PrediabetesPreventionBehavioral InterventionNutrition & Diet
Research Summary
Analyzed using Evidence Intelligence™

Lifestyle programme linked to lasting weight loss in some adults at high diabetes risk

Last updated June 15, 2026

Key finding

Mean weight loss 4.2 kg during intervention among responders; total weight loss in maintainers at 3 years was 6.54 kg, while non-maintainers returned to baseline (+0.21 kg)

This study followed adults at high risk of type 2 diabetes after a primary-care lifestyle programme in Poland. Among the 105 people with complete 3-year follow-up, many lost weight during the intervention and a smaller subgroup kept that weight off afterward. Because there was no concurrent control group in this analysis, the findings should be interpreted cautiously.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

Non-randomized interventional follow-up analysis

Follow-up

Long-Term (1–5 y)

Risk of bias

High Risk

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study followed adults at high risk of type 2 diabetes after a primary-care lifestyle programme in Poland. Among the 105 people with complete 3-year follow-up, many lost weight during the intervention and a smaller subgroup kept that weight off afterward. Because there was no concurrent control group in this analysis, the findings should be interpreted cautiously.

Clinical relevance

Diabetes prevention programmes often achieve short-term weight loss, but maintenance is much harder. This study suggests that continued dietary behavior change, especially reducing total fat intake, may help preserve weight loss after a primary-care lifestyle programme. These findings can inform programme design, although the lack of a control group means they should not be over-interpreted.

Keep in mind

No parallel control group in the analyzed long-term cohort Only 105 participants had complete measurements across all three examinations Predictor analyses compare maintainers with non-maintainers within the intervention cohort Diet and physical activity changes were self-reported

Main Effects

↓ Mean weight loss during intervention among responders was 4.2 kg at 1 year

↓ Maintainers achieved total 3-year weight loss of 6.54 kg, while non-maintainers returned near baseline (+0.21 kg)

↓ Waist circumference fell more in maintainers (−5.26 cm) than in non-maintainers (−0.33 cm)

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Lifestyle intervention for prediabetes and Body fat mass, Body weight, Fasting blood sugar (FBS), and 2 more.

Primary intervention

Lifestyle intervention for prediabetes

Primary outcomes

  • Body fat mass
  • Body weight
  • Fasting blood sugar (FBS)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

5
Evidence pairs
5
Relationships
5
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

5

Related topics

5

Evidence pairs

671

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 5 evidence relationships
  • Includes primary outcome data
  • Linked to 5 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

Prediabetes

matched_intervention_and_outcome

Related evidence

Evidence topic

Weight Loss

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Body fat mass

Lifestyle intervention for prediabetes → Body fat mass

Lifestyle intervention for prediabetes → Body fat mass

Evidence Intelligence™
EvidenceScore™
56
Emerging
ImpactScore™
55
Slightly Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Body weight

Lifestyle intervention for prediabetes → Body weight

Lifestyle intervention for prediabetes → Body weight

Evidence Intelligence™
EvidenceScore™
85
Strong
ImpactScore™
63
Slightly Positive
ConsistencyScore™
75
consistent
Supporting studies: Based on 8 studies
Add to Evidence Tracker

Fasting blood sugar (FBS)

Lifestyle intervention for prediabetes → Fasting blood sugar (FBS)

Lifestyle intervention for prediabetes → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
76
Strong
ImpactScore™
64
Slightly Positive
ConsistencyScore™
67
generally_consistent
Supporting studies: Based on 4 studies
Add to Evidence Tracker

Physical activity level (MET-minutes per week)

Lifestyle intervention for prediabetes → Physical activity level (MET-minutes per week)

Lifestyle intervention for prediabetes → Physical activity level (MET-minutes per week)

Evidence Intelligence™
EvidenceScore™
63
Moderate
ImpactScore™
77
Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Waist circumference

Lifestyle intervention for prediabetes → Waist circumference

Lifestyle intervention for prediabetes → Waist circumference

Evidence Intelligence™
EvidenceScore™
76
Strong
ImpactScore™
64
Slightly Positive
ConsistencyScore™
75
consistent
Supporting studies: Based on 4 studies
Add to Evidence Tracker

Evidence Library

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keep in mind

Keep in Mind

  • No parallel control group in the analyzed long-term cohort Only 105 participants had complete measurements across all three examinations Predictor analyses compare maintainers with non-maintainers within the intervention cohort Diet and physical activity changes were self-reported
between the lines

Between the Lines

  • No parallel control group in the analyzed long-term cohort Only 105 participants had complete measurements across all three examinations Predictor analyses compare maintainers with non-maintainers within the intervention cohort Diet and physical activity changes were self-reported

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Lifestyle intervention for prediabetes and Body Weight, Lifestyle intervention for prediabetes and Fasting Glucose.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Lifestyle intervention for prediabetes affect body weight?

Strong Evidence

Lifestyle intervention for prediabetes may improve Body weight.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Body weight

    EvidenceScore™ Strong | EvidenceScore™ 85.3 | weak positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Lifestyle intervention for prediabetes affect waist circumference?

Strong Evidence

Lifestyle intervention for prediabetes may improve Waist circumference.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Waist circumference

    EvidenceScore™ Strong | EvidenceScore™ 75.6 | weak positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Lifestyle intervention for prediabetes improve fasting blood sugar (fbs)?

Strong Evidence

Lifestyle intervention for prediabetes may improve Fasting blood sugar (FBS).

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    Fasting blood sugar (FBS)

    EvidenceScore™ Strong | EvidenceScore™ 75.6 | weak positive | ConsistencyScore™ Generally Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Lifestyle intervention for prediabetes improve physical activity level (met-minutes per week)?

Moderate Evidence

Lifestyle intervention for prediabetes may improve Physical activity level (MET-minutes per week).

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Physical activity level (MET-minutes per week)

    EvidenceScore™ Moderate | EvidenceScore™ 63.0 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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