Research Summary
Analyzed using Evidence Intelligence™

Office-GAP + Texting Improves Medication Adherence in T2 Diabetes

Last updated July 11, 2026

Key finding

Primary outcome is medication adherence measured using eCAP electronic monitoring and self-report.

This study evaluated the effectiveness of two behavioral interventions aimed at improving medication adherence in adults with Type 2 diabetes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Long-Term (1–5 y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the effectiveness of two behavioral interventions aimed at improving medication adherence in adults with Type 2 diabetes.

Clinical relevance

Improving medication adherence is crucial for managing Type 2 diabetes effectively, as it can lead to better health outcomes and reduced risk of complications. Understanding the effectiveness of different interventions can help healthcare providers choose the best strategies for their patients.

Keep in mind

Unclear effectiveness findings limit the ability to draw strong conclusions. Study design may affect generalizability to broader populations. Limited sample size may impact the reliability of the results.

Published in

Journal Reference

Publication details and source links for this paper.

Adesuwa O, Karen K, William H, et al. Improving Medication Adherence in Adults with Type 2 Diabetes: A Pragmatic Cluster-Randomized Trial. Trials. 2022;23:659. doi:10.1186/s13063-022-06581-6

Main Effects

Unclear effectiveness on medication adherence using eCAP electronic monitoring and self-report.

Unclear effectiveness on diabetes-specific 5-year CVD risk measured with the UKPDS Engine score.

Unclear effectiveness on provider engagement as measured by the CollaboRATE Shared-Decision Making measure.

Unclear effectiveness on patient activation measures (PAM).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Office-Gap + Texting and Diabetes-specific 5-year CVD risk as measured with the UKPDS Engine score, Patient Activation, Patient engagement, and 1 more.

Primary intervention

Office-Gap + Texting

Primary outcomes

  • Diabetes-specific 5-year CVD risk as measured with the UKPDS Engine score
  • Patient Activation
  • Patient engagement

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

4
Evidence pairs
4
Relationships
1
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 59

1

Related topics

4

Evidence pairs

70

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 4 evidence relationships
  • Includes primary outcome data
  • Linked to 1 direct semantic evidence topic

Topic contributions

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence topic

Treatment Adherence

matched_outcome

Core evidence

Study findings

The primary outcomes reported in this study.

Diabetes-specific 5-year CVD risk as measured with the UKPDS Engine score

Office-Gap + Texting → Diabetes-specific 5-year CVD risk as measured with the UKPDS Engine score

Office-Gap + Texting → Diabetes-specific 5-year CVD risk as measured with the UKPDS Engine score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Patient Activation

Office-Gap + Texting → Patient Activation

Office-Gap + Texting → Patient Activation

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Patient engagement

Office-Gap + Texting → Patient engagement

Office-Gap + Texting → Patient engagement

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Proportion of participants with good medication adherence

Office-Gap + Texting → Proportion of participants with good medication adherence

Office-Gap + Texting → Proportion of participants with good medication adherence

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Both interventions showed unclear effectiveness in improving medication adherence.
  • Secondary outcomes also indicated unclear effectiveness.
  • Further research is needed to clarify intervention impacts.
who this applies

Who this applies to

  • Adults diagnosed with Type 2 diabetes.
  • Participants engaged in behavioral interventions for medication adherence.
keep in mind

Keep in Mind

  • Results may not be applicable to all populations with Type 2 diabetes.
  • The study's design limits definitive conclusions about intervention effectiveness.
  • Further studies are necessary to explore alternative strategies for improving adherence.
between the lines

Between the Lines

  • Unclear effectiveness findings limit the ability to draw strong conclusions.
  • Study design may affect generalizability to broader populations.
  • Limited sample size may impact the reliability of the results.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Office-Gap + Texting and Diabetes-specific 5-year CVD risk as measured with the UKPDS Engine score, Office-Gap + Texting and Patient Activation.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Office-Gap + Texting improve proportion of participants with good medication adherence?

Emerging Evidence

Office-Gap + Texting appears to improve Proportion of participants with good medication adherence.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Proportion of participants with good medication adherence

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Office-Gap + Texting improve diabetes-specific 5-year cvd risk as measured with the ukpds engine score?

Emerging Evidence

Current evidence does not show a clear benefit of Office-Gap + Texting for Diabetes-specific 5-year CVD risk as measured with the UKPDS Engine score.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Diabetes-specific 5-year CVD risk as measured with the UKPDS Engine score

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Office-Gap + Texting improve patient activation?

Emerging Evidence

Current evidence does not show a clear benefit of Office-Gap + Texting for Patient Activation.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Patient Activation

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Office-Gap + Texting improve patient engagement?

Emerging Evidence

Current evidence does not show a clear benefit of Office-Gap + Texting for Patient engagement.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Patient engagement

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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