Last updated August 16, 2026
Key finding
WHO-5: mean difference 7.35 (95% confidence interval (CI) 3.15–11.55), P = 0.0007
This study evaluated the impact of a behavioral intervention on psychological well-being and quality of life in individuals with Type 2 diabetes, finding significant improvements in the intervention group.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the impact of a behavioral intervention on psychological well-being and quality of life in individuals with Type 2 diabetes, finding significant improvements in the intervention group.
These findings highlight the importance of behavioral interventions in managing Type 2 diabetes, as they can enhance patients' psychological well-being and overall quality of life. This approach may lead to better health outcomes and a more active lifestyle, which are crucial for diabetes management.
Unclear effectiveness for some outcomes. Limited generalizability due to specific population characteristics. Potential for unmeasured confounders affecting results.
Published in
Publication details and source links for this paper.
Antonio N, Jonida H, Valeria D, et al. Effect of a Behavioural Intervention on Psychological Well-Being and Quality of Life in Individuals with Type 2 Diabetes. Sports Medicine (Auckland, N.z.). 2021;52(3):643-654. doi:10.1007/s40279-021-01556-0
WHO-5 scores increased by 7.35 points (p=0.0007) in the intervention group.
SF-36 physical and mental component scores increased by 4.2 points (p=0.0001) in the intervention group.
The percentage of participants with likely depression decreased by 0.14% in the intervention group.
Evidence network
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This study contributes evidence to Lifestyle intervention for prediabetes and Health-related quality of life, Improvement in Well-Being, Percentage of participants with likely depression, and 1 more.
This study contributes evidence to
Primary intervention
Lifestyle intervention for prediabetes
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
3
Related topics
4
Evidence pairs
259
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_intervention_and_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
Lifestyle intervention for prediabetes → Health-related quality of life
Lifestyle intervention for prediabetes → Health-related quality of life
Lifestyle intervention for prediabetes → Improvement in Well-Being
Lifestyle intervention for prediabetes → Improvement in Well-Being
Lifestyle intervention for prediabetes → Percentage of participants with likely depression
Lifestyle intervention for prediabetes → Percentage of participants with likely depression
Lifestyle intervention for prediabetes → Physical activity level (MET-minutes per week)
Lifestyle intervention for prediabetes → Physical activity level (MET-minutes per week)
Evidence Library
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Lifestyle intervention for prediabetes and Physical Activity Levels, Lifestyle intervention for prediabetes and Quality of Life Outcomes.
This study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Behavioral & Lifestyle
Curated evidence collections and hubs this study is part of.
All studies on Lifestyle intervention for prediabetes
Contributes to Lifestyle intervention for prediabetes evidence base.
All studies measuring Physical Activity Levels
Measures Physical Activity Levels as a key outcome.
All studies measuring Quality of Life Outcomes
Measures Quality of Life Outcomes as a key outcome.
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3 results
1 results
3 results
3 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Lifestyle intervention for prediabetes appears to improve Physical activity level (MET-minutes per week).
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Physical activity level (MET-minutes per week)
EvidenceScore™ Moderate | EvidenceScore™ 72.9 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Lifestyle intervention for prediabetes appears to improve Health-related quality of life.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Health-related quality of life
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Lifestyle intervention for prediabetes appears to improve Improvement in Well-Being.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Improvement in Well-Being
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Lifestyle intervention for prediabetes appears to improve Percentage of participants with likely depression.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Percentage of participants with likely depression
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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