Last updated August 24, 2026
Key finding
The intervention group showed significantly lower mean HbA1c levels (mean 6.76%, SD 0.64%) compared to the control group (mean 7.09%, SD 0.82%, P =.007).
This study evaluated an eHealth chronic disease management module's effect on glycemic control in diabetes patients, finding significant improvements in HbA1c levels.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated an eHealth chronic disease management module's effect on glycemic control in diabetes patients, finding significant improvements in HbA1c levels.
Improving glycemic control is crucial for diabetes management, as it can reduce the risk of complications. This study suggests that eHealth interventions can be effective tools for enhancing patient outcomes, making them valuable in clinical practice for managing diabetes.
The study's sample size may limit generalizability. No significant changes were observed in blood pressure or kidney function. Long-term effects of the intervention were not assessed.
Published in
Publication details and source links for this paper.
Amaryllis M, Abdul NA, Daniel T, et al. The Impact of an eHealth Chronic Disease Management Module on Glycemic Control in Patients with Diabetes: A Randomized Controlled Trial. JMIR Formative Research. 2025;9:e67761. doi:10.2196/67761
The intervention group showed a decrease in mean HbA1c levels by 0.33% (P = 0.007).
73.4% of the intervention group achieved optimal HbA1c levels compared to 49.3% in the control group (P = 0.004).
App usage scores decreased by 0.49 points from month 4 to month 8 (P < 0.001).
Evidence network
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This study contributes evidence to eHealth chronic disease management module and Achievement of HbA1c ≤ 6.5%, App usage score, Diastolic blood pressure, and 4 more.
This study contributes evidence to
Primary intervention
eHealth chronic disease management module
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
7
Evidence pairs
743
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
eHealth chronic disease management module → Achievement of HbA1c ≤ 6.5%
eHealth chronic disease management module → Achievement of HbA1c ≤ 6.5%
eHealth chronic disease management module → App usage score
eHealth chronic disease management module → App usage score
eHealth chronic disease management module → Diastolic blood pressure
eHealth chronic disease management module → Diastolic blood pressure
eHealth chronic disease management module → Estimated glomerular filtration rate
eHealth chronic disease management module → Estimated glomerular filtration rate
eHealth chronic disease management module → HbA1c
eHealth chronic disease management module → HbA1c
eHealth chronic disease management module → Systolic blood pressure
eHealth chronic disease management module → Systolic blood pressure
eHealth chronic disease management module → Urinary albumin-to-creatinine ratio
eHealth chronic disease management module → Urinary albumin-to-creatinine ratio
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on eHealth chronic disease management module and Achievement of HbA1c ≤ 6.5%, eHealth chronic disease management module and App usage score.
This study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Behavioral & Lifestyle
Behavioral & Lifestyle
Curated evidence collections and hubs this study is part of.
All studies measuring Achievement of HbA1c ≤ 6.5%
Measures Achievement of HbA1c ≤ 6.5% as a key outcome.
All studies measuring App usage score
Measures App usage score as a key outcome.
All studies measuring Blood Pressure
Measures Blood Pressure as a key outcome.
All studies on eHealth chronic disease management module
Contributes to eHealth chronic disease management module evidence base.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
eHealth chronic disease management module appears to improve achievement of HbA1c ≤ 6.5%.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Achievement of HbA1c ≤ 6.5%
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
eHealth chronic disease management module appears to lower HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of eHealth chronic disease management module for app usage score.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
App usage score
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of eHealth chronic disease management module for diastolic blood pressure.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Diastolic blood pressure
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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