Research Summary
Analyzed using Evidence Intelligence™

Additional toothbrushing improves oral health in type 2 diabetes patients

Last updated July 22, 2026

Key finding

HbA1c decreased by 0.17 ± 0.27% (p=0.009)

This study evaluated the impact of additional toothbrushing during non-surgical periodontal treatment on oral and general health in patients with type 2 diabetes, finding significant reductions in HbA1c levels.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the impact of additional toothbrushing during non-surgical periodontal treatment on oral and general health in patients with type 2 diabetes, finding significant reductions in HbA1c levels.

Clinical relevance

This study highlights the importance of oral hygiene practices, such as toothbrushing, in managing diabetes and periodontal health. Improved HbA1c levels can lead to better overall health outcomes for patients with type 2 diabetes, emphasizing the need for integrated dental care in diabetes management.

Keep in mind

The study had a limited sample size, which may affect the generalizability of the findings. Long-term effects of the interventions were not assessed. The effectiveness of additional toothbrushing may vary among individuals.

Published in

Journal Reference

Publication details and source links for this paper.

Jae YL, Yoon YC, Youngnim C, Bo HJ. The clinical benefit of additional toothbrushing accompanying non-surgical periodontal treatment on oral and general health in patients with type 2 diabetes mellitus. Journal of Periodontal & Implant Science. 2020;50(2):83-96. doi:10.5051/jpis.2020.50.2.83

Main Effects

HbA1c decreased by 0.25 ± 0.25% (p=0.001) with SRPAT.

Periodontal pocket depth decreased by 0.09 ± 0.18 mm (p=0.039) with SRPAT.

Calculus index decreased by 1.55 ± 1.70 (p=0.001) with SRPAT.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to SRP + OHI, Scaling and root planing with additional toothbrushing (SRPAT) and Bleeding on probing, Calculus Index Decrease, HbA1c, and 3 more.

Primary intervention

SRP + OHI

Primary outcomes

  • Bleeding on probing
  • Calculus Index Decrease
  • HbA1c

Evidence topics

Primary intervention

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

12
Evidence pairs
12
Relationships
1
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 59

1

Related topics

12

Evidence pairs

310

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 12 evidence relationships
  • Includes primary outcome data
  • Linked to 1 direct semantic evidence topic

Topic contributions

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence topic

HbA1c Reduction

matched_outcome

Core evidence

Study findings

The primary outcomes reported in this study.

Bleeding on probing

Scaling and root planing with additional toothbrushing (SRPAT) → Bleeding on probing

Scaling and root planing with additional toothbrushing (SRPAT) → Bleeding on probing

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Calculus Index Decrease

Scaling and root planing with additional toothbrushing (SRPAT) → Calculus Index Decrease

Scaling and root planing with additional toothbrushing (SRPAT) → Calculus Index Decrease

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Scaling and root planing with additional toothbrushing (SRPAT) → HbA1c

Scaling and root planing with additional toothbrushing (SRPAT) → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Interleukin-1 beta levels change

Scaling and root planing with additional toothbrushing (SRPAT) → Interleukin-1 beta levels change

Scaling and root planing with additional toothbrushing (SRPAT) → Interleukin-1 beta levels change

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Periodontal probing depth

Scaling and root planing with additional toothbrushing (SRPAT) → Periodontal probing depth

Scaling and root planing with additional toothbrushing (SRPAT) → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Serum endotoxin levels

Scaling and root planing with additional toothbrushing (SRPAT) → Serum endotoxin levels

Scaling and root planing with additional toothbrushing (SRPAT) → Serum endotoxin levels

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Bleeding on probing

SRP + OHI → Bleeding on probing

SRP + OHI → Bleeding on probing

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 4 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 4 studies
Add to Evidence Tracker

Calculus Index Decrease

SRP + OHI → Calculus Index Decrease

SRP + OHI → Calculus Index Decrease

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

SRP + OHI → HbA1c

SRP + OHI → HbA1c

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 4 studies
ImpactScore™
63
Slightly Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 4 studies
Add to Evidence Tracker

Interleukin-1 beta levels change

SRP + OHI → Interleukin-1 beta levels change

SRP + OHI → Interleukin-1 beta levels change

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Periodontal probing depth

SRP + OHI → Periodontal probing depth

SRP + OHI → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
83
Strong
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 7 studies
Add to Evidence Tracker

Serum endotoxin levels

SRP + OHI → Serum endotoxin levels

SRP + OHI → Serum endotoxin levels

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

Build your evidence library

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evidence suggest

Evidence Suggest

  • HbA1c levels decreased significantly with additional toothbrushing (0.25%).
  • Periodontal pocket depth improved by 0.09 mm with SRPAT.
  • Calculus index showed a significant reduction of 1.55.
who this applies

Who this applies to

  • Adults diagnosed with type 2 diabetes mellitus.
  • Patients undergoing non-surgical periodontal treatment.
keep in mind

Keep in Mind

  • Results may not be applicable to populations outside of the study sample.
  • The study focused on short-term outcomes; long-term benefits remain unclear.
  • Individual responses to treatment may differ based on personal health factors.
between the lines

Between the Lines

  • The study had a limited sample size, which may affect the generalizability of the findings.
  • Long-term effects of the interventions were not assessed.
  • The effectiveness of additional toothbrushing may vary among individuals.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on SRP + OHI and Periodontal probing depth, SRP + OHI and Bleeding on probing.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does SRP + OHI improve periodontal probing depth?

Strong Evidence

SRP + OHI appears to improve Periodontal probing depth.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Periodontal probing depth

    EvidenceScore™ Strong | EvidenceScore™ 83.5 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does SRP + OHI improve bleeding on probing?

Strong Evidence

SRP + OHI appears to improve Bleeding on probing.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Bleeding on probing

    EvidenceScore™ Strong | EvidenceScore™ 79.0 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does SRP + OHI improve HbA1c?

Strong Evidence

SRP + OHI may improve HbA1c.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does SRP + OHI improve calculus index decrease?

Emerging Evidence

SRP + OHI appears to improve Calculus Index Decrease.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Calculus Index Decrease

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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