StrongDecrease
HbA1c
Date Seed Powder (DSP) → HbA1c
Date Seed Powder (DSP) → HbA1c
Evidence profile
StrongDecreaseGlycemic Control
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Research Summary
Analyzed using Evidence Intelligence™
Date seed powder improves diabetes management
Key finding
HbA1c decreased by -0.30 ± 0.48% (p < 0.05)
The study evaluated the effects of date seed powder supplementation on glycemic control and oxidative stress in type 2 diabetes patients, finding significant improvements in various metabolic markers.
Evidence strength
Moderate confidence
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Some Concerns bias
Last updated July 6, 2026Quick read
Study at a glance
The essential study design details in one scan.
Population
Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes
Intervention
Date Seed Powder (DSP), Placebo (Maltodextrin)
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Primary outcome
HbA1c
Comparator
Placebo Group
Plain-language summary
What this paper says
A plain-language read of the study's main message and where it applies.
Study focus
The study evaluated the effects of date seed powder supplementation on glycemic control and oxidative stress in type 2 diabetes patients, finding significant improvements in various metabolic markers.
Clinical relevance
These findings suggest that date seed powder could be a beneficial dietary supplement for managing type 2 diabetes, potentially leading to better blood sugar control and reduced oxidative stress. This could help improve the quality of life for patients and reduce the risk of diabetes-related complications.
Keep in mind
Limited sample size may affect generalizability. Short duration of the study may not capture long-term effects. Lack of diverse population limits applicability to broader groups.
Published in
Journal Reference
Publication details and source links for this paper.
Mehdi M, Parvin D, Fatemeh A, Parham M. Supplementation of date seed powder improves glycemic control and oxidative stress in type 2 diabetes patients. Nutrition & Diabetes. 2024;14:37. doi:10.1038/s41387-024-00287-1
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Main Effects
HbA1c decreased by -0.30 ± 0.48% (p < 0.05)
Insulin decreased by -1.70 ± 2.21 µU/ml (p < 0.05)
Total Antioxidant Capacity (TAC) increased by 0.50 ± 0.26 mmol/L (p < 0.05)
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Date Seed Powder (DSP) and HOMA-B, HbA1c, Insulin, and 6 more.
This study contributes evidence to
Primary intervention
Date Seed Powder (DSP)
Primary outcomes
- HOMA-B
- HbA1c
- Insulin
Evidence topics
Primary intervention
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
9
Evidence pairs
9
Relationships
1
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 59
1
Related topics
9
Evidence pairs
161
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 9 evidence relationships
- Includes primary outcome data
- Linked to 1 direct semantic evidence topic
Topic contributions
Evidence topic
Contributes evidence
Core evidence
Study findings
The primary outcomes reported in this study.
StrongDecrease
HOMA-B
Date Seed Powder (DSP) → HOMA-B
Date Seed Powder (DSP) → HOMA-B
Evidence profile
StrongDecreaseClinical Outcomes
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StrongDecrease
Insulin
Date Seed Powder (DSP) → Insulin
Date Seed Powder (DSP) → Insulin
Evidence profile
StrongDecreaseGlycemic Control
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StrongDecrease
Insulin resistance
Date Seed Powder (DSP) → Insulin resistance
Date Seed Powder (DSP) → Insulin resistance
Evidence profile
StrongDecreaseMetabolic Health
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StrongDecrease
Lipopolysaccharide (LPS)
Date Seed Powder (DSP) → Lipopolysaccharide (LPS)
Date Seed Powder (DSP) → Lipopolysaccharide (LPS)
Evidence profile
StrongDecreaseClinical Outcomes
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StrongDecrease
Pentosidine
Date Seed Powder (DSP) → Pentosidine
Date Seed Powder (DSP) → Pentosidine
Evidence profile
StrongDecreaseClinical Outcomes
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StrongIncrease
s-RAGE
Date Seed Powder (DSP) → s-RAGE
Date Seed Powder (DSP) → s-RAGE
Evidence profile
StrongIncreaseMetabolic Health
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StrongIncrease
Superoxide Dismutase (SOD)
Date Seed Powder (DSP) → Superoxide Dismutase (SOD)
Date Seed Powder (DSP) → Superoxide Dismutase (SOD)
Evidence profile
StrongIncreaseMetabolic Health
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StrongIncrease
Total Antioxidant Capacity (TAC)
Date Seed Powder (DSP) → Total Antioxidant Capacity (TAC)
Date Seed Powder (DSP) → Total Antioxidant Capacity (TAC)
Evidence profile
StrongIncreaseMetabolic Health
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Create a free account to access effectiveness ratings, evidence strength and depth scores, consistency analysis, and direct links to all supporting studies.
Evidence Suggest
- HbA1c levels decreased significantly by 0.30%.
- Insulin levels reduced by 1.70 µU/ml.
- Total Antioxidant Capacity increased by 0.50 mmol/L.
Who this applies to
- Adults diagnosed with type 2 diabetes.
- Individuals seeking dietary interventions for glycemic control.
Keep in Mind
- Results may not apply to non-diabetic individuals.
- Further research is needed to confirm long-term benefits.
- Effects may vary based on individual dietary habits and lifestyle.
Between the Lines
- Limited sample size may affect generalizability.
- Short duration of the study may not capture long-term effects.
- Lack of diverse population limits applicability to broader groups.
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Date Seed Powder (DSP) and HbA1c, Date Seed Powder (DSP) and HOMA-B.
Related evidence relationships
Explore in Evidence ArchiveThis study contributes to the evidence on the following intervention-outcome relationships.
Included in these evidence collections
Curated evidence collections and hubs this study is part of.
Date Seed Powder (DSP) Evidence Hub
All studies on Date Seed Powder (DSP)
1 studies
intervention_hubContributes to Date Seed Powder (DSP) evidence base.
HbA1c Evidence Hub
All studies measuring HbA1c
1 studies
outcome_hubMeasures HbA1c as a key outcome.
HOMA-B Evidence Hub
All studies measuring HOMA-B
1 studies
outcome_hubMeasures HOMA-B as a key outcome.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in the evidence archive
Jump to pre-filtered views in the evidence archive.
All studies on Date Seed Powder (DSP) and HbA1c
Intervention: Date Seed Powder (DSP)Outcome: HbA1c
1 results
All studies on Date Seed Powder (DSP) and HOMA-B
Intervention: Date Seed Powder (DSP)Outcome: HOMA-B
1 results
All studies on Date Seed Powder (DSP)
Intervention: Date Seed Powder (DSP)
1 results
All studies measuring HbA1c
Outcome: HbA1c
1 results
All studies measuring HOMA-B
Outcome: HOMA-B
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Date Seed Powder (DSP) improve homa-b?
Emerging Evidence
Date Seed Powder (DSP) appears to improve HOMA-B.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
HOMA-B
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Date Seed Powder (DSP) improve HbA1c?
Emerging Evidence
Date Seed Powder (DSP) appears to improve HbA1c.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Date Seed Powder (DSP) improve insulin?
Emerging Evidence
Date Seed Powder (DSP) appears to improve Insulin.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Insulin
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Date Seed Powder (DSP) improve insulin resistance?
Emerging Evidence
Date Seed Powder (DSP) appears to improve Insulin resistance.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Insulin resistance
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
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