Research Summary
Analyzed using Evidence Intelligence™

Combined diet and exercise intervention improves diabetes markers in adults.

Last updated August 29, 2026

Key finding

FBG levels in the D and D + E groups exhibited a significant reduction (D: ΔFBG = -0.3 ± 1.0 mmol/L; D + E: ΔFBG = -0.3 ± 1.0 mmol/L; both p < 0.05).

Combined diet and exercise intervention in adults with prediabetes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

Combined diet and exercise intervention in adults with prediabetes.

Clinical relevance

This study evaluated Combined diet and exercise intervention in adults with prediabetes.

Keep in mind

Limitations were not clearly described in the extracted text.

Published in

Journal Reference

Publication details and source links for this paper.

Ting Z, Da P, Lanlan G, et al. Metabolomic Biomarkers for Diabetes Progression and Lifestyle Intervention Response. Life. 2026;16(2):198. doi:10.3390/life16020198

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Lifestyle intervention for prediabetes and BMI, Diastolic blood pressure, Fasting Plasma Glucose (FPG), and 4 more.

Primary intervention

Lifestyle intervention for prediabetes

Primary outcomes

  • BMI
  • Diastolic blood pressure
  • Fasting Plasma Glucose (FPG)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
8
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

8

Related topics

7

Evidence pairs

2580

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 8 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

Prediabetes

matched_intervention_and_outcome

Related evidence

Evidence topic

Blood Pressure

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

BMI

Lifestyle intervention for prediabetes → BMI

Lifestyle intervention for prediabetes → BMI

Evidence Intelligence™
EvidenceScore™
87
Strong
ImpactScore™
67
Slightly Positive
ConsistencyScore™
56
generally_consistent
Supporting studies: Based on 9 studies
Add to Evidence Tracker

Diastolic blood pressure

Lifestyle intervention for prediabetes → Diastolic blood pressure

Lifestyle intervention for prediabetes → Diastolic blood pressure

Evidence Intelligence™
EvidenceScore™
83
Strong
ImpactScore™
69
Positive
ConsistencyScore™
60
generally_consistent
Supporting studies: Based on 5 studies
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Lifestyle intervention for prediabetes → Fasting Plasma Glucose (FPG)

Lifestyle intervention for prediabetes → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
87
Strong
ImpactScore™
69
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 9 studies
Add to Evidence Tracker

HbA1c

Lifestyle intervention for prediabetes → HbA1c

Lifestyle intervention for prediabetes → HbA1c

Evidence Intelligence™
EvidenceScore™
87
Strong
ImpactScore™
85
Very Positive
ConsistencyScore™
82
consistent
Supporting studies: Based on 17 studies
Add to Evidence Tracker

Systolic blood pressure

Lifestyle intervention for prediabetes → Systolic blood pressure

Lifestyle intervention for prediabetes → Systolic blood pressure

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 4 studies
ImpactScore™
63
Slightly Positive
ConsistencyScore™
75
consistent
Supporting studies: Based on 4 studies
Add to Evidence Tracker

Type 2 diabetes incidence

Lifestyle intervention for prediabetes → Type 2 diabetes incidence

Lifestyle intervention for prediabetes → Type 2 diabetes incidence

Evidence Intelligence™
EvidenceScore™
88
Strong
ImpactScore™
69
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 8 studies
Add to Evidence Tracker

Waist circumference

Lifestyle intervention for prediabetes → Waist circumference

Lifestyle intervention for prediabetes → Waist circumference

Evidence Intelligence™
EvidenceScore™
83
Strong
ImpactScore™
67
Slightly Positive
ConsistencyScore™
56
generally_consistent
Supporting studies: Based on 9 studies
Add to Evidence Tracker

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Lifestyle intervention for prediabetes and Diabetes Incidence and Prevention, Lifestyle intervention for prediabetes and HbA1c.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Lifestyle intervention for prediabetes reduce type 2 diabetes incidence?

Strong Evidence

Lifestyle intervention for prediabetes may reduce type 2 diabetes incidence.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Type 2 diabetes incidence

    EvidenceScore™ Strong | EvidenceScore™ 87.9 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Lifestyle intervention for prediabetes lower HbA1c?

Strong Evidence

Lifestyle intervention for prediabetes appears to lower HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 87.4 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Lifestyle intervention for prediabetes improve fasting plasma glucose (FPG)?

Strong Evidence

Lifestyle intervention for prediabetes may improve fasting plasma glucose (FPG).

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Strong | EvidenceScore™ 87.1 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Lifestyle intervention for prediabetes affect BMI?

Strong Evidence

Lifestyle intervention for prediabetes may affect BMI.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    BMI

    EvidenceScore™ Strong | EvidenceScore™ 86.7 | weak positive | ConsistencyScore™ Generally Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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