Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerResearch Summary
Analyzed using Evidence Intelligence™
High protein diet improves fat loss and lowers blood pressure in obese women
Last updated September 2, 2026
Key finding
Diastolic blood pressure decreased more on HP (-3.7 mm Hg [95% CI: -6.2, -1.1; p = 0.005])
A high protein weight-reducing diet led to greater fat loss and lower blood pressure compared to a high carbohydrate, high fiber diet in overweight and obese women.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
A high protein weight-reducing diet led to greater fat loss and lower blood pressure compared to a high carbohydrate, high fiber diet in overweight and obese women.
Clinical relevance
These findings are significant for clinicians and patients as they highlight the potential benefits of a high protein diet for weight loss and cardiovascular health in overweight and obese women. With obesity being a major risk factor for various health issues, effective dietary strategies are essential for improving health outcomes in this population.
Keep in mind
Study focused only on women, limiting generalizability to men. Sample size and demographic characteristics may affect broader applicability. Effectiveness of diets may vary based on individual adherence and lifestyle factors.
Published in
Journal Reference
Publication details and source links for this paper.
Lisa ATM, Megan TL, Sheila MW, Rachel CB, Jim M. A realistic high protein weight-reducing diet was associated with greater fat loss and lower blood pressure when compared with a high carbohydrate, high fiber diet in high risk overweight and obese women. Nutrition Journal. 2011;10:40-40. doi:10.1186/1475-2891-10-40
Main Effects
Moderate-protein diet resulted in a weight loss of -4.5 kg [95% CI: -3.7, -5.4 kg].
Total body fat loss was -4.0 kg [95% CI: -4.6, -3.4 kg] with the moderate-protein diet.
Diastolic blood pressure decreased by -3.7 mm Hg [95% CI: -6.2, -1.1; p = 0.005] with the moderate-protein diet.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to High-fiber diet, Low-protein diet and Body fat mass, Diastolic blood pressure, Waist circumference, and 1 more.
This study contributes evidence to
Primary intervention
High-fiber diet
Primary outcomes
- Body fat mass
- Diastolic blood pressure
- Waist circumference
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
8
Evidence pairs
8
Relationships
3
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
3
Related topics
8
Evidence pairs
660
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 8 evidence relationships
- Includes primary outcome data
- Linked to 3 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
Body Composition
matched_outcome
Related evidence
Evidence topic
Weight Loss
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Diastolic blood pressure
High-fiber diet → Diastolic blood pressure
High-fiber diet → Diastolic blood pressure
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerWeight loss dependent effect on HbA1c
High-fiber diet → Weight loss dependent effect on HbA1c
High-fiber diet → Weight loss dependent effect on HbA1c
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Supporting studies: Based on 2 studies
Add to Evidence TrackerDiastolic blood pressure
Low-protein diet → Diastolic blood pressure
Low-protein diet → Diastolic blood pressure
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerWeight loss dependent effect on HbA1c
Low-protein diet → Weight loss dependent effect on HbA1c
Low-protein diet → Weight loss dependent effect on HbA1c
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Evidence Suggest
- High protein diet led to a weight loss of -4.5 kg compared to -3.3 kg for the high fiber diet.
- Total body fat loss was significantly greater with the moderate-protein diet (-4.0 kg vs -2.5 kg).
- Diastolic blood pressure reduction was more significant in the high protein group (-3.7 mm Hg).
Who this applies to
- Overweight and obese women at high risk for health complications.
- Individuals seeking effective dietary strategies for weight loss.
Keep in Mind
- Results may not apply to men or younger populations.
- Dietary adherence and lifestyle factors can influence outcomes.
- Further research is needed to explore long-term effects and sustainability of diets.
Between the Lines
- Study focused only on women, limiting generalizability to men.
- Sample size and demographic characteristics may affect broader applicability.
- Effectiveness of diets may vary based on individual adherence and lifestyle factors.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Low-protein diet and Body Composition, High-fiber diet and Body Composition.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Low-protein diet → Body Composition
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Supporting studies: Based on 2 studies
View evidenceDiet and Nutrition
High-fiber diet → Body Composition
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceDiet and Nutrition
High-fiber diet → Blood Pressure
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Body Composition Evidence Hub
All studies measuring Body Composition
2 studies
outcome_hubMeasures Body Composition as a key outcome.
Low-protein diet Evidence Hub
All studies on Low-protein diet
2 studies
intervention_hubContributes to Low-protein diet evidence base.
Blood Pressure Evidence Hub
All studies measuring Blood Pressure
1 studies
outcome_hubMeasures Blood Pressure as a key outcome.
High-fiber diet Evidence Hub
All studies on High-fiber diet
1 studies
intervention_hubContributes to High-fiber diet evidence base.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Low-protein diet and Body fat mass
Intervention: Low-protein dietOutcome: Body fat mass
2 results
All studies on High-fiber diet and Body fat mass
Intervention: High-fiber dietOutcome: Body fat mass
1 results
All studies on Low-protein diet
Intervention: Low-protein diet
2 results
All studies on High-fiber diet
Intervention: High-fiber diet
1 results
All studies measuring Body fat mass
Outcome: Body fat mass
2 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Low-protein diet improve body fat mass?
Moderate Evidence
Low-protein diet may improve body fat mass.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
Body fat mass
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only one supporting study is available.
Does High-fiber diet improve body fat mass?
Emerging Evidence
High-fiber diet appears to improve body fat mass.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Body fat mass
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does High-fiber diet affect waist circumference?
Emerging Evidence
High-fiber diet appears to affect waist circumference.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Waist circumference
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does High-fiber diet affect weight loss dependent effect on HbA1c?
Emerging Evidence
High-fiber diet appears to affect weight loss dependent effect on HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Weight loss dependent effect on HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Next steps
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