Last updated August 16, 2026
Key finding
The reduction in probing pocket depth was statistically significant (p = 0.04).
This study evaluated the impact of ozonated gel application alongside scaling and root planing in diabetic patients with stage III periodontitis, finding significant improvements in clinical outcomes.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the impact of ozonated gel application alongside scaling and root planing in diabetic patients with stage III periodontitis, finding significant improvements in clinical outcomes.
These findings are important for clinicians treating diabetic patients with periodontitis, as they suggest that ozonated gel could enhance treatment outcomes. Improved clinical attachment and reduced probing depth may lead to better long-term oral health and management of periodontal disease in this vulnerable population.
Limited sample size may affect generalizability Short follow-up period of 6 months Potential biases in participant selection
Published in
Publication details and source links for this paper.
Abeer AB, Nesma S, Arwa M, Mona D. The effect of subgingival application of ozonated gel as an adjunct to scaling and root planing in diabetic patients with stage III periodontitis. BMC Oral Health. 2024;24:1435. doi:10.1186/s12903-024-05212-7
Clinical attachment level significantly reduced (p = 0.04)
Probing pocket depth decreased by -1.25 mm (p = 0.04)
Visual Analogue Scale (VAS) scores showed significant differences (p = 0.017)
Evidence network
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This study contributes evidence to Scaling and root planing only and Clinical attachment level, Dentinal hypersensitivity measured as sensitivity to cold stimuli, Full mouth bleeding score, and 7 more.
This study contributes evidence to
Primary intervention
Scaling and root planing only
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
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Related topics
10
Evidence pairs
348
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Contributes evidence
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Primary evidence
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Related evidence
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Core evidence
The primary outcomes reported in this study.
Scaling and root planing only → Clinical attachment level
Scaling and root planing only → Clinical attachment level
Scaling and root planing only → Dentinal hypersensitivity measured as sensitivity to cold stimuli
Scaling and root planing only → Dentinal hypersensitivity measured as sensitivity to cold stimuli
Scaling and root planing only → Full mouth bleeding score
Scaling and root planing only → Full mouth bleeding score
Scaling and root planing only → Full mouth plaque score percentage
Scaling and root planing only → Full mouth plaque score percentage
Scaling and root planing only → Neuropathic pain severity
Scaling and root planing only → Neuropathic pain severity
Scaling and root planing only → Periodontal ligament widening space
Scaling and root planing only → Periodontal ligament widening space
Scaling and root planing only → Periodontal probing depth
Scaling and root planing only → Periodontal probing depth
Scaling and root planing only → Radiographic defect angle
Scaling and root planing only → Radiographic defect angle
Scaling and root planing only → Radiographic depth of bone defect
Scaling and root planing only → Radiographic depth of bone defect
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Scaling and Root Planing Procedures and Clinical attachment level, Scaling and Root Planing Procedures and Periodontal probing depth.
This study contributes to the evidence on the following intervention-outcome relationships.
Curated evidence collections and hubs this study is part of.
All studies measuring Clinical attachment level
Measures Clinical attachment level as a key outcome.
All studies measuring Periodontal probing depth
Measures Periodontal probing depth as a key outcome.
All studies on Scaling and Root Planing Procedures
Contributes to Scaling and Root Planing Procedures evidence base.
Latest published studies
Published within the last 2 years.
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3 results
3 results
3 results
3 results
3 results
Generated from the study's connected evidence using Evidence Intelligence™.
Scaling and Root Planing Procedures appears to improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | neutral | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 5 supporting studies with consistent results and a positive effect signal.
Limitations
Scaling and Root Planing Procedures appears to improve Neuropathy.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Neuropathic pain severity
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Scaling and root planing only may improve Clinical attachment level.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Clinical attachment level
EvidenceScore™ Strong | EvidenceScore™ 79.0 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Scaling and root planing only appears to improve Periodontal probing depth.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Periodontal probing depth
EvidenceScore™ Strong | EvidenceScore™ 78.6 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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