Research Summary
Analyzed using Evidence Intelligence™

Periodontal treatment improves glycemic control in type 2 diabetes

Last updated July 22, 2026

Key finding

Mean difference -0.89, statistically significant change at P value = 0.000.

This study evaluated the impact of improved periodontal health on glycemic control in type 2 diabetes patients with generalized periodontitis, revealing significant changes in several periodontal measures.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the impact of improved periodontal health on glycemic control in type 2 diabetes patients with generalized periodontitis, revealing significant changes in several periodontal measures.

Clinical relevance

This research highlights the importance of periodontal health in managing type 2 diabetes, suggesting that dental treatments may have broader health implications. Improved gum health could potentially enhance overall health outcomes for diabetic patients, emphasizing the need for integrated care approaches.

Keep in mind

Limited sample size may affect generalizability. Short follow-up period may not capture long-term effects. Potential confounding factors not controlled for.

Published in

Journal Reference

Publication details and source links for this paper.

Sukhdeep S, Veerendra K, Sheela K, Anitha S. The effect of improved periodontal health on glycemic control in type 2 diabetes mellitus patients with generalized periodontitis. International Journal of Diabetes in Developing Countries. 2008;28(2):38-44. doi:10.4103/0973-3930.43097

Main Effects

Plaque index decreased by 0.89 (p=0.000)

Gingival index decreased by 0.74 (p=0.000)

Postprandial blood glucose decreased by 21.8 (statistically significant)

HbA1c decreased by 0.7 (statistically significant)

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Scaling and root planing followed by systemic doxycycline, Scaling and root planing only and Fasting Plasma Glucose (FPG), Glucose iAUC (OGTT), HbA1c, and 4 more.

Primary intervention

Scaling and root planing followed by systemic doxycycline

Primary outcomes

  • Fasting Plasma Glucose (FPG)
  • Glucose iAUC (OGTT)
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

2

Related topics

7

Evidence pairs

555

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence topic

Glycemic Control

matched_outcome

Related evidence

Evidence topic

HbA1c Reduction

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Fasting Plasma Glucose (FPG)

Scaling and root planing followed by systemic doxycycline → Fasting Plasma Glucose (FPG)

Scaling and root planing followed by systemic doxycycline → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Glucose iAUC (OGTT)

Scaling and root planing followed by systemic doxycycline → Glucose iAUC (OGTT)

Scaling and root planing followed by systemic doxycycline → Glucose iAUC (OGTT)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Scaling and root planing followed by systemic doxycycline → HbA1c

Scaling and root planing followed by systemic doxycycline → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Clinical attachment level

Scaling and root planing only → Clinical attachment level

Scaling and root planing only → Clinical attachment level

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Gingival Index (GI)

Scaling and root planing only → Gingival Index (GI)

Scaling and root planing only → Gingival Index (GI)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Periodontal probing depth

Scaling and root planing only → Periodontal probing depth

Scaling and root planing only → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Plaque Index (PI)

Scaling and root planing only → Plaque Index (PI)

Scaling and root planing only → Plaque Index (PI)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Significant reduction in plaque index (mean difference -0.89).
  • Gingival index showed significant improvement (mean difference -0.74).
  • Postprandial blood glucose decreased significantly (mean difference -21.8).
who this applies

Who this applies to

  • Adults with type 2 diabetes.
  • Patients diagnosed with generalized periodontitis.
keep in mind

Keep in Mind

  • Results may not apply to populations outside the study group.
  • Further research is needed to confirm long-term effects.
  • Glycemic control improvements were not consistent across all measures.
between the lines

Between the Lines

  • Limited sample size may affect generalizability.
  • Short follow-up period may not capture long-term effects.
  • Potential confounding factors not controlled for.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Scaling and root planing followed by systemic doxycycline and Fasting Glucose, Scaling and root planing followed by systemic doxycycline and Postprandial and OGTT Glucose.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Scaling and root planing followed by systemic doxycycline improve HbA1c?

Emerging Evidence

Scaling and root planing followed by systemic doxycycline appears to improve HbA1c.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Scaling and root planing only improve clinical attachment level?

Emerging Evidence

Scaling and root planing only appears to improve Clinical attachment level.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Clinical attachment level

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Scaling and root planing only improve gingival index (gi)?

Emerging Evidence

Scaling and root planing only appears to improve Gingival Index (GI).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Gingival Index (GI)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Scaling and root planing only improve periodontal probing depth?

Emerging Evidence

Scaling and root planing only appears to improve Periodontal probing depth.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Periodontal probing depth

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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