Last updated September 9, 2026
Key finding
Offspring of mothers in the intervention group were born 0.64 cm shorter compared to those in the usual-care group.
The MySweetheart trial evaluated a pre- and postpartum lifestyle intervention for women with gestational diabetes, finding no significant differences in most outcomes except for a slight reduction in birth length.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
The MySweetheart trial evaluated a pre- and postpartum lifestyle intervention for women with gestational diabetes, finding no significant differences in most outcomes except for a slight reduction in birth length.
Understanding the impact of lifestyle interventions on gestational diabetes is crucial for improving maternal and infant health. Although this study showed a minor reduction in birth length, the lack of significant differences in other outcomes suggests that more research is needed to determine effective strategies for managing gestational diabetes.
The study may have limited generalizability due to its specific population. The sample size and demographic characteristics were not detailed. The intervention's long-term effects were not assessed.
Published in
Publication details and source links for this paper.
Leah G, Dan YQ, Amar A, et al. The MySweetheart trial: A pre- and postpartum multidimensional interdisciplinary lifestyle and psychosocial intervention in women with gestational diabetes. Frontiers in Endocrinology. 2023;14:1148426. doi:10.3389/fendo.2023.1148426
Offspring of mothers in the intervention group were born 0.64 cm shorter compared to those in the usual-care group.
There were no differences between groups in offspring weight at birth.
No differences were found in the incidence of macrosomia or small/large for gestational age.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Lifestyle intervention for prediabetes and Birth length, Healing proportion of diabetic foot ulcers, Incidence of macrosomia, and 5 more.
This study contributes evidence to
Primary intervention
Lifestyle intervention for prediabetes
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
1
Related topics
8
Evidence pairs
106
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Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_intervention_and_outcome
Core evidence
The primary outcomes reported in this study.
Lifestyle intervention for prediabetes → Birth length
Lifestyle intervention for prediabetes → Birth length
Lifestyle intervention for prediabetes → Healing proportion of diabetic foot ulcers
Lifestyle intervention for prediabetes → Healing proportion of diabetic foot ulcers
Lifestyle intervention for prediabetes → Incidence of macrosomia
Lifestyle intervention for prediabetes → Incidence of macrosomia
Lifestyle intervention for prediabetes → Neonatal birth weight
Lifestyle intervention for prediabetes → Neonatal birth weight
Lifestyle intervention for prediabetes → Night wakings score
Lifestyle intervention for prediabetes → Night wakings score
Lifestyle intervention for prediabetes → Proportion of large-for-gestational-age newborns
Lifestyle intervention for prediabetes → Proportion of large-for-gestational-age newborns
Lifestyle intervention for prediabetes → Sleep Duration at Night
Lifestyle intervention for prediabetes → Sleep Duration at Night
Lifestyle intervention for prediabetes → Small for gestational age infants
Lifestyle intervention for prediabetes → Small for gestational age infants
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Lifestyle intervention for prediabetes and Incidence of macrosomia, Lifestyle intervention for prediabetes and Birth length.
This study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Behavioral & Lifestyle
Behavioral & Lifestyle
Curated evidence collections and hubs this study is part of.
All studies measuring Incidence of macrosomia
Measures Incidence of macrosomia as a key outcome.
All studies on Lifestyle intervention for prediabetes
Contributes to Lifestyle intervention for prediabetes evidence base.
All studies measuring Birth length
Measures Birth length as a key outcome.
All studies measuring Neonatal birth weight
Measures Neonatal birth weight as a key outcome.
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2 results
1 results
2 results
2 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Current evidence does not show a clear reduction in incidence of macrosomia with Lifestyle intervention for prediabetes.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Incidence of macrosomia
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | neutral | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Lifestyle intervention for prediabetes for birth length.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Birth length
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Lifestyle intervention for prediabetes for healing proportion of diabetic foot ulcers.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Healing proportion of diabetic foot ulcers
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Lifestyle intervention for prediabetes for neonatal birth weight.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Neonatal birth weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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