Last updated August 16, 2026
Key finding
Awake systolic blood pressure decreased from 144 to 136 mm Hg (P = 0.004).
This study evaluated the effects of Continuous Positive Airway Pressure (CPAP) on blood pressure in patients with diabetes, chronic kidney disease, and resistant hypertension, finding significant reductions in both awake and sleep blood pressure.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
Save research, organize studies, and quickly find important evidence again.
Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the effects of Continuous Positive Airway Pressure (CPAP) on blood pressure in patients with diabetes, chronic kidney disease, and resistant hypertension, finding significant reductions in both awake and sleep blood pressure.
These findings are clinically significant as they suggest that CPAP therapy could be an effective intervention for managing high blood pressure in patients with diabetes and chronic kidney disease, potentially reducing cardiovascular risks associated with resistant hypertension. This could lead to improved patient outcomes and inform treatment strategies in similar populations.
Limited generalizability due to specific population characteristics. Potential confounding factors not measured. Short duration of follow-up may limit long-term applicability.
Published in
Publication details and source links for this paper.
Marcel R, Greg K, Frans HL, Judith L, Shawn DA, Swapnil H. Effects of Continuous Positive Airway Pressure on Blood Pressure in Patients with Diabetes, Chronic Kidney Disease, and Resistant Hypertension. CJC Open. 2020;2(4):258-264. doi:10.1016/j.cjco.2020.03.010
Awake systolic blood pressure decreased from 144 to 136 mm Hg (P = 0.004).
Awake diastolic blood pressure decreased from 79 to 74 mm Hg (P = 0.004).
Sleep systolic blood pressure decreased from 135 to 119 mm Hg (P = 0.045).
Sleep diastolic blood pressure decreased from 75 to 65 mm Hg (P = 0.015).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Continuous Positive Airway Pressure (CPAP) and Diastolic blood pressure, Muscle sympathetic nerve activity, Systolic blood pressure.
This study contributes evidence to
Primary intervention
Continuous Positive Airway Pressure (CPAP)
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
1
Related topics
3
Evidence pairs
122
Related studies
Evidence topic
Contributes evidence
Save studies and evidence pages, organize your personal Evidence Tracker, and keep the research you care about in one place.
Primary evidence
Evidence topic
matched_outcome
Core evidence
The primary outcomes reported in this study.
Continuous Positive Airway Pressure (CPAP) → Diastolic blood pressure
Continuous Positive Airway Pressure (CPAP) → Diastolic blood pressure
Continuous Positive Airway Pressure (CPAP) → Muscle sympathetic nerve activity
Continuous Positive Airway Pressure (CPAP) → Muscle sympathetic nerve activity
Continuous Positive Airway Pressure (CPAP) → Systolic blood pressure
Continuous Positive Airway Pressure (CPAP) → Systolic blood pressure
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Continuous Positive Airway Pressure (CPAP) and Blood Pressure, Continuous Positive Airway Pressure (CPAP) and Muscle sympathetic nerve activity.
This study contributes to the evidence on the following intervention-outcome relationships.
Devices & Technology
Devices & Technology
Curated evidence collections and hubs this study is part of.
All studies measuring Blood Pressure
Measures Blood Pressure as a key outcome.
All studies on Continuous Positive Airway Pressure (CPAP)
Contributes to Continuous Positive Airway Pressure (CPAP) evidence base.
All studies measuring Muscle sympathetic nerve activity
Measures Muscle sympathetic nerve activity as a key outcome.
Jump to pre-filtered views in Evidence Explorer.
1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Continuous Positive Airway Pressure (CPAP) appears to improve diastolic blood pressure.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Diastolic blood pressure
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Continuous Positive Airway Pressure (CPAP) appears to improve systolic blood pressure.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Systolic blood pressure
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Continuous Positive Airway Pressure (CPAP) for muscle sympathetic nerve activity.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Muscle sympathetic nerve activity
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Next steps
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Open broader Evidence Explorer views for this relationship.
Read related research summaries.
Focused on evidence, not advertising.
Your data is always protected.
New studies added every day.
