Last updated July 18, 2026
Key finding
After 16 wk, there was no significant between-group difference in HbA1c [Δ = −0.01%, 95% CI: −0.03, 0.06; P = 0.49].
This study evaluated the effectiveness of β-glucan-enriched bread on glycemic control in adults at risk of type 2 diabetes, finding no significant differences in key outcomes.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the effectiveness of β-glucan-enriched bread on glycemic control in adults at risk of type 2 diabetes, finding no significant differences in key outcomes.
Understanding the effectiveness of dietary interventions like β-glucan-enriched bread is crucial for developing strategies to prevent type 2 diabetes. This study highlights the need for further research into dietary options that can effectively support glycemic control in at-risk populations.
Limited sample size may affect generalizability. Short duration of the study may not capture long-term effects. No significant differences observed could indicate ineffectiveness.
Published in
Publication details and source links for this paper.
Therese H, Alena S, Ingrid R, et al. Effectiveness of β-glucan–enriched bread on glycemic control in adults at risk of type 2 diabetes. The American Journal of Clinical Nutrition. 2025;122(3):724-732. doi:10.1016/j.ajcnut.2025.06.018
No significant change in HbA1c (Δ = −0.01%, P = 0.49)
No significant change in FPG (Δ = −0.02 mmol/L)
No significant change in insulin levels (Δ = −0.76 pmol/L)
No significant change in LDL cholesterol (Δ = −0.11 mmol/L)
Evidence network
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This study contributes evidence to β-glucan-enriched bread and Fasting Plasma Glucose (FPG), HbA1c, Insulin, and 1 more.
This study contributes evidence to
Primary intervention
β-glucan-enriched bread
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
4
Evidence pairs
555
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
β-glucan-enriched bread → Fasting Plasma Glucose (FPG)
β-glucan-enriched bread → Fasting Plasma Glucose (FPG)
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on β-glucan-enriched bread and Fasting Glucose, β-glucan-enriched bread and HbA1c.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Adipokine and Angiogenic Markers
Measures Adipokine and Angiogenic Markers as a key outcome.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies on β-glucan-enriched bread
Contributes to β-glucan-enriched bread evidence base.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Current evidence does not show a clear benefit of β-glucan-enriched bread for Fasting Plasma Glucose (FPG).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of β-glucan-enriched bread for HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of β-glucan-enriched bread for Insulin.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Insulin
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of β-glucan-enriched bread for LDL cholesterol.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
LDL cholesterol
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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