Last updated September 9, 2026
Key finding
Women in the intervention group developed significantly less often metabolic syndrome compared to the control group [7.3% (6) vs. 16.5% (14), OR 0.40, CI (0.22–0.72), p = 0.002]
This study evaluated the efficacy of a blended mobile-based lifestyle intervention for women with glucose intolerance following gestational diabetes mellitus. The intervention showed promising results in achieving weight goals and reducing metabolic syndrome incidence.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Extended (5–20+ y)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the efficacy of a blended mobile-based lifestyle intervention for women with glucose intolerance following gestational diabetes mellitus. The intervention showed promising results in achieving weight goals and reducing metabolic syndrome incidence.
This study highlights the potential of mobile-based interventions in managing health outcomes for women with a history of gestational diabetes. By improving weight management and reducing metabolic syndrome risk, such interventions could play a crucial role in preventing future diabetes and related health issues.
Effectiveness of the intervention remains unclear for some outcomes. Sample size may limit generalizability of findings. Potential confounding factors were not fully controlled.
Published in
Publication details and source links for this paper.
Caro M, Nele M, Toon M, et al. Efficacy of a blended mobile-based lifestyle intervention in women with glucose intolerance after gestational diabetes mellitus: A randomized controlled trial. eClinicalMedicine. 2024;70:102523. doi:10.1016/j.eclinm.2024.102523
46.3% of intervention participants achieved weight goals compared to 43.3% in the control group.
7.3% of women in the intervention group developed metabolic syndrome versus 16.5% in the control group.
Diabetes incidence was lower in the intervention group at 3.7% compared to 5.9% in the control group.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Lifestyle intervention for prediabetes and Frequency of glucose intolerance, Incidence of Metabolic Syndrome at 3 Years Postpartum, Motivation for healthy behaviors, and 3 more.
This study contributes evidence to
Primary intervention
Lifestyle intervention for prediabetes
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
6
Evidence pairs
385
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_intervention_and_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
Lifestyle intervention for prediabetes → Frequency of glucose intolerance
Lifestyle intervention for prediabetes → Frequency of glucose intolerance
Lifestyle intervention for prediabetes → Incidence of Metabolic Syndrome at 3 Years Postpartum
Lifestyle intervention for prediabetes → Incidence of Metabolic Syndrome at 3 Years Postpartum
Lifestyle intervention for prediabetes → Motivation for healthy behaviors
Lifestyle intervention for prediabetes → Motivation for healthy behaviors
Lifestyle intervention for prediabetes → Proportion of participants meeting weight goal
Lifestyle intervention for prediabetes → Proportion of participants meeting weight goal
Lifestyle intervention for prediabetes → Sedentary behavior
Lifestyle intervention for prediabetes → Sedentary behavior
Lifestyle intervention for prediabetes → Type 2 diabetes incidence
Lifestyle intervention for prediabetes → Type 2 diabetes incidence
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Lifestyle intervention for prediabetes and Diabetes Incidence and Prevention, Lifestyle intervention for prediabetes and Incidence of Metabolic Syndrome at 3 Years Postpartum.
This study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Behavioral & Lifestyle
Behavioral & Lifestyle
Curated evidence collections and hubs this study is part of.
All studies measuring Diabetes Incidence and Prevention
Measures Diabetes Incidence and Prevention as a key outcome.
All studies on Lifestyle intervention for prediabetes
Contributes to Lifestyle intervention for prediabetes evidence base.
All studies measuring Incidence of Metabolic Syndrome at 3 Years Postpartum
Measures Incidence of Metabolic Syndrome at 3 Years Postpartum as a key outcome.
All studies measuring Proportion of participants meeting weight goal
Measures Proportion of participants meeting weight goal as a key outcome.
Latest published studies
Published within the last 2 years.
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7 results
2 results
7 results
7 results
2 results
Generated from the study's connected evidence using Evidence Intelligence™.
Lifestyle intervention for prediabetes may reduce type 2 diabetes incidence.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
Type 2 diabetes incidence
EvidenceScore™ Strong | EvidenceScore™ 85.7 | weak positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
Lifestyle intervention for prediabetes may reduce incidence of metabolic syndrome at 3 years postpartum.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
Incidence of Metabolic Syndrome at 3 Years Postpartum
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
Lifestyle intervention for prediabetes appears to improve motivation for healthy behaviors.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Motivation for healthy behaviors
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Lifestyle intervention for prediabetes for frequency of glucose intolerance.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Frequency of glucose intolerance
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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