Research Summary
Analyzed using Evidence Intelligence™

Exercise Intensity Does Not Affect NEPA in Type 2 Diabetes

Last updated September 3, 2026

Key finding

No time*group interactions were found for estimated NEAT in the MICT (β = -5.33, p = 0.366).

This study examined the effects of different exercise intensities on non-exercise physical activity and thermogenesis in individuals with Type 2 diabetes over one year. Results indicated no significant changes in estimated NEAT or NEPA across exercise groups.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Long-Term (1–5 y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study examined the effects of different exercise intensities on non-exercise physical activity and thermogenesis in individuals with Type 2 diabetes over one year. Results indicated no significant changes in estimated NEAT or NEPA across exercise groups.

Clinical relevance

Understanding the impact of exercise intensity on daily activity levels and calorie expenditure is crucial for managing Type 2 diabetes. This study suggests that simply increasing exercise intensity may not lead to improvements in non-exercise physical activity or thermogenesis, which are important for overall health and diabetes management.

Keep in mind

The study did not find significant effects, limiting conclusions about exercise intensity benefits. Results may not be generalizable to all individuals with Type 2 diabetes. The sample size and characteristics may restrict the applicability of findings.

Published in

Journal Reference

Publication details and source links for this paper.

Inês RC, Megan H, João PM, et al. Effects of Different Exercise Intensities on Non-Exercise Physical Activity and Estimated Thermogenesis in Individuals with Type 2 Diabetes: A 1-Year RCT. Acta Diabetologica. 2023;60(5):645-654. doi:10.1007/s00592-023-02038-7

Main Effects

No significant change in estimated NEAT for MICT (β = -5.33, p = 0.366).

No significant change in NEPA for MICT (β = -452.83, p = 0.833).

No significant change in estimated NEAT for HIIT (β = -5.70, p = 0.283).

No significant change in NEPA for HIIT (β = -2770.76, p = 0.201).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to High-intensity interval exercise, Moderate continuous exercise and Estimated Non-Exercise Activity Thermogenesis (NEAT), Physical activity level (MET-minutes per week).

Primary intervention

High-intensity interval exercise

Primary outcomes

  • Estimated Non-Exercise Activity Thermogenesis (NEAT)
  • Physical activity level (MET-minutes per week)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

4
Evidence pairs
4
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

3

Related topics

4

Evidence pairs

173

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 4 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Aerobic Exercise and Physical Activity Levels

Related evidence

Evidence topic

Physical Activity Levels

Save evidence

Evidence topic

Treatment Adherence

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Estimated Non-Exercise Activity Thermogenesis (NEAT)

High-intensity interval exercise → Estimated Non-Exercise Activity Thermogenesis (NEAT)

High-intensity interval exercise → Estimated Non-Exercise Activity Thermogenesis (NEAT)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Physical activity level (MET-minutes per week)

High-intensity interval exercise → Physical activity level (MET-minutes per week)

High-intensity interval exercise → Physical activity level (MET-minutes per week)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Estimated Non-Exercise Activity Thermogenesis (NEAT)

Moderate continuous exercise → Estimated Non-Exercise Activity Thermogenesis (NEAT)

Moderate continuous exercise → Estimated Non-Exercise Activity Thermogenesis (NEAT)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Physical activity level (MET-minutes per week)

Moderate continuous exercise → Physical activity level (MET-minutes per week)

Moderate continuous exercise → Physical activity level (MET-minutes per week)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • MICT showed no significant change in NEAT (-5.33 kcal/day, p = 0.366).
  • HIIT also showed no significant change in NEAT (-5.70 kcal/day, p = 0.283).
  • Both exercise types did not significantly affect NEPA.
who this applies

Who this applies to

  • Adults diagnosed with Type 2 diabetes.
  • Individuals looking to manage their diabetes through exercise.
keep in mind

Keep in Mind

  • The lack of significant findings suggests exercise intensity may not influence daily activity levels.
  • Further research is needed to explore other factors affecting NEAT and NEPA.
  • Results are specific to the sample studied and may not apply to all populations.
between the lines

Between the Lines

  • The study did not find significant effects, limiting conclusions about exercise intensity benefits.
  • Results may not be generalizable to all individuals with Type 2 diabetes.
  • The sample size and characteristics may restrict the applicability of findings.

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on High-intensity interval exercise and Estimated Non-Exercise Activity Thermogenesis (NEAT), High-intensity interval exercise and Physical Activity Levels.

Related evidence relationships

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This study contributes to the evidence on the following intervention-outcome relationships.

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Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Aerobic Exercise improve physical activity levels?

Emerging Evidence

Current evidence does not show a clear benefit of Aerobic Exercise for physical activity levels.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Physical activity level (MET-minutes per week)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does High-intensity interval exercise improve estimated non-exercise activity thermogenesis (NEAT)?

Emerging Evidence

Current evidence does not show a clear benefit of High-intensity interval exercise for estimated non-exercise activity thermogenesis (NEAT).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Estimated Non-Exercise Activity Thermogenesis (NEAT)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does High-intensity interval exercise improve physical activity level (met-minutes per week)?

Emerging Evidence

Current evidence does not show a clear benefit of High-intensity interval exercise for physical activity level (met-minutes per week).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Physical activity level (MET-minutes per week)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Moderate continuous exercise improve estimated non-exercise activity thermogenesis (NEAT)?

Emerging Evidence

Current evidence does not show a clear benefit of Moderate continuous exercise for estimated non-exercise activity thermogenesis (NEAT).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Estimated Non-Exercise Activity Thermogenesis (NEAT)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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