved HbA1c, blood pressure, lipids, and albuminuria.

Published in

Journal Reference

Publication details and source links for this paper.

Lo WC, Huang YJ, Tasi YL, Chen JF, Mai HC, Hung YL, Chio YH, Chen CY, Ou YL, Chen SC. Analysis of the association of multidisciplinary team care and education intervention in patients with early-stage diabetic kidney disease in Taiwan. Endocr J. 2026;73(4):517-527. doi:10.1507/endocrj.ej25-0418

Main Effects

↓ HbA1c decreased from 7.51% to 7.10%

↓ Systolic and diastolic blood pressure decreased from baseline

↓ Total cholesterol, LDL cholesterol, and albuminuria decreased

evidence suggest

Evidence Suggest

  • A coordinated multidisciplinary care program may support better glycemic and cardiometabolic risk marker control in early DKD
  • Albuminuria improved, but eGFR declined modestly during follow-up and needs cautious interpretation
  • Medication changes occurred during the program, so non-drug education effects cannot be separated from treatment intensification
who this applies

Who this applies to

Adults with type 2 diabetes and early-stage diabetic kidney disease

keep in mind

Keep in Mind

The study shows before-and-after changes, not definitive cause-and-effect evidence

between the lines

Between the Lines

  • Retrospective design with no concurrent comparison group
  • Single-hospital setting limits generalizability
  • The packaged intervention prevents attribution to any one component
  • Long-term kidney failure or cardiovascular outcomes were not evaluated

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