Research Summary
Analyzed using Evidence Intelligence™

Scaling and root planing improves glycemic control in T2DM

Last updated July 22, 2026

Key finding

HbA1c decreased significantly from baseline.

This study evaluated the impact of scaling and root planing on glycemic control in type 2 diabetes patients, finding significant improvements in various health markers.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the impact of scaling and root planing on glycemic control in type 2 diabetes patients, finding significant improvements in various health markers.

Clinical relevance

Improving glycemic control is crucial for managing type 2 diabetes and preventing complications. This study highlights the potential role of dental interventions, such as scaling and root planing, in enhancing overall health outcomes for diabetic patients. By addressing oral health, clinicians may offer a comprehensive approach to diabetes management.

Keep in mind

Unclear effectiveness for some interventions Limited generalizability due to specific population Potential confounding factors not controlled

Published in

Journal Reference

Publication details and source links for this paper.

Ambrina Q, Syed AHB, Zeba H, Akhtar AB, Sidra Z. Scaling and root planing improves glycemic control in type 2 diabetes patients: a randomized controlled trial. BMC Oral Health. 2021;21:253. doi:10.1186/s12903-021-01620-1

Main Effects

HbA1c decreased by 1.22% (p=0.001)

FBG decreased by 33.32 mg/dL (p=0.023)

BOP decreased significantly from baseline

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Oral hygiene instructions only, Scaling and root planing and oral hygiene instructions, Scaling and root planing with metronidazole and oral hygiene instructions and Bleeding on probing, Clinical attachment level, Fasting blood sugar (FBS), and 2 more.

Primary intervention

Oral hygiene instructions only

Primary outcomes

  • Bleeding on probing
  • Clinical attachment level
  • Fasting blood sugar (FBS)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

15
Evidence pairs
15
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

2

Related topics

15

Evidence pairs

555

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 15 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence topic

Glycemic Control

matched_outcome

Related evidence

Evidence topic

HbA1c Reduction

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Bleeding on probing

Oral hygiene instructions only → Bleeding on probing

Oral hygiene instructions only → Bleeding on probing

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Clinical attachment level

Oral hygiene instructions only → Clinical attachment level

Oral hygiene instructions only → Clinical attachment level

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting blood sugar (FBS)

Oral hygiene instructions only → Fasting blood sugar (FBS)

Oral hygiene instructions only → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Oral hygiene instructions only → HbA1c

Oral hygiene instructions only → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Periodontal probing depth

Oral hygiene instructions only → Periodontal probing depth

Oral hygiene instructions only → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Bleeding on probing

Scaling and root planing and oral hygiene instructions → Bleeding on probing

Scaling and root planing and oral hygiene instructions → Bleeding on probing

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Clinical attachment level

Scaling and root planing and oral hygiene instructions → Clinical attachment level

Scaling and root planing and oral hygiene instructions → Clinical attachment level

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting blood sugar (FBS)

Scaling and root planing and oral hygiene instructions → Fasting blood sugar (FBS)

Scaling and root planing and oral hygiene instructions → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Scaling and root planing and oral hygiene instructions → HbA1c

Scaling and root planing and oral hygiene instructions → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Periodontal probing depth

Scaling and root planing and oral hygiene instructions → Periodontal probing depth

Scaling and root planing and oral hygiene instructions → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Bleeding on probing

Scaling and root planing with metronidazole and oral hygiene instructions → Bleeding on probing

Scaling and root planing with metronidazole and oral hygiene instructions → Bleeding on probing

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Clinical attachment level

Scaling and root planing with metronidazole and oral hygiene instructions → Clinical attachment level

Scaling and root planing with metronidazole and oral hygiene instructions → Clinical attachment level

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting blood sugar (FBS)

Scaling and root planing with metronidazole and oral hygiene instructions → Fasting blood sugar (FBS)

Scaling and root planing with metronidazole and oral hygiene instructions → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Scaling and root planing with metronidazole and oral hygiene instructions → HbA1c

Scaling and root planing with metronidazole and oral hygiene instructions → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Periodontal probing depth

Scaling and root planing with metronidazole and oral hygiene instructions → Periodontal probing depth

Scaling and root planing with metronidazole and oral hygiene instructions → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

Build your evidence library

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evidence suggest

Evidence Suggest

  • HbA1c decreased significantly, indicating improved glycemic control.
  • FBG levels showed a significant reduction, supporting diabetes management.
  • Periodontal health improved, as evidenced by decreased BOP and CAL.
who this applies

Who this applies to

  • Adults diagnosed with type 2 diabetes
  • Patients experiencing periodontal issues
keep in mind

Keep in Mind

  • Results may not apply to all diabetes patients, especially those with different health conditions.
  • Further research is needed to confirm long-term effects.
  • The study focused on a specific population, limiting broader applicability.
between the lines

Between the Lines

  • Unclear effectiveness for some interventions
  • Limited generalizability due to specific population
  • Potential confounding factors not controlled

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Oral hygiene instructions only and Bleeding on probing, Oral hygiene instructions only and Clinical attachment level.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Scaling and root planing and oral hygiene instructions improve bleeding on probing?

Emerging Evidence

Scaling and root planing and oral hygiene instructions appears to improve Bleeding on probing.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Bleeding on probing

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Scaling and root planing and oral hygiene instructions improve clinical attachment level?

Emerging Evidence

Scaling and root planing and oral hygiene instructions appears to improve Clinical attachment level.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Clinical attachment level

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Scaling and root planing and oral hygiene instructions improve fasting blood sugar (fbs)?

Emerging Evidence

Scaling and root planing and oral hygiene instructions appears to improve Fasting blood sugar (FBS).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting blood sugar (FBS)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Scaling and root planing and oral hygiene instructions improve HbA1c?

Emerging Evidence

Scaling and root planing and oral hygiene instructions appears to improve HbA1c.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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